Cover image for Vol. 66 Issue 3

Edited By: Bruce R. Ransom and Helmut Kettenmann

Impact Factor: 6.2

ISI Journal Citation Reports © Ranking: 2016: 25/259 (Neurosciences)

Online ISSN: 1098-1136

Recently Published Issues

See all

Quick Links

2016 Impact Factor:
GLIA is pleased to announce its new Impact Factor is 6.2!

2017 Release of Journal Citation Reports®. Source: Thomson Reuters 2016 Citation Data

Recently Published Articles

  1. Cocaine and HIV-1 Tat disrupt cholesterol homeostasis in astrocytes: Implications for HIV-associated neurocognitive disorders in cocaine user patients

    Bianca Cotto, Kalimuthusamy Natarajaseenivasan, Kimberly Ferrero, Leroy Wesley, Matthew Sayre and Dianne Langford

    Version of Record online: 13 JAN 2018 | DOI: 10.1002/glia.23291

    Thumbnail image of graphical abstract

    Main Points

    • Liver X receptors (LXRs) are the master regulators of cholesterol homeostasis in the central nervous system.
    • HIV-1 infection and cocaine abuse disrupt cholesterol homeostasis.
    • Cocaine and HIV-1 Tat disrupt astrocyte LXR signaling leading to decreased bioavailability of cholesterol.
  2. Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs)

    Rosa M. Gómez, Magdy Y. Sánchez, Maria Portela-Lomba, Kemel Ghotme, George E. Barreto, Javier Sierra and M. Teresa Moreno-Flores

    Version of Record online: 13 JAN 2018 | DOI: 10.1002/glia.23282

  3. White matter tauopathy: Transient functional loss and novel myelin remodeling

    Joshua Jackson, Gabby Bianco, Angelo O Rosa, Katrina Cowan, Peter Bond, Oleg Anichtchik and Robert Fern

    Version of Record online: 8 JAN 2018 | DOI: 10.1002/glia.23286

    Thumbnail image of graphical abstract

    Main Points

    • Mutant tau induction produced myelin pathology within weeks associated with failure of action potential conduction.
    • Myelin remodeling accompanied continued transgene induction, producing a thin myelin phenotype with restored excitability.
  4. Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion

    Sage Begolly, John A. Olschowka, Tanzy Love, Jacqueline P. Williams and M. Kerry O'Banion

    Version of Record online: 30 DEC 2017 | DOI: 10.1002/glia.23288

    Thumbnail image of graphical abstract

    Main Points

    Fractionated radiation depletes oligodendrocyte progenitor cells (OPC) through direct killing of dividing cells and stimulating OPC proliferation. Together with effects on the microenvironment, this leads to long-term defects in white matter.

  5. ProMoIJ: A new tool for automatic three-dimensional analysis of microglial process motility

    Iñaki Paris, Julie C. Savage, Laura Escobar, Oihane Abiega, Steven Gagnon, Chin-Wai Hui, Marie-Ève Tremblay, Amanda Sierra and Jorge Valero

    Version of Record online: 30 DEC 2017 | DOI: 10.1002/glia.23287

    Thumbnail image of graphical abstract

    Main Points

    ProMoIJ allows 3D analysis of cell process motility and presents several advantages compared with manual protocols:

    • Reduced analysis time.
    • Reduced sensitiveness to experimenter bias.
    • Increased robustness to the number of processes analyzed.