Cover image for Vol. 65 Issue 11

Edited By: Bruce R. Ransom and Helmut Kettenmann

Impact Factor: 6.2

ISI Journal Citation Reports © Ranking: 2016: 23/258 (Neurosciences)

Online ISSN: 1098-1136

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2016 Impact Factor:
GLIA is pleased to announce its new Impact Factor is 6.2!

2017 Release of Journal Citation Reports®. Source: Thomson Reuters 2016 Citation Data

Recently Published Articles

  1. Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis

    Janusz J. Jadasz, Lena Tepe, Felix Beyer, Iria Samper Agrelo, Rainer Akkermann, Lucas-Sebastian Spitzhorn, Maria Elena Silva, Richard O. C. Oreffo, Hans-Peter Hartung, Alessandro Prigione, Francisco J. Rivera, James Adjaye and Patrick Küry

    Version of Record online: 22 SEP 2017 | DOI: 10.1002/glia.23233

    Thumbnail image of graphical abstract

    Main Points

    • Human fetal MSCs potently instruct oligodendrogenesis from adult rat hippocampal- and hIPSC-derived neural stem cells.
    • Oligodendrocyte generation does not depend on nuclear p57kip2 protein shuttling as opposed to parenchymal OPC differentiation.
  2. Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

    Emily G. Baxi, Joseph DeBruin, Jing Jin, Hayley J. Strasburger, Matthew D. Smith, Jennifer L. Orthmann-Murphy, Jason T. Schott, Amanda N. Fairchild, Dwight E. Bergles and Peter A. Calabresi

    Version of Record online: 22 SEP 2017 | DOI: 10.1002/glia.23229

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    Main Points

    • The timing and efficiency of remyelination in gray matter is distinct from white matter.
    • Our studies indicate that the temporal dynamics of OPC differentiation varies significantly between white and gray matter.
  3. Mechanical plasticity during oligodendrocyte differentiation and myelination

    Helena S. Domingues, Andrea Cruz, Jonah R. Chan, João B. Relvas, Boris Rubinstein and Inês Mendes Pinto

    Version of Record online: 21 SEP 2017 | DOI: 10.1002/glia.23206

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    Main Points

    • Oligodendrocytes reprogram their fate via actin and actomyosin cytoskeleton dynamics;
    • -g-ratio is independent of axon radius and it can be self-regulated by the geometrical and mechanical properties of the myelin sheath
  4. You have full text access to this OnlineOpen article
    Nestin-expressing cell types in the temporal lobe and hippocampus: Morphology, differentiation, and proliferative capacity

    Joan Liu, Cheryl Reeves, Thomas Jacques, Andrew McEvoy, Anna Miserocchi, Pamela Thompson, Sanjay Sisodiya and Maria Thom

    Version of Record online: 19 SEP 2017 | DOI: 10.1002/glia.23211

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    • Adult hippocampal nestin-expressing cells include radial glial with proliferative capacity and glial and neuronal differentiation.
    • They are of relevance to hippocampal epileptogenesis, epilepsy-related pathologies and co-morbidities.
  5. Combined fetal inflammation and postnatal hypoxia causes myelin deficits and autism-like behavior in a rat model of diffuse white matter injury

    Erik van Tilborg, E. J. Marijke Achterberg, Caren M. van Kammen, Annette van der Toorn, Floris Groenendaal, Rick M. Dijkhuizen, Cobi J. Heijnen, Louk J. M. J. Vanderschuren, Manon N. J. L. Benders and Cora H. A. Nijboer

    Version of Record online: 19 SEP 2017 | DOI: 10.1002/glia.23216

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    Main Points

    • Combined inflammation in utero and postnatal hypoxia causes impaired oligodendrocyte maturation, myelin deficits and behavioral problems in rats.
    • This model may be used to study treatment options for diffuse white matter injury in preterm infants.