Cover image for Vol. 66 Issue 2

Edited By: Bruce R. Ransom and Helmut Kettenmann

Impact Factor: 6.2

ISI Journal Citation Reports © Ranking: 2016: 25/259 (Neurosciences)

Online ISSN: 1098-1136

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2016 Impact Factor:
GLIA is pleased to announce its new Impact Factor is 6.2!

2017 Release of Journal Citation Reports®. Source: Thomson Reuters 2016 Citation Data

Recently Published Articles

  1. Neonatal mouse cortical but not isogenic human astrocyte feeder layers enhance the functional maturation of induced pluripotent stem cell-derived neurons in culture

    Fritz W. Lischka, Anastasia Efthymiou, Qiong Zhou, Michael D. Nieves, Nikki M. McCormack, Matthew D. Wilkerson, Gauthaman Sukumar, Clifton L. Dalgard and Martin L. Doughty

    Version of Record online: 12 DEC 2017 | DOI: 10.1002/glia.23278

    Thumbnail image of graphical abstract

    Main Points

    • Human iPS cell-derived NSCs were differentiated to isogenic neurons or astrocytes.
    • Few neurons developed spontaneous activity.
    • Spontaneous activity was significantly increased by neuronal co-culture on mouse but not isogenic human astrocytes.
  2. Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs

    Nizar M. Yousif, Antonio Carlos Pinheiro de Oliveira, Simone Brioschi, Michael Huell, Knut Biber and Bernd L. Fiebich

    Version of Record online: 11 DEC 2017 | DOI: 10.1002/glia.23276

    Thumbnail image of graphical abstract

    Main Points

    • Activation of EP2 mediated diverse anti-inflammatory effects in challenged OHSCs and primary microglia via a mechanism that involve MAPKs.
    • Microglia control TLR3/TLR4 activation and its related inflammatory response in challenged OHSCs.
  3. Fasting induces astroglial plasticity in the olfactory bulb glomeruli of rats

    Virginie Daumas-Meyer, Gaëlle Champeil-Potokar, Catherine Chaumontet, Patrice Dahirel, Catherine Papillon, Patrice Congar and Isabelle Denis

    Version of Record online: 11 DEC 2017 | DOI: 10.1002/glia.23280

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    Main Points

    • Fasting induces astroglial spreading in rat OB glomeruli
    • Restoration of glycemia or the satietogenic PYY3-36 (but not leptin) reverse this morphological plasticity
    • Orexigenic ghrelin and NPY induce the astroglial spreading
  4. You have full text access to this OnlineOpen article
    Myelin extracellular leaflet compaction requires apolipoprotein D membrane management to optimize lysosomal-dependent recycling and glycocalyx removal

    Nadia García-Mateo, Raquel Pascua-Maestro, Alberto Pérez-Castellanos, Concepción Lillo, Diego Sanchez and Maria D. Ganfornina

    Version of Record online: 9 DEC 2017 | DOI: 10.1002/glia.23274

    Thumbnail image of graphical abstract

    Main Points

    • Apolipoprotein D is required for myelin extracellular leaflet compaction.
    • Lack of ApoD halts glycocalyx removal by altering sialidases activity and traffic.
    • Targeting ApoD to lysosomes is sufficient for glial cells to control their glycocalyx.
  5. Bioenergetic regulation of microglia

    Soumitra Ghosh, Erika Castillo, Elma S. Frias and Raymond A. Swanson

    Version of Record online: 8 DEC 2017 | DOI: 10.1002/glia.23271