Cover image for Vol. 64 Issue 8

Edited By: Bruce R. Ransom and Helmut Kettenmann

Impact Factor: 5.997

ISI Journal Citation Reports © Ranking: 2015: 25/256 (Neurosciences)

Online ISSN: 1098-1136

Virtual Issue: Microglia


In the era of paperless offices and electronic handling of scientific manuscripts, we got the idea that the printed Special Issue of Glia should be supplemented by a Virtual Issue. Albeit being labeled as virtual, this accompanying issue is real and comprises a collection of published primary manuscripts, which received great attention and remain of major interest in the field. They cover exciting aspects of microglia biology ranging from microglia diversity in vivo (De Haas et al., 2008), regulation of microglia activation (Choi, et al., 2011; Halleskog et al., 2011; Leying et al., 2011; Suck et al., 2010), their function during development (Cacci et al., 2008), and their role in disease pathology (Holm et al. 2012; Prukup et al. 2010; Thored et al. 2009). In keeping with our notion that a new era of microglial research is upon us, all are recent with the majority appearing in 2010–2012. Although the printed Special Issue on microglia can be considered the main dish for microglia researchers, the Virtual Issue is to be savored as a special dessert. Enjoy the treat!

RICHARD M. RANSOHOFF Neuroinflammation Research Center Lerner Research Institute Cleveland Clinic Cleveland, Ohio 44195

MARCO PRINZ Department of Neuropathology University of Freiburg D-79106 Freiburg, Germany

Evidence for synaptic stripping by cortical microglia
Trapp Bruce D.; Wujek Jerome R.; Criste Gerson A.; et al.
Volume 55, Issue 4, March 2007

Microglia derived from aging mice exhibit an altered inflammatory profile
Sierra Amanda; Gottfried-Blackmore Andres C.; McEwen Bruce S.; et al.
Volume 55, Issue 4, March 2007

In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia
Cacci Emanuele; Ajmone-Cat Maria Antonietta; Anelli Tonino; et al.
Volume 56, Issue 4, March 2008

Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS
De Haas Alexander H.; Boddeke Hendrikus W. G. M.; Biber Knut
Volume 56, Issue 8, June 2008

Steroid hormone receptor expression and function in microglia
Sierra Amanda; Gottfried-Blackmore Andres; Milner Teresa A.; et al.
Volume 56, Issue 6, April 2008

Long-Term Accumulation of Microglia with Proneurogenic Phenotype Concomitant with Persistent Neurogenesis in Adult Subventricular Zone After Stroke
Thored Par; Heldmann Ursula; Gomes-Leal Walace; et al.
Volume 57, Issue 8, June 2009

Foxp3 Is a Novel Repressor of Microglia Activation
Chung Hwan-Suck; Lee Jun-Ho; Kim Hyunseong; et al.
Volume 58, Issue 10, August 2010

Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way

Pukrop Tobias; Dehghani Faramarz; Chuang Han-Ning.; et al
Volume 58, Issue 12, September 2010

S100B Attenuates Microglia Activation in Gliomas: Possible Role of STAT3 Pathway
Zhang Leying; Liu Wei; Alizadeh Darya; et al.
Volume 58, Issue 3, March 2011

Translocator Protein (18 kDa)/Peripheral Benzodiazepine Receptor Specific Ligands Induce Microglia Functions Consistent with an Activated State
Choi Judy; Ifuku Masataka; Noda Mami; et al.
Volume 58, Issue 2, February 2011

WNT Signaling in Activated Microglia Is Proinflammatory
Halleskog Carina; Mulder Jan; Dahlstrom Jenny; et al.
Volume 59, Issue 1, January 2011

Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats
Sanagi Tomomi; Nakamura Yasuko; Suzuki Eri; et al.
Volume 60, Issue 5, May 2012

P2X4 receptor channels form large noncytolytic pores in resting and activated microglia
Bernier Louis-Philippe; Ase Ariel R.; Boue-Grabot Eric; et al.
Volume 60, Issue 5, May 2012'

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar A beta by microglia
Fu Hongjun; Liu Bin; Frost Jeffrey L.; et al.
Volume 60, Issue 6, May 2012

Phagocytosis of neuronal debris by microglia is associated with neuronal damage in multiple sclerosis
Huizinga Ruth; van der Star Baukje J.; Kipp Markus; et al.
Volume 60, Issue 3, March 2012

Microglia are required for astroglial toll-like receptor 4 response and for optimal TLR2 and TLR3 response
Holm Thomas H.; Draeby Dina; Owens Trevor
Volume 60, Issue 4, April 2012