Genes, Chromosomes and Cancer

Cover image for Vol. 56 Issue 4

Edited By: Felix Mitelman

Impact Factor: 3.96

ISI Journal Citation Reports © Ranking: 2015: 38/166 (Genetics & Heredity); 58/213 (Oncology)

Online ISSN: 1098-2264

Author Guidelines

NIH Public Access Mandate
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Author Guidelines

Wiley's Journal Styles

Manuscript Submission

Manuscripts should be submitted via the journal’s online system. To submit your manuscript, please go to and follow the step-by-step instructions. Submission implies that all coauthors have approved the content of the manuscript and its submission by the corresponding author, and that the corresponding author is authorized to represent all coauthors. The corresponding author for editorial purposes need not be the senior author, nor the person to whom correspondence is addressed after publication.

Pre-submission enquiries can be sent to Prof. Felix Mitelman (

All manuscripts submitted to Genes, Chromosomes & Cancer must be submitted solely to this journal and may not have been published in another publication of any type, professional or lay. Upon acceptance of a manuscript for publication, the author will be requested to sign an agreement transferring copyright to the publisher, who reserves copyright. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The Journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors, who will assist the editorial office by reviewing proofs before publication. Reprint order forms will be sent with the proofs.

Manuscript Preparation

Review Articles review a specific field through an appropriate literature survey. An Abstract is required. Materials and Methods and Results sections are not required. Although there are no restrictions on the number of pages or figures, the Review should be as concise as possible. Review articles are usually invited; the editors welcome proposals and suggestions for topics.

Research Articles should report original data and contain sections in the following order: Title Page, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments (optional), References, Tables, and Figure Legends. Use generic names of drugs and give manufacturer, city, and state or country of all trademarked equipment mentioned in the text.

Letters to the Editors comment on a work recently published in the journal. These should be kept brief, in general not longer than one printed page, but may be illustrated. No abstract is required. Authors of the work commented on will be invited to reply in the same issue of the Journal.

Perspective Articles are intended to shed light on general topics in cancer genetics in a manner different from that normally found in Research Articles and Review Articles. They should be provocative and juxtapose lines of reasoning that are conventionally seen as separate, to achieve a deeper understanding of the problems discussed. Perspective Articles are usually invited; the editors welcome proposals and suggestions for topics. An abstract is required.

Format of Manuscript Elements

Title Page. Give a descriptive title with no abbreviations. Provide first and last names of each author and department and institutional affiliations. Give full address of corresponding author and telephone, telex, and FAX numbers and an abbreviated title not to exceed 45 characters. Avoid nonstandard abbreviations; do not abbreviate single words (see "Conventions and Nomenclature").

Abstract. Limit the abstract to a single paragraph of not more that 250 words. It must describe work and include purpose, brief statement of methods, and results. Literature references should not be given in the Abstract. Definitions of abbreviations (see "Conventions and Nomenclature") must be repeated when the abbreviation is used for the first time in the text.

Key Words and Search Engine Optimization. Driving usage and readership is critically important to raising the visibility of your published research. One of the key factors in sustaining long-term usage is through search engine optimization (SEO). Below is a list of suggested ways of maximizing your SEO.

1. Make sure your article title is SEO-friendly. It should be descriptive, and it must include a key phrase from your topic. Key words should appear within the title's first 65 characters.

2. Provide up to five key words or phrases in the keyword field.

3. Be sure your key words and phrases appear in your abstract several times, but don't go overboard or the search engine may kick you out.

4. When referencing authors, be consistent. Use their names as they generally appear in past online publications.

5. When appropriate, use your key words in article section headings.

Remember: They can't read it if they can't find it!

For more detailed information on SEO, including helpful examples, go to

Materials and Methods. Experimental procedures should be described in sufficient detail to enable the work to be repeated. References to other papers describing the techniques may be given. Correct chemical names should be given and strains of organisms, clones, etc. should be specified. The names and addresses for suppliers of uncommon reagents or instruments should be mentioned. Authors should draw attention to any particular chemical or biological hazards that may be involved in carrying out the experiments described. Any relevant safety precautions should be described; if an accepted code of practice has been followed, a reference to the relevant standards should be given.

References. Journal follows AMA reference style.


1. Adkinson N, Yunginger J, Busse W, Bochner B, Holgate S, Middleton F, eds. Middleton’s Allergy: Principles and Practice. 6th ed. St Louis, MO: Mosby; 2003.

2. US Department of Health and Human Services. Understanding and Improving Health and Objectives for Improving Health. Vol 1. 2nd ed. Washington, DC: US Dept of Health and Human Services; 2000.

3. Green M, ed. Bright Futures: National Guidelines for Health Supervision of Infants, Children, and Adolescents. 2nd rev ed. Arlington, VA: national Center for Education in Maternal and child Health; 2002.

Chapter in a book:

4. Solensky R. Drug allergy: desensitization and treatment of reactions to antibiotics and aspirin. In: Lockey P, ed. Allergens and Allergen Immunotherapy. 3rd ed. New York, NY: Marcel Dekker; 2004:585-606.

Book as a part of a series:

5. Brune K, Handwerker HO, eds. Hyperalgesia: Molecular Mechanisms and Clinical Implications. Seattle, WA: IASP Press; 2004. Progress in Pain Research and Management; vol 30.


6. Rainier S, Thomas D, Tokarz D, et al. Myofibrillogenesis regulator 1 gene mutations cause paroxysmal dystonic choreoathetosis. Arch Neurol. 2004;61(7):1025-1029.

7. Keppel K, Pamuk E, Lynch J, et al. Methodologic issues in measuring health disparities. Vital Health Stat 2. 2005;(141):1-16.

8. Crino L, Cappuzzo F. Present and future treatment of advanced mom-small-cell lung cancer. Semin Oncol. 2002;29(3)(suppl 9):9-16.

9. McCormick MC, Kass B, Elixhauser A, Thompson J, Simpson L. Annual report on access to and utilization of health care for children and youth in the United States: 1999. Pediatrics. 2000;105(1, pt 3):219-230.


10. Goode E. Study finds jump in children taking psychiatric drugs. New York Times. January 14, 2003:A21.


11. Underman C. Fully Automatic Segmentation of MRI Brain Images Using Probabilistic Diffusion and a Watershed Scale-Space Approach [master’s thesis]. Stockholm, Sweden: NADA, Royal Institute of Technology; 2001.

Package Inserts:

12. Cialis [package insert]. Indianapolis, IN: Eli Lilly & Co; 2003.


13. Guiliano K, Kapur R, inventors; Cellomics Inc, assignee. System for cell-based screening. US patent 6,875,578. April 5, 2005.

Web sites:

14. International Society for Infectious Diseases. ProMED-mail Web site. Accessed December 6, 2005.


15. Weber KJ, Lee J, Decresce R, Subhasis M, Prinz R. Intraoperative PTH monitoring in parathyroid hyperplasia requires stricter criteria for success. Paper presented at: 25th Annual American Association of Endocrine Surgeons meeting; April 6, 2004; Charlottesville, VA.

16. Khuri FR, Lee JJ, Lippman Sm, et al. Isotretinoin effects on head and neck cancer recurrence and second primary tumors. In: Proceedings from the American Society of Clinical Oncology; May 31-June 3, 2003; Chicago, IL. Abstract 359.

17. Ofri D. Incidental Findings: Lessons from My patients in the Art of medicine. Boston, MA: Beacon Press. In Press.

Tables. All tables must be cited in the text and have titles. Number them consecutively with arabic numerals. Cite each table at the most appropriate point in the text. Tables should present comparisons of data that are too cumbersome to describe in the text; they should not merely repeat text information. Each table should be typed double-spaced on a separate sheet of paper and should include a title and, in a footnote, definitions of all abbreviations used in it (even if abbreviations are defined in the text), indicated by lowercase superscript letters, a, b, c, etc.

Figures. Figures should be numbered in one consecutive series using arabic numerals, and keyed into the text. All original letters, numbers, and symbols must be large enough that, when reduced to journal format (8 1/4 x 11 inch double-column), they will remain at least 2mm high. Each figure requires a corresponding legend; legends should be double-spaced and grouped on a separate page(s). Each legend should describe briefly the information presented; detailed descriptions of procedures should appear in the Materials and Methods section. Abbreviations used in figures and photographs must match exactly those used in the text. Upon acceptance of color illustrations, the publisher will provide price quotes.

Rapid Inspector TM gives authors of scientific, technical, and medical journals a resource for certifying their illustrations prior to submission. Utilizing this software will ensure that your graphics are suitable for print production. To download this journal's free Rapid Inspector software, please visit .

Conventions and Nomenclature. In the description of karyotypes, authors should follow the most recent recommendations of the International Standing Committee on Human Cytogenetic Nomenclature (ISCN). For gene mapping nomenclature, the most recent guidelines of the Human Gene Mapping Nomenclature Committee should be used. Authors should use SI units and follow the guidelines for abbreviations and symbols of the IUPAC-IUB Joint Commission on Biochemical Nomenclature. See Eur J Biochem (1970) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5. All nonstandard abbreviations used in the text should be defined when first used.70) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5.

Authors should use SI units and follow the guidelines for abbreviations and symbols of the IUPAC-IUB Joint Commission on Biochemical Nomenclature. See Eur J Biochem (1970) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5.

Submission of Data to the Genetics Databases. The editorial policy of the journal is to encourage the use of genetics databases (e.g., HGML, GenBank, EMBL) as repositories for detailed DNA sequences and mapping assignments, etc. Authors are encouraged to complete data entry and annotation forms for the appropriate databases, which can be obtained from the databases. Include copies of these summaries and database entries/accession information with the manuscripts at the time of submission. Where possible, published articles will be accompanied by footnotes with accession information for retrieving and cross-referencing data from the genetic information repositories.


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For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

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To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

For RCUK and Wellcome Trust authors click on the link below to preview the terms and conditions of this license:

Creative Commons Attribution License OAA

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