Genes, Chromosomes and Cancer

Cover image for Vol. 55 Issue 9

Edited By: Felix Mitelman

Impact Factor: 3.96

ISI Journal Citation Reports © Ranking: 2015: 38/165 (Genetics & Heredity); 58/213 (Oncology)

Online ISSN: 1098-2264

Author Guidelines

NIH Public Access Mandate
For those interested in the Wiley-Blackwell policy on the NIH Public Access Mandate, please visit our policy statement

For additional tools visit Author Resources - an enhanced suite of online tools for Wiley InterScience journal authors, featuring Article Tracking, E-mail Publication Alerts and Customized Research Tools.

Author Guidelines

Wiley's Journal Styles

Manuscript Submission

Manuscripts should be submitted via the journal’s online system. To submit your manuscript, please go to and follow the step-by-step instructions. Submission implies that all coauthors have approved the content of the manuscript and its submission by the corresponding author, and that the corresponding author is authorized to represent all coauthors. The corresponding author for editorial purposes need not be the senior author, nor the person to whom correspondence is addressed after publication.

Pre-submission enquiries can be sent to Prof. Felix Mitelman (

All manuscripts submitted to Genes, Chromosomes & Cancer must be submitted solely to this journal and may not have been published in another publication of any type, professional or lay. Upon acceptance of a manuscript for publication, the author will be requested to sign an agreement transferring copyright to the publisher, who reserves copyright. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The Journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors, who will assist the editorial office by reviewing proofs before publication. Reprint order forms will be sent with the proofs.

Manuscript Preparation

Review Articles review a specific field through an appropriate literature survey. An Abstract is required. Materials and Methods and Results sections are not required. Although there are no restrictions on the number of pages or figures, the Review should be as concise as possible. Review articles are usually invited; the editors welcome proposals and suggestions for topics.

Research Articles should report original data and contain sections in the following order: Title Page, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments (optional), References, Tables, and Figure Legends. Use generic names of drugs and give manufacturer, city, and state or country of all trademarked equipment mentioned in the text.

Letters to the Editors comment on a work recently published in the journal. These should be kept brief, in general not longer than one printed page, but may be illustrated. No abstract is required. Authors of the work commented on will be invited to reply in the same issue of the Journal.

Perspective Articles are intended to shed light on general topics in cancer genetics in a manner different from that normally found in Research Articles and Review Articles. They should be provocative and juxtapose lines of reasoning that are conventionally seen as separate, to achieve a deeper understanding of the problems discussed. Perspective Articles are usually invited; the editors welcome proposals and suggestions for topics. An abstract is required.

Format of Manuscript Elements

Title Page. Give a descriptive title with no abbreviations. Provide first and last names of each author and department and institutional affiliations. Give full address of corresponding author and telephone, telex, and FAX numbers and an abbreviated title not to exceed 45 characters. Avoid nonstandard abbreviations; do not abbreviate single words (see "Conventions and Nomenclature").

Abstract. Limit the abstract to a single paragraph of not more that 250 words. It must describe work and include purpose, brief statement of methods, and results. Literature references should not be given in the Abstract. Definitions of abbreviations (see "Conventions and Nomenclature") must be repeated when the abbreviation is used for the first time in the text.

Key Words and Search Engine Optimization. Driving usage and readership is critically important to raising the visibility of your published research. One of the key factors in sustaining long-term usage is through search engine optimization (SEO). Below is a list of suggested ways of maximizing your SEO.

1. Make sure your article title is SEO-friendly. It should be descriptive, and it must include a key phrase from your topic. Key words should appear within the title's first 65 characters.

2. Provide up to five key words or phrases in the keyword field.

3. Be sure your key words and phrases appear in your abstract several times, but don't go overboard or the search engine may kick you out.

4. When referencing authors, be consistent. Use their names as they generally appear in past online publications.

5. When appropriate, use your key words in article section headings.

Remember: They can't read it if they can't find it!

For more detailed information on SEO, including helpful examples, go to

Materials and Methods. Experimental procedures should be described in sufficient detail to enable the work to be repeated. References to other papers describing the techniques may be given. Correct chemical names should be given and strains of organisms, clones, etc. should be specified. The names and addresses for suppliers of uncommon reagents or instruments should be mentioned. Authors should draw attention to any particular chemical or biological hazards that may be involved in carrying out the experiments described. Any relevant safety precautions should be described; if an accepted code of practice has been followed, a reference to the relevant standards should be given.


The accuracy of references is the responsibility of the authors. Only published articles and those in press may be included in the reference list. Unpublished data and submitted manuscripts, but not meeting abstracts, must be cited parenthetically within the text. Personal communications should also be cited within the text; permission in writing from the communicator is required to publish the information. In the text, references to the literature should be made by author's name followed by year of publication arranged chronologically and then alphabetically. When there are more than two authors, use the first author's name and et al. When references are made to more than one paper by the same author, published in the same year, they are to be designated as a, b, etc.

In the reference list, references are to be arranged alphabetically listing all authors, and then by year of publication. Journal titles should be abbreviated according to Index Medicus; the titles of unindexed journals should be spelled out in full. Use the following style when preparing references.

Duan F, Smith LM, Gustafson DM, Zhang C, Dunlevy MJ, Gastier-Foster, Barr FG. 2012. Genomic and clinical analysis of fusion gene amplification in rhabdomyosarcoma: A report from the Children’s Oncology Group. Genes Chromosomes Cancer 51:662-674.

Book Chapter:
de Alava E, Lessnick SL, Sorensen PH. 2013. Ewing sarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, editors. WHO classification of tumors of soft tissue and bone. Lyon: IARC. p 305-309.

Heim S, Mitelman F. 2009. Cancer cytogenetics. 3rd ed. New York: Wiley-Blackwell. 736 p.

Tables. All tables must be cited in the text and have titles. Number them consecutively with arabic numerals. Cite each table at the most appropriate point in the text. Tables should present comparisons of data that are too cumbersome to describe in the text; they should not merely repeat text information. Each table should be typed double-spaced on a separate sheet of paper and should include a title and, in a footnote, definitions of all abbreviations used in it (even if abbreviations are defined in the text), indicated by lowercase superscript letters, a, b, c, etc.

Figures. Figures should be numbered in one consecutive series using arabic numerals, and keyed into the text. All original letters, numbers, and symbols must be large enough that, when reduced to journal format (8 1/4 x 11 inch double-column), they will remain at least 2mm high. Each figure requires a corresponding legend; legends should be double-spaced and grouped on a separate page(s). Each legend should describe briefly the information presented; detailed descriptions of procedures should appear in the Materials and Methods section. Abbreviations used in figures and photographs must match exactly those used in the text. Upon acceptance of color illustrations, the publisher will provide price quotes.

Rapid Inspector TM gives authors of scientific, technical, and medical journals a resource for certifying their illustrations prior to submission. Utilizing this software will ensure that your graphics are suitable for print production. To download this journal's free Rapid Inspector software, please visit .

Conventions and Nomenclature. In the description of karyotypes, authors should follow the most recent recommendations of the International Standing Committee on Human Cytogenetic Nomenclature (ISCN). For gene mapping nomenclature, the most recent guidelines of the Human Gene Mapping Nomenclature Committee should be used. Authors should use SI units and follow the guidelines for abbreviations and symbols of the IUPAC-IUB Joint Commission on Biochemical Nomenclature. See Eur J Biochem (1970) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5. All nonstandard abbreviations used in the text should be defined when first used.70) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5.

Authors should use SI units and follow the guidelines for abbreviations and symbols of the IUPAC-IUB Joint Commission on Biochemical Nomenclature. See Eur J Biochem (1970) 15:203-208; corrected (1972) 25:1-4. For bases in nucleic acid sequences, see Eur J Biochem (1985) 150:1-5.

Submission of Data to the Genetics Databases. The editorial policy of the journal is to encourage the use of genetics databases (e.g., HGML, GenBank, EMBL) as repositories for detailed DNA sequences and mapping assignments, etc. Authors are encouraged to complete data entry and annotation forms for the appropriate databases, which can be obtained from the databases. Include copies of these summaries and database entries/accession information with the manuscripts at the time of submission. Where possible, published articles will be accompanied by footnotes with accession information for retrieving and cross-referencing data from the genetic information repositories.


If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

For RCUK and Wellcome Trust authors click on the link below to preview the terms and conditions of this license:

Creative Commons Attribution License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

??? Production Questions ???
Production Editor