Environmental and Molecular Mutagenesis

These Editor's Choice articles are specially selected and made available free to read online or download:

May 2013
Catalase has a key role in protecting cells from the genotoxic effects of monomethylarsonous acid: A highly active metabolite of arsenic
Jorge G. Muñiz Ortiz et al

April 2013
The pesticide dichlorvos disrupts mitotic division by delocalizing the kinesin Kif2a from centrosomes
Mario Fiore et al

March 2013
Building on the past, shaping the future: The environmental mutagenesis and genomics society
Thomas E. Wilson et al

Evaluation of gene expression changes in human primary uroepithelial cells following 24-Hr exposures to inorganic arsenic and its methylated metabolites
Janice W. Yager et al

January 2013
Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease
Arthur P. Grollman

Read more Editor's Choice articles.

Environmental and Molecular Mutagenesis is delighted to announce its 2011 Impact Factor* 3.709!

*2011 Journal Citation Reports® (Thomson Reuters, 2011)
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Special issue on DNA polymerases and maintenance of genomic stability

The maintenance of genome integrity depends upon accurate DNA synthesis during DNA replication, DNA repair, and recombination. Mutagenesis is an active cellular process, and numerous types of mutations and chromosomal rearrangements are the direct result of DNA polymerase errors. The December 2012 Special Issue of Environmental and Molecular Mutagenesis presents a collection of original and review articles describing the myriad of DNA polymerases that are required to maintain genome stability. Evidence from several areas of mutagenesis research is presented, all of which suggest that multiple polymerases cooperate in a particular genome maintenance pathway. The issue highlights the importance of DNA polymerases for both generating somatic diversity and maintaining genetic stability, as well as the disease consequences of aberrant DNA polymerase function and/or regulation. The special issue format was inspired by a symposium at the Environmental Mutagen Society’s 2011 Annual Meeting, entitled “The Multiplicity of DNA Polymerases: A Strategy for Maintaining Genome Stability”.

Read more of this Special Issue on DNA polymerases and maintenance of genomic stability.