Synapse

Cover image for Vol. 72 Issue 3

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Henrique von Gersdorff

Impact Factor: 2.132

ISI Journal Citation Reports © Ranking: 2016: 184/259 (Neurosciences)

Online ISSN: 1098-2396

VIEW

  1. 1 - 7
  1. RESEARCH ARTICLES

    1. Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels

      John Hamilton, Matthew Marion, Antonio Figueiredo, Brendan H. Clavin, Dale Deutsch, Martin Kaczocha, Samir Haj-Dahmane and Panayotis K. Thanos

      Version of Record online: 19 FEB 2018 | DOI: 10.1002/syn.22031

      Thumbnail image of graphical abstract
      • FABP did not have effects on acquisition of cocaine conditioned place preference.
      • FABP 5/7 KO mice (unlike wild type mice) did not show stress-induced reinstatement of cocaine place preference.
      • This result may be attributed to a reduced stress corticosterone response in the FABP 5/7 KO mice.
    2. Reference tissue models in the assessment of 11C-DTBZ binding to the VMAT2 in rat striatum: A test-retest reproducibility study

      Arturo Avendaño-Estrada and Miguel Angel Ávila-Rodríguez

      Version of Record online: 7 FEB 2018 | DOI: 10.1002/syn.22029

      Thumbnail image of graphical abstract

      Reproducibility and reliability of reference tissue-based methods was evaluated to determine the nondisplaceable binding potential (BPND) as a quantitative measure of 11C-DTBZ binding to the presynaptic vesicular monoamine transporter 2 (VMAT2) in rat striatum. MRTM2 and SRTM showed the best repeatability and accuracy indices followed by MRTMo, LRTM, and SCR-1.

    3. Crocin improved amyloid beta induced long-term potentiation and memory deficits in the hippocampal CA1 neurons in freely moving rats

      Mohammadmehdi Hadipour, Gholamreza Kaka, Farideh Bahrami, Gholam Hossein Meftahi, Gila Pirzad Jahromi, Alireza Mohammadi and Hedayat Sahraei

      Version of Record online: 2 FEB 2018 | DOI: 10.1002/syn.22026

      Thumbnail image of graphical abstract
      • Bilaterally beta-amyloid (Aβ) administration into the frontal cortex increased memory deficit, which intraperitoneal injection of crocin significantly improved Aβ-induced spatial memory impairment.
      • Crocin treatment significantly attenuates c-Fos level and neuronal apoptosis in hippocampus induced by Aβ administration into the frontal cortex.
      • Crocin antagonizes the blocking effect of Aβ-induced LTP deficits in freely moving rat.
    4. Quantifying the effect of light activated outer and inner retinal inhibitory pathways on glutamate release from mixed bipolar cells.

      Mikhail Y Lipin and Jozsef Vigh

      Version of Record online: 2 FEB 2018 | DOI: 10.1002/syn.22028

      Thumbnail image of graphical abstract

      Functional characterization of amacrine cell-mediated, GABAergic inner retinal and horizontal cell-mediated, non-GABAergic outer retinal inhibitory processes was performed by quantifying their efficiency of inhibiting light-evoked glutamate release from the axon terminals of Mb type bipolar cells at various stimulus intensities.

    5. Characterization of a 3xTg-AD mouse model of Alzheimer's disease with the senescence accelerated mouse prone 8 (SAMP8) background

      Jessica Virgili, Meryem Lebbadi, Cyntia Tremblay, Isabelle St-Amour, Caroline Pierrisnard, Audrey Faucher-Genest, Vincent Emond, Carl Julien and Frédéric Calon

      Version of Record online: 1 FEB 2018 | DOI: 10.1002/syn.22025

      Thumbnail image of graphical abstract

      Heterozygous female 3xTg-AD mice with senescence-accelerated prone 8 (SAMP8) background displayed a more severe AD-like neuropathology compared to senescence-resistant-1 (SAMR1) controls.

    6. Different effects of chronic THC on the neuroadaptive response of dopamine D2/3 receptor-mediated signaling in roman high- and roman low-avoidance rats

      Benjamin B. Tournier, Andrea Dimiziani, Stergios Tsartsalis, Philippe Millet and Nathalie Ginovart

      Version of Record online: 10 JAN 2018 | DOI: 10.1002/syn.22023

      Thumbnail image of graphical abstract

      Using ex vivo measures of [18F]Fallypride and [3H]-(+)-PHNO bindings and the psychomotor response to quinpirole, we found that chronic THC induces a neurochemical and functional supersensitivity of striatal dopamine D2/3 receptors in the psychostimulant-resistant RLA rats. In contrast, the high psychostimulant-responsive RHA rats appeared resistant to the THC-induced neuroadaptive changes in D2/3 receptors.

    7. Juvenile social experience and differential age-related changes in the dendritic morphologies of subareas of the prefrontal cortex in rats

      Brett T. Himmler, Richelle Mychasiuk, Ayuno Nakahashi, Stephanie M. Himmler, Sergio M. Pellis and Bryan Kolb

      Version of Record online: 21 DEC 2017 | DOI: 10.1002/syn.22022

      Thumbnail image of graphical abstract

      The structure of neurons in orbital prefrontal cortex is modified by social housing in an age- and housing-dependent manner. This suggests that the degree of pruning depends on both the age and the specific functional demands of the areas involved.

VIEW

  1. 1 - 7

SEARCH

SEARCH BY CITATION