Molecular Reproduction and Development

Cover image for Vol. 84 Issue 12

Edited By: Gary M. Wessel

Impact Factor: 2.316

ISI Journal Citation Reports © Ranking: 2016: 18/29 (Reproductive Biology); 21/41 (Developmental Biology); 137/190 (Cell Biology); 185/290 (Biochemistry & Molecular Biology)

Online ISSN: 1098-2795

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Author Guidelines

Gene names
Materials Release
Dataset accessibility
Research with vertebrates and humans
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MRD publishes several types of submissions:
Visions: The Art of Science
Reviews and Essays
Research Articles


1. Online submission is required at If you have not already done so, create an account for yourself in the system by clicking on the "Create an Account" button. Please study the site's Instructions and Forms, and then let the system guide you through the submission process. If you have any questions, online help is available to you at .

2. Files uploaded to MRD's online submission system are ultimately used in final production through a completely paperless system. We therefore ask for production-quality files at submission. The manuscript preparation guidelines below must be followed, otherwise manuscripts will be returned to the author without review.

3. All text pages must be double-spaced and have one-inch margins, including the abstract, text, references, and legends. Number all pages in sequence, beginning with the title page.

All Manuscripts submitted to Molecular Reproduction and Development must be submitted solely to this journal, may not have been published in any part or form (except as an abstract for a meeting) in another publication of any type, professional or lay, and become the property of the publisher. Claims of novelty in data or methods should be phrased in ways that indicate how the field will be advanced by the results presented. Upon acceptance of a manuscript for publication, the author will be required to sign an agreement transferring copyright to the publisher, who reserves copyright. No published material may be reproduced or published elsewhere without the written permission of the publisher and the author. The journal will not be responsible for the loss of manuscripts at any time. All statements in, or omissions from, published manuscripts are the responsibility of the authors, who will review proofs thoroughly before publication. No page charges will be levied against authors or their institutions for publication in the journal.

Reprints: Reprints may be purchased at

Authors in Japan please note: Wiley-Japan can provide authors in Japan with a list of recommended services to check and improve the English of their papers before submission. Please visit for more information.

Authors in China please note: Authors in China can visit the Author Resources site on for additional resources, including tips for English writing skills, and bilingual, short presentations on different topics of interest.


Molecular Reproduction and Development is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE) (

Conflict of Interest

Molecular Reproduction and Development requires that all authors disclose any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, that might be perceived as influencing an author’s objectivity is considered a potential source of conflict of interest. These must be disclosed when directly relevant or indirectly related to the work that the authors describe in their manuscript. Potential sources of conflict of interest include but are not limited to patent or stock ownership, membership of a company board of directors, membership of an advisory board or committee for a company, and consultancy for or receipt of speaker’s fees from a company. The existence of a conflict of interest does not preclude publication in this journal. If the authors have no conflict of interest to declare, they must also state this at submission. It is the responsibility of the corresponding author to review this policy with all authors and to collectively list in the cover letter (if applicable) to the Editor-in-Chief, in the manuscript (in the footnotes, Conflict of Interest or Acknowledgments section), and in the online submission system ALL pertinent commercial and other relationships.


VISIONS: The Art of Science
“VISIONS: The Art of Science” highlights the visual impact inherent in the field of reproduction and development. Researchers are encouraged to submit individual figures of visual scientific interest that convey important concepts or lessons without requiring significant text for this section of the journal. Each image should be submitted through the ScholarOne Manuscripts website. Figure formatting must be at least 22 x 28 cm at a resolution of 600 dpi, and must include a title and a legend of less than 250 words that describes the image sufficiently to be understood by a broad audience of researchers. The Editorial Board will evaluate these submissions for their visual impact and scientific content. These publications are free of page and color figures charges and will be freely and immediately available upon acceptance for the widest possible distribution of your work.

CORRESPONDENCE is a section of short, one journal page (500 words or less, or about one column length total) communication for the research field. This section is devoted to short research results, announcements of interest to the community, new databases or software program availability, or other research results not appropriate for full-length papers. A single figure may be included when essential, but these figures will be published at no larger than one column width squared (9 x 9 cm), inclusive of the figure legend text. CORRESPONDENCES should start with one-to-two sentences of introduction or integration into the major point of the communication, and end with the major conclusion obtained. Up to three references may be included (not part of the 500 word limit), with formatting as below for Manuscripts. CORRESPONDENCES should be submitted through the ScholarOne Manuscripts website. These submissions are evaluated by the Editorial Board and by external reviewers. At the Editors discretion, CORRESPONDENCE can be published with expanded size (in two journal pages): 1000 words, two figures, and six references. These publications are free of page charges (including color figures) and will be immediately available upon acceptance for the widest possible distribution of your work. If the author wishes to have the print version of this type of manuscript published in color, a charge of $250 per figure will be levied.

Submissions of REVIEWS and ESSAYS are encouraged. The topics of the manuscript are flexible, but they are intended to reach a broad audience of readers in molecular reproduction and development—from investigators in the field, to students learning the material for the first time. Therefore, it is important that the reviews start generally or with a historical perspective to integrate the topic into a larger context. The bulk of the review should be a critical analysis of the current field and should end with important yet-unresolved questions, speculations, and directions for the field in the future. All other formats for the review are as listed below for manuscripts. ESSAYS follow a similar guideline, but the topics may be more speculative, of historical emphasis, or may integrate more than scientific content. These publications are free of page charges (including color figures) and will be immediately available upon acceptance for the widest possible distribution of your work.

Molecular Reproduction and Development is an international journal devoted to an integrated approach towards understanding the dynamic continuum of reproductive and developmental processes. As such, the journal is interested in RESEARCH ARTICLES that advance the field by mechanistic discoveries, and by functional understanding. Manuscripts reporting purely descriptive science must be of particular interest to be considered for the journal. MRD particularly encourages manuscripts with a convergence of disciplines, including systems biology, computational modeling, nanoscience, organic chemistry, bioengineering, evolutionary and synthetic biology — all within the framework that describes or reveals a mechanistic aspect of reproduction and development. These submissions are evaluated by the Editorial Board and by external reviewers in accordance with the Peer Review Policy of MRD (see These publications are free of page charges (including color figures) and will be immediately available upon acceptance for the widest possible distribution of your work. If the author wishes to have the print version of this type of manuscript published in color, a charge of $250 per figure will be levied.


1. Title page. The manuscript should have an informative title that defines the major findings described within the work. The title page must include the names and affiliations of all authors, the institution at which the work was performed, the name and address for all correspondence, telephone, telex, or fax number must be present. Include a short title of not more than 40 characters to be used as a Running Head, and three-to-six Keywords (not used in the title), which will appear below the abstract. Abbreviations used in the manuscript must be listed, and grants that support the work in the manuscript should be clearly acknowledged here.

2. Abstract. This section should be a factual condensation of the entire work and should include statements of the problem, methods of study, results, and conclusions as appropriate. All quantitative data in the abstract must also appear in the manuscript text or tables. The abstract may not exceed 250 words.

3. Text. Text of Research Articles should follow the format: Introduction, Results, Discussion, Materials and Methods, Acknowledgments, References, and Figure Legends. All sections should be concise, and the manuscript as a whole should avoid unnecessary repetition of citations, ideas, or data. In particular, Discussion sections should clearly place the data into context and address the question of how the field is advanced by these finding; paraphrasing or reiterating the Results in more than a short paragraph within the Discussion section is discouraged.

If the work includes data derived from human subjects, a statement that informed, written consent was obtained is mandatory. Use subheadings and paragraph titles whenever possible. Authors should ensure that clear and idiomatic English is used prior to submission. All uncommon abbreviations must be defined. Please see below for guidelines on accepted gene symbol and nomenclature use.

Abbreviate measurements (cm, ml) according to Style Manual for Biological journals, American Institute for Biological Sciences, 3900 Wisconsin Avenue, N.W., Washington, D.C. Place acknowledgments as the last element of the text, before references. Submit your text in DOC, DOCX, or RTF format. Do not embed figures or tables in this document; submit figures and tables as separate files.  Also, see “Additional information and data handling” for studies involving vertebrates and/or humans.

Revisions, when requested, should not contain tracking within the main document(s). If tracking is requested by the handling Editor, a separate version containing tracking should be uploaded as a supplemental file for review.

4. References. The accuracy of references is the responsibility of the authors. Only published papers and those in press may be included in the reference list. Unpublished data and submitted manuscripts must be cited parenthetically within the text. Personal communications should also be cited within the text; permission in writing from the communicator is required.

References should be prepared according to the Publication Manual of the American Psychological Association (6th edition). The APA website includes a range of resources for authors learning to write in APA style, including an overview of the manual, free tutorials on APA Style basics, and an APA Style Blog. For more information about APA referencing style, please also refer to the APA FAQ.

EndNote users can download the style here.

According to APA style, in text citations should follow the author-date method whereby the author's last name and the year of publication for the source should appear in the text, for example, (Jones, 1998). The complete reference list should appear alphabetically by name at the end of the paper.

Authors should note that the APA referencing style requires that a Digital Object Identifier (DOI) be provided for all references where available. Also, for journal articles, issue numbers are not included unless each issue in the volume begins with page one.

5. Legends. A descriptive legend completes an illustration and permits it to be useful without reference to the text. A legend must accompany each illustration and must define any abbreviations used therein. Legends must be typed double spaced on a separate list at the end of the manuscript.   

6. Tables. Each table must have a self-explanatory title, be numbered in order of appearance with Arabic numerals, and be keyed into the text (e.g., in MS Word table format). Tables must be submitted as separate MS Word files with the titles and legends included.

7. Figures. All figures must be numbered in order of appearance in the text with Arabic numerals, and text should be in a legible size. Preferable fonts for the labeling sub-panels include Arial or Helvetica. Figures should be submitted as close to final print size as possible. The maximum width for single-column figures is 8.0 cm (3.1 in.) and for double-column figures is 17.5 cm (6.9 in), and the maximum length is 19.5 cm (7.7 in). For proper conversion into PDF form for review, figures cannot exceed 40 megapixels (length x width, in pixels) and individual files must be less than 200 MB in size. The total submission cannot exceed 350 MB in size. We recommend saving TIFF files with LZW compression to reduce the file sizes prior to submission. Figure resolution information is as follows:

Illustrations. To ensure the highest quality print production, upload figures as separate image files using TIFF or EPS formats only. Images should follow the minimum resolutions: 1200 dpi for black and white line art (simple bar graphs, charts, etc.); 600 dpi for combination halftones (black and white images that also contain labeling or thin lines). Figures created in Adobe Illustrator should be submitted in EPS format. Color Illustrations.Authors are encouraged to submit color illustrations that highlight the text and convey essential scientific information. Color figures should be submitted in a CMYK colorspace, and in at least 600 dpi. All color figures will be reproduced in full color in the online edition of the journal at no cost to authors. If the author wishes to have the print version of Research and Correspondence manuscripts printed in color, a charge of $250 per figure will be levied.

Guidelines for Cover Submissions If you are interested in submitting an original image or graphic from or related to your accepted article for consideration on the cover of the journal, please follow these guidelines.


Nomenclature. Gene names and usage should follow standard, current nomenclature established for the organism referenced in the context of the sentence (please see as a main reference). An example for the insulin gene (or the closest ortholog) is in the first table followed by examples for piwi gene orthologs in the second table. The sites that follow should be used as the definite reference:

Gene symbolmRNAProtein
primates and humansINSINSINS
domestic species (cow, pig, etc)INSINSINS
rodents (mouse, rat, etc.)InsInsINS
birds (chicken, etc.)InsInsINS
amphibians (frog, etc.)InsInsIns
fish (zebrafish, etc.)InsInsIns
insects (flies, mosquito, etc.)Ilp1Ilp1Ilp1
worms (nematodes)Ins-1Ins-1INS-1

Gene symbolmRNAProtein
frog (Xenopus)XiwiXiwiXiwi

Reference sites by organism include: (humans, non-human primates, domestic species) (mice, rats) (chicken) (Xenopus) (zebrafish) (echinoderms) (fruitflies) (nematodes)

Materials release. As a condition for the publication of a manuscript in MRD, the authors must make the relevant materials used to generate the results of the paper freely available to other investigators. The requests must be within reason taking into account cost of production, limited supply, and expenses in shipping. Materials held by a third party distributor should be documented in the manuscript.

Dataset accessibility. All datasets used in manuscripts for MRD must be publically available, either in the manuscript itself, or deposited in publically available databases e.g. GenBank, EMBL – Bank, Data Bank of Japan, miRBase, etc. in compliance with their nomenclature. Manuscripts generating and/or using such datasets should not be published without the corresponding links. A partial listing of such databases follows:

Research with vertebrates and humans.  Research involving live vertebrates, experiments must comply with all relevant institutional and national animal welfare laws, guidelines and policies and/or be conducted under guidelines approved by an Institutional Animal Care and Use Committee or equivalent body and performed in accordance with the NIH and National Research Council's publication “Guide for Care and Use of Laboratory Animals”. The institutional committee(s) overseeing such guidelines must be identified in the Materials and Methods section of the manuscript. If the work includes data derived from human subjects, a statement that informed, written consent was obtained is mandatory and should be submitted with the cover letter. Authors must list the institutional committee(s) that have approved experiments involving human subjects or human tissue in the Materials and Methods section of their paper and include with their submission a statement to confirm that informed consent was obtained from all subjects or tissue donors.

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