European Journal of Inorganic Chemistry

Cover image for Vol. 2016 Issue 26

Editor: Karen Hindson, Deputy Editor: Preeti Vashi

Impact Factor: 2.686

ISI Journal Citation Reports © Ranking: 2015: 12/46 (Chemistry Inorganic & Nuclear)

Online ISSN: 1099-0682

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemCatChem, Zeitschrift für anorganische und allgemeine Chemie

Cover Picture: Complex Formation of ICL670 and Related Ligands with FeIII and FeII (Eur. J. Inorg. Chem. 20/2004)

2004_21/2004The cover picture shows the structure of the FeIII-selective chelating agent ICL670 (R = COOH). ICL670 has a high potential for the oral treatment of iron overload, a condition that originates from regular blood transfusions, as are necessary in the treatment of β-Thalassaemia. However, a possible problem arising from this treatment is the production of OH· radicals, which can be catalysed by redox-cycling of labile FeII/FeIII species. For a conclusive consideration of potential oxidative stress, a careful elucidation of the stability and redox properties of the various FeII/FeIII species, which are present at physiological conditions, has been performed. Details are discussed in the article by K. Hegetschweiler et al. on p. 4177 ff.

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