European Journal of Inorganic Chemistry

Cover image for Vol. 2014 Issue 25

Editor: Karen Hindson, Deputy Editor: Preeti Vashi

Impact Factor: 2.965

ISI Journal Citation Reports © Ranking: 2013: 10/44 (Chemistry Inorganic & Nuclear)

Online ISSN: 1099-0682

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemCatChem, Zeitschrift für anorganische und allgemeine Chemie

2014_25/2014Phosphate Diester Cleavage, DNA Interaction and Cytotoxic Activity of a Bimetallic Bis(1,4,7-triazacyclononane) Zinc Complex (Eur. J. Inorg. Chem. 25/2014)

The cover picture shows the X-ray structure of the dinuclear zinc complex [Zn2{bcmp(-H)}(μ-Cl)](ClO4)2·H2O, where bcmp is the phenolate scaffold ligand 2,6-bis(1,4,7-triazacyclonon-1-ylmethyl)-4-methylphenolate. The complex converts supercoiled plasmid DNA into the nicked form at low micromolar concentration under physiological conditions and shows promising in vitro antitumor activity against pancreatic and lung cancer cell lines. Details are discussed in the article by D. Montagner, A. Erxleben et al. on p. 4084 ff. For more on the story behind the cover research, see the Cover Profile.

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