European Journal of Organic Chemistry
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Organic Chemistry Meets Life Sciences
The European Journal of Organic Chemistry covers all aspects of organic chemistry, including the exciting interface to the life sciences. Read the latest articles:
Viktor O. Iaroshenko, Sergii Dudkin, Vyacheslav Ya. Sosnovskikh, Alexander Villinger, Peter Langer
(β-D-Ribofuranosyl)formamidine in the Design and Synthesis of 2-(β-D-Ribofuranosyl)pyrimidines, Including RF-Containing Derivatives [Full Paper]
Eur. J. Org. Chem.2013, 3166–3173.
Eva Schütznerová, Allen G. Oliver, Jaroslav Zajíček, Viktor Krchnák
Polymer-Supported Stereoselective Synthesis of (1S,5S)-6-Oxa-3,8-diazabicyclo[3.2.1]octanes [Full Paper]
Eur. J. Org. Chem.2013, 3158–3165.
Vladimir S. Yarmolchuk, Oleg V. Shishkin, Viktoriia S. Starova, Olga A. Zaporozhets, Olga Kravchuk, Sergey Zozulya, Igor V. Komarov, Pavel K. Mykhailiuk
Synthesis and Characterization of β-Trifluoromethyl-Substituted Pyrrolidines [Full Paper]
Eur. J. Org. Chem.2013, 3086–3093.
Recently Published Articles
- Synthetic Access to Hydrogen and Halogen Derivatives of 3-Amino-4-nitrothiophenes
Eva-Janina Vogt, Viktor A. Zapol'skii, Eva Nutz and Dieter E. Kaufmann
Article first published online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300006
Starting from per-substituted 3-amino-4-nitrothiophenes with a 2-chloro- and a 5-vinylsulfanyl substituent the formation of vinyl-S-oxides and subsequent substitution against nucleophiles is reported. Additionally, dehalogenation of the formed halothiophenes is possible with three different methods, which lead to selective dehalogenation at the 2, 5 or 2 and 5 position.
- Bile Acid Derived Tropos Vaulted Binaphthylphosphites: Synthesis, Stereochemical Characterization and Complexation to Rhodium
Varsha R. Jumde and Anna Iuliano
Article first published online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300024
Chirality transfer from the cholestanic backbone of bile acid derivatives to the flexible 2,2′-binaphthyl-1,1′-diylphosphite moiety was obtained in the synthesis of three different phosphite ligands.
- Optically Active Monoacylglycerols: Synthesis and Assessment of Purity
Chao-Yuan Chen, Wei-Bo Han, Hui-Jun Chen, Yikang Wu and Po Gao
Article first published online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300247
Because of facile acyl migrations, the synthesis of enantiopure 1(or 3)-acyl-sn-glycerols is much more difficult than their seemingly very simple structures may imply. Even assessment of their optical purity is a difficult task because of the lack of a feasible means of analysis. Now, new findings have changed everything.
- Synthesis of Alkyl-Ynol-Ethers by “Anti-Michael Addition” of Metal Alkoxides to β-Substituted Alkynylsulfones
Leyre Marzo, Alejandro Parra, María Frías, José Alemán and José Luis García Ruano
Article first published online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300395
Ynol ethers can be directly obtained under mild conditions by reaction of KOR with β-substituted 2(-p-tolylsulfonyl)acetylenes. Only arylacetylenes (with KOtBu) and TIPS-acetylenes provide good yields of alkyl ethynyl ethers
- Organic and Organometallic Derivatives of Propargylallene: Syntheses, Structures, Reactivity and Rearrangements
Michael J. McGlinchey and Henning Hopf
Article first published online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300250
Propargylallenes offer varied reactivity patterns arising from the presence of two different multiple bond linkages, either separately or in concert. We review their syntheses, structures, rearrangement mechanisms and synthetic utility, together with their behaviour on treatment with transition-metal reagents such as gold(I), silver(I), platinum metals or metal carbonyls.