European Journal of Organic Chemistry

Cover image for Vol. 2012 Issue 16

Edited By: Haymo Ross, Deputy Editors: Jennifer O'Donnell, Robert Temme

Online ISSN: 1099-0690

Associated Title(s): Advanced Synthesis & Catalysis, Asian Journal of Organic Chemistry

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Organic Chemistry Meets Life Sciences

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Organic Chemistry Meets Life Sciences

The European Journal of Organic Chemistry covers all aspects of organic chemistry, including the exciting interface to the life sciences. Read the latest articles:

Ahmed Khalil, Christophe Mathé, Christian Périgaud
Synthesis of 2',3'-Dideoxy-2'-fluoro-3'-(hydroxyimino)-, -3'-(methoxyimino)- and -3'-(hydroxyamino)pyrimidine Nucleosides [Full Paper]
Eur. J. Org. Chem.2012, 3172–3179.
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Frances Heaney
Nitrile Oxide/Alkyne Cycloadditions – A Credible Platform for Synthesis of Bioinspired Molecules by Metal-Free Molecular Clicking [Microreview]
Eur. J. Org. Chem.2012, 3043–3058.
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Kwok-Kong Tony Mong, Yu-Fang Yen, Wei-Cheng Hung, Yen-Hsun Lai, Jiun-Han Chen
Application of 2-Azido-2-deoxythioglycosides for β-Glycoside Formation and Oligosaccharide Synthesis [Full Paper]
Eur. J. Org. Chem.2012, 3009–3017.
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Recently Published Articles

  1. Oxidative Ring Opening of 1,3-Diaryl­benzo[c]heterocycles Using m-CPBA: Preparation of 1,2-Diaroylbenzenes

    Meganathan Nandakumar, Ramakrishnan Sivasakthikumaran and Arasambattu K. Mohanakrishnan

    Article first published online: 23 MAY 2012 | DOI: 10.1002/ejoc.201200311

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    An efficient procedure for the preparation of a variety of unsymmetrical 1,2-diaroylbenzenes was achieved at room temperature through a m-CPBA-mediated oxidative cleavage of benzo[c]furan analogs. The oxidative ring-opening reaction with benzo[c]thiophene and benzo[c]selenophene analogs was also successful.

  2. Recyclable Hybrid Silica-Based Catalysts Derived from Pd–NHC Complexes for Suzuki, Heck and Sonogashira Reactions

    Guadalupe Borja, Amàlia Monge-Marcet, Roser Pleixats, Teodor Parella, Xavier Cattoën and Michel Wong Chi Man

    Article first published online: 23 MAY 2012 | DOI: 10.1002/ejoc.201200205

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    New hybrid silica materials derived from NHC-palladium complexes have been prepared by a sol-gel process and efficiently applied as recyclable catalysts in C–C coupling reactions.

  3. Enantioselective Asymmetric Michael Addition of Cyclic Diketones to β,γ-Unsaturated α-Keto Esters

    Yi-Feng Wang, Ke Wang, Wei Zhang, Bin-Bin Zhang, Chi-Xiao Zhang and Dan-Qian Xu

    Article first published online: 23 MAY 2012 | DOI: 10.1002/ejoc.201200179

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    The Michael addition of cyclic diketones to β,γ-unsaturated α-keto esters catalyzed by bifunctional squaramide-derived chiral catalysts to afford adducts in high yields (up to 95 %) and excellent enantioselectivities (up to 99 % ee) under mild conditions is reported. The reaction affords chiral Michael adducts, which are important moieties in the skeletons of biological and pharmaceutical molecules.

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