European Journal of Organic Chemistry

Cover image for Vol. 2014 Issue 25

Editor: Haymo Ross, Deputy Editor: Susan Wilkinson

Impact Factor: 3.154

ISI Journal Citation Reports © Ranking: 2013: 14/58 (Chemistry Organic)

Online ISSN: 1099-0690

Associated Title(s): Advanced Synthesis & Catalysis, Asian Journal of Organic Chemistry

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A Fragrance That Breaks the Rules - Synthesis of a Spirocyclic Seco Structure of the Principal Vetiver Odorant Khusimone

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A Fragrance That Breaks the Rules

Synthesis of a Spirocyclic Seco Structure of the Principal Vetiver Odorant Khusimone.
Approximately one third of all fragrances on the market contain vetiver oil as a key ingredient, for which no synthetic odorant is commercially available. Instead it has to be distilled from the dried roots of vetiver grass. To find out about the structural requirements of vetiver odorants, researchers in Switzerland devised a synthesis to a 7,8-seco-khusimone, which still contained all the structural features held responsible for the vetiver odour. As they report in the European Journal of Organic Chemistry, however, the final product displayed none of the expected olfactory characteristics, thus proving the vetiver rule wrong.

Read more.

No.Press ReleaseOriginal Communication

05/2012

A Fragrance That Breaks the Rules
Synthesis of a Spirocyclic Seco Structure of the Principal Vetiver Odorant Khusimone
(PDF)

Synthesis of a Spirocyclic Seco Structure of the Principal Vetiver Odorant Khusimone

Philip Kraft, Givaudan Schweiz AG, Dübendorf (Switzerland)


04/2012

Electrophilic Sneeze
Terpenoids isolated from common ragweed show ability to induce airways irritation
(PDF)

Sesquiterpenoids from Common Ragweed (Ambrosia artemisiifolia L.), an Invasive Biological Polluter

Giovanni Appendino, Università degli Studi del Piemonte Orientale, Novara (Italy)


03/2012

Prevent This!
Efficient Preparation of a Set of Potential Glycosidase Inhibitors
(PDF)

Synthesis of Eight 1-Deoxynojirimycin Isomers from a Single Chiral Cyanohydrin

Herman S. Overkleeft, Universiteit Leiden (The Netherlands)


02/2012

Stay Calm with Domino
Preparation of Benzodiazepine-Containing Drugs
(PDF)

Microwave-Assisted Domino Benzannulation of α-Oxo Ketenes: Preparation of 1,3-Dihydro-2H-1,5-benzodiazepin-2-ones

Yoann Coquerel, Aix-Marseille Université (France)


01/2012

Avoid the Fallout
New Ligands for Nuclear Waste Treatment
(PDF)

Synthesis and Evaluation of Lipophilic BTBP Ligands for An/Ln Separation in Nuclear Waste Treatment: The Effect of Alkyl Substitution on Extraction Properties and Implications for Ligand Design

Laurence Harwood, University of Reading (UK)


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