Biomedical Chromatography

Cover image for Vol. 31 Issue 8

Early View (Online Version of Record published before inclusion in an issue)

Editor-in-Chief: M. G. Bartlett

Impact Factor: 1.613

ISI Journal Citation Reports © Ranking: 2016: 49/76 (Chemistry Analytical); 59/77 (BIOCHEMICAL RESEARCH METHODS); 192/256 (Pharmacology & Pharmacy); 231/286 (Biochemistry & Molecular Biology)

Online ISSN: 1099-0801

VIEW

  1. 1 - 90
  1. RESEARCH ARTICLES

    1. Quantitative bioanalysis of bavachalcone in rat plasma by LC–MS/MS and its application in a pharmacokinetics study

      Dan Zhou, Lianhua An, Yan Xia, Yuanyi Wang and Xingliang Li

      Version of Record online: 20 JUL 2017 | DOI: 10.1002/bmc.4031

  2. SHORT COMMUNICATIONS

  3. RESEARCH ARTICLES

    1. Metabolomics revealed the toxicity of cationic liposomes in HepG2 cells using UHPLC-Q-TOF/MS and multivariate data analysis

      Jing Yu, Hai Zhang, Ying Li, Sen Sun, Jie Gao, Yanqiang Zhong, Duxin Sun and Guoqing Zhang

      Version of Record online: 17 JUL 2017 | DOI: 10.1002/bmc.4036

    2. Pharmacokinetic comparison of two phenolic acids after oral administration of Typhae pollen to normal rats and rats with acute cold blood stasis

      Yingni Pan, Wenjie Zhang, Wei Zhang, Xuewei Bai, Shumeng Ren, Jiang Zheng, Dongmei Wang and Xiaoqiu Liu

      Version of Record online: 16 JUL 2017 | DOI: 10.1002/bmc.4028

    3. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent

      Sipho Mdanda, Sooraj Baijnath, Adeola Shobo, Sanil D. Singh, Glenn E.M. Maguire, Hendrik G. Kruger, Per I. Arvidsson, Tricia Naicker and Thavendran Govender

      Version of Record online: 13 JUL 2017 | DOI: 10.1002/bmc.4035

  4. SPECIAL ISSUE: REVIEWS

  5. RESEARCH ARTICLES

    1. LC–MS/MS characterization, anti-inflammatory effects and antioxidant activities of polyphenols from different tissues of Korean Petasites japonicus (Meowi)

      Jin Young Choi, Kebede Taye Desta, Venu Venkatarame Gowda Saralamma, Sung Joong Lee, Soo Jung Lee, Seong Min Kim, Anjugam Paramanantham, Ho Jeong Lee, Yun-Hi Kim, Ho-Chul Shin, Jae-Han Shim, Mohamad Warda, Ahmet Hacımüftüoğlu, Ji Hoon Jeong, Sung Chul Shin, Gon-Sup Kim and A. M. Abd El-Aty

      Version of Record online: 11 JUL 2017 | DOI: 10.1002/bmc.4033

  6. SPECIAL ISSUE: REVIEWS

    1. You have free access to this content
  7. RESEARCH ARTICLES

    1. A validated UHPLC–MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples

      Suzanne L. Parker, Yarmarly C. Guerra Valero, Jeffrey Lipman, Steven Weiss, Camilla Smith, Lyndal Russell, Paul Smith, Jason A. Roberts and Steven C. Wallis

      Version of Record online: 10 JUL 2017 | DOI: 10.1002/bmc.4030

    2. Determination of the serine palmitoyl transferase inhibitor myriocin by electrospray and Q-trap mass spectrometry

      Giuseppe Matteo Campisi, Paola Signorelli, Jessica Rizzo, Claudio Ghilardi, Jacopo Antognetti, Anna Caretti, Jelena S. Lazarević, Enrica Strettoi, Elena Novelli, Riccardo Ghidoni, Federico Maria Rubino and Rita Paroni

      Version of Record online: 10 JUL 2017 | DOI: 10.1002/bmc.4026

    3. Metabolic profiling of quercetin in rats using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry

      Ming-jiang Wu, Xiao-lei Wu, De-qin Zhang, Feng Qiu, Li-qin Ding, Hao-ling Ma and Xin-ze Chen

      Version of Record online: 4 JUL 2017 | DOI: 10.1002/bmc.4016

    4. Development of a validated UPLC–MS/MS method for determination of humantenmine in rat plasma and its application in pharmacokinetics and bioavailability studies

      Yanxian Hu, Minghao Chen, Zhaoyu Wang, Yao Lan, Lan Tang, Menghua Liu, Jie Zhao, Ming Hu, Lulu Zhang and Ling Ye

      Version of Record online: 3 JUL 2017 | DOI: 10.1002/bmc.4017

  8. SHORT COMMUNICATIONS

    1. Quantification of morusin using LC–MS in rat plasma: Application to a pharmacokinetic study

      Zhipeng Deng, Xiaohui Sun, Shenbao Yang, Lei Zhang, Peilu Sun, Xuepeng Teng and Hao Zhong

      Version of Record online: 29 JUN 2017 | DOI: 10.1002/bmc.4021

  9. RESEARCH ARTICLES

    1. Relationship between the UPLC-Q-TOF-MS fingerprinted constituents from Daphne genkwa and their anti-inflammatory, anti-oxidant activities

      Wen-Juan Du, Jun Ji, Ling Wang, Xin-Yi Lan, Jia Li, Jun-Qiu Lei, Xin He, Chun-Feng Zhang, Wen-Zhe Huang, Zhen-Zhong Wang, Wei Xiao, Chong-Zhi Wang and Chun-Su Yuan

      Version of Record online: 20 JUN 2017 | DOI: 10.1002/bmc.4012

    2. Screening free radical scavengers in Xiexin Tang by HPLC-ABTS-DAD-Q-TOF/MS

      Yu-Qing Wang, Shu-Jiao Li, Guo Zhuang, Rong-Hui Geng and Xu Jiang

      Version of Record online: 20 JUN 2017 | DOI: 10.1002/bmc.4002

    3. Development and validation of HPLC-MS/MS method for the determination of lixivaptan in mouse plasma and its application in a pharmacokinetic study

      Adnan A. Kadi, Haitham Alrabiah, Mohamed W. Attwa, Sabry Attia and Gamal A. E. Mostafa

      Version of Record online: 16 JUN 2017 | DOI: 10.1002/bmc.4007

    4. Validated UHPLC–MS/MS assay for quantitative determination of etoposide, gemcitabine, vinorelbine and their metabolites in patients with lung cancer

      Xiaobin Gong, Le Yang, Feng Zhang, Youtian Liang, Shouhong Gao, Ke Liu and Wansheng Chen

      Version of Record online: 15 JUN 2017 | DOI: 10.1002/bmc.3989

    5. Suitability of selected chromatographic columns for analysis of fatty acids in dialyzed patients

      Magdalena Pazda, Piotr Stepnowski, Tomasz Sledzinski, Michal Chmielewski and Adriana Mika

      Version of Record online: 15 JUN 2017 | DOI: 10.1002/bmc.4006

    6. Comparative pharmacokinetics of acteoside from total glycoside extracted from leaves of Rehmannia and Dihuangye total glycoside capsule in normal and diabetic nephropathy rats

      Xin-Xin Dai, Shu-Lan Su, Hong-Die Cai, Dan-Dan Wei, Tian-Yao Zheng, Zhen-Hua Zhu, Hui Yan, Er-Xin Shang, Sheng Guo, Da-Wei Qian and Jin-Ao Duan

      Version of Record online: 14 JUN 2017 | DOI: 10.1002/bmc.4013

    7. Structural identification of degradants of moexipril by LC–MS/MS

      Purushotham Reddy Challa, Ramakrishna K. and Narayana Rao K. M. V.

      Version of Record online: 7 JUN 2017 | DOI: 10.1002/bmc.4004

  10. LETTERS TO THE EDITOR

  11. RESEARCH ARTICLES

    1. Development and validation of an LC-ESI-MS/MS approach to determine a highly hydrophobic drug, norcantharidin palmitate, and apply to a preliminary pharmacokinetic study in rats

      Xiaolin Liu, Xiaoguang Tao, Qi Zheng, Hang Xu, Yu Zhang, Tian Lei, Tian Yin, Haibing He and Xing Tang

      Version of Record online: 5 JUN 2017 | DOI: 10.1002/bmc.4010

    2. Identification of differential metabolic characteristics between tumor and normal tissue from colorectal cancer patients by gas chromatography–mass spectrometry

      Wu Ning, Haijing Li, Fanqiang Meng, Jianhua Cheng, Xin Song, Guochao Zhang, Wenyue Wang, Shengming Wu, Junjian Fang, Kunpeng Ma, Jie Yang, Dongpo Pei and Fangting Dong

      Version of Record online: 2 JUN 2017 | DOI: 10.1002/bmc.3999

    3. LC/QTOF profile and preliminary stability studies of an enriched flavonoid fraction of Cecropia pachystachya Trécul leaves with potential antidepressant-like activity

      Caroline Flach Ortmann, Helena Mendes Abelaira, Gislaine Zilli Réus, Zuleide Maria Ignácio, Vitor Clasen Chaves, Talitha Caldas dos Santos, Pâmela de Carvalho, Anelise Scussel Carlessi, Livia Bruchchen, Lucineia G. Danielski, Simone Gonçalves Cardoso, Angela Machado de Campos, Fabricia Petronilho, Joyce Rebelo, Meline Oliveira dos Santos Morais, Francieli Vuolo, Felipe Dal-Pizzol, Emilio Luiz Streck, João Quevedo and Flávio Henrique Reginatto

      Version of Record online: 31 MAY 2017 | DOI: 10.1002/bmc.3982

    4. An HPLC method for simultaneous quantitative determination of seven secoiridoid glucosides separated from the roots of Ilex pubescens

      Yang Zhang, Huan Xiong, Jiayi Bi, Guiyun Zhao, Yi Yang, Xue Chen, Yuncong Li, Chongyu Zhang and Guogang Zhang

      Version of Record online: 30 MAY 2017 | DOI: 10.1002/bmc.3995

    5. Sensitive and specific LC-ESI-MS/MS method for determination of ZYDPLA1, a novel long-acting dipeptidyl peptidase 4 inhibitor in rat plasma: An application for toxicokinetic study in rats

      Poonam Giri, Nirmal Patel, Bharat Patel, Harilal Patel, Rajesh Bahekar, Nuggehally R. Srinivas, Pankaj R. Patel and Ranjit Desai

      Version of Record online: 29 MAY 2017 | DOI: 10.1002/bmc.3984

    6. Analysis of toldimfos in porcine muscle and bovine milk using liquid chromatography–triple quadrupole mass spectrometry

      Dan Zhang, Jin-A Park, A. M. Abd El-Aty, Seong-Kwan Kim, Sang-Hyun Cho, Weijia Zheng, Jeong-min Choi, Jae-Han Shim, Byung-Joon Chang, Jin-Suk Kim and Ho-Chul Shin

      Version of Record online: 24 MAY 2017 | DOI: 10.1002/bmc.3996

    7. A novel mass spectrometry-based method for simultaneous determination of asymmetric and symmetric dimethylarginine, l-arginine and l-citrulline optimized for LC-MS-TOF and LC-MS/MS

      Jerzy Wiśniewski, Mariusz G. Fleszar, Joanna Piechowicz, Małgorzata Krzystek-Korpacka, Angelika Chachaj, Andrzej Szuba, Katarzyna Lorenc-Kukula, Leszek Masłowski, Wojciech Witkiewicz and Andrzej Gamian

      Version of Record online: 24 MAY 2017 | DOI: 10.1002/bmc.3994

    8. Therapeutic drug monitoring of mitotane: Analytical assay and patient follow-up

      Catherine Feliu, Yoann Cazaubon, Helene Guillemin, Damien Vautier, Olivier Oget, Hervé Millart, Claire Gozalo and Zoubir Djerada

      Version of Record online: 21 MAY 2017 | DOI: 10.1002/bmc.3993

    9. Free mycophenolic acid determination in human plasma ultrafiltrate by a validated liquid chromatography–tandem mass spectrometry method

      Paulina Łuszczyńska, Tomasz Pawiński, Paweł K. Kunicki, Katarzyna Sikorska and Ryszard Marszałek

      Version of Record online: 21 MAY 2017 | DOI: 10.1002/bmc.3976

    10. UHPLC-Q-TOF-MS/MS-based screening and characterization of metabolites of cnidilin in human liver microsomes

      Lin Yuan, Yuqian Zhang, Man Liao, Yanyan Liu, Changchen Wan and Lantong Zhang

      Version of Record online: 21 MAY 2017 | DOI: 10.1002/bmc.3992

    11. Analytical challenges in quantifying abiraterone with LC–MS/MS in human plasma

      Guillemette E. Benoist, Eric van der Meulen, Floor J.E. Lubberman, Winald R. Gerritsen, Tineke J. Smilde, Jack A. Schalken, Jan H. Beumer, David M. Burger and Nielka P. van Erp

      Version of Record online: 16 MAY 2017 | DOI: 10.1002/bmc.3986

    12. A chiral LC-MS/MS method for the enantioselective determination of R-(+)- and S-(–)-pantoprazole in human plasma and its application to a pharmacokinetic study of S-(–)-pantoprazole sodium injection

      Huiwen Jiao, Yueqi Li, Luning Sun, Hongwen Zhang, Liyuan Yu, Lei Yu, Ziqingyun Yuan, Lijun Xie, Juan Chen and Yongqing Wang

      Version of Record online: 7 MAY 2017 | DOI: 10.1002/bmc.3980

    13. The effect of tripterygium glucoside tablet on pharmacokinetics of losartan and its metabolite EXP3174 in rats

      Yongsheng Hu, Xuexue Zhou, Hui Shi, Wenyu Shi, Shengjie Ye and Hai Zhang

      Version of Record online: 24 APR 2017 | DOI: 10.1002/bmc.3973

    14. Simultaneous determination of piperaquine and its N-oxidated metabolite in rat plasma using LC-MS/MS

      Huixiang Liu, Meitong Zang, Aijuan Yang, Jianbo Ji and Jie Xing

      Version of Record online: 19 APR 2017 | DOI: 10.1002/bmc.3974

    15. Simultaneous determination of wogonin, oroxylin a, schisandrin, paeoniflorin and emodin in rat serum by HPLC–MS/MS and application to pharmacokinetic studies

      Minting Chen, Suying Wei, Chaohua Luo, Feilong Chen, Shuai Song, Qun Shen, Zhixian Mo and Fenghuan Wei

      Version of Record online: 19 APR 2017 | DOI: 10.1002/bmc.3966

    16. A novel assay to determine acetylcholinesterase activity: The application potential for screening of drugs against Alzheimer's disease

      Liang Peng, Zhengxing Rong, Hao Wang, Biyun Shao, Lei Kang, Hong Qi and Hongzhuan Chen

      Version of Record online: 18 APR 2017 | DOI: 10.1002/bmc.3971

    17. Comparison of 6-mercaptopurine with 6-thioguanine for the analysis of thiopurine S-methyltransferase activity in human erythrocyte by LC–MS/MS

      Shenghui Mei, Xindi Li, Xiaoqing Gong, Xiaoyi Zhang, Xingang Li, Li Yang, Leting Zhu, Heng Zhou, Yonghong Liu, Anna Zhou, Xinghu Zhang and Zhigang Zhao

      Version of Record online: 29 MAR 2017 | DOI: 10.1002/bmc.3959

    18. Long-chain unsaturated fatty acids as possible important metabolites for primary angle-closure glaucoma based on targeted metabolomic analysis

      Shengzhong Rong, Yang Li, Yue Guan, Lili Zhu, Qiang Zhou, Mucong Gao, Hongzhi Pan, Lina Zou and Dong Chang

      Version of Record online: 26 MAR 2017 | DOI: 10.1002/bmc.3963

    19. Stability studies of potent opioid analgesic, morphine-6-O-sulfate in various buffers and biological matrices by HPLC-DAD analysis

      Jai Shankar K. Yadlapalli, Zaineb A.F. Albayati, Narasimha R. Penthala, Howard P. Hendrickson and Peter A. Crooks

      Version of Record online: 24 MAR 2017 | DOI: 10.1002/bmc.3957

    20. Chemical composition differentiation of Shen-Shuai-Ning granule between combined decoction and separated decoction using HPLC-DAD-ESI-QTOF-MS

      Jianli Liu, Yu Zhang, Yimeng Hao, Ying Zhao, Yanjiao Li, Rulan Qin, Chongning Lv and Jincai Lu

      Version of Record online: 23 MAR 2017 | DOI: 10.1002/bmc.3949

    21. Dissipation kinetics and pre-harvest residue limit of pyriofenone in oriental melon (Cucumis melo Var. makuwa) grown under regulated climatic conditions

      Hyung Suk Chung, Md. Humayun Kabir, A.M. Abd El-Aty, Han Sol Lee, Md. Musfiqur Rahman, Byung-Joon Chang, Ho-Chul Shin and Jae-Han Shim

      Version of Record online: 21 MAR 2017 | DOI: 10.1002/bmc.3965

    22. Effect of alprazolam on rat serum metabolic profiles

      Yan Li, Gaotong Lin, Bingbao Chen, Jing Zhang, Lingtian Wang, Zixia Li, Yungang Cao, Congcong Wen, Xuezhi Yang, Gaozhong Cao, Xianqin Wang and Guoquan Cao

      Version of Record online: 16 MAR 2017 | DOI: 10.1002/bmc.3956

    23. Simultaneous quantification of antofloxacin and its major metabolite in human urine by HPLC–MS/MS, and its application to a pharmacokinetic study

      Yunsu Ma, Qianru Wang, Hongwen Zhang, Lijun Xie, Juan Chen, Mao Huang, Yun Liu, Yuanyuan Wang, Libin Wang, Luning Sun and Ning Ou

      Version of Record online: 15 MAR 2017 | DOI: 10.1002/bmc.3962

    24. Development and validation of a high-throughput online solid-phase extraction–liquid chromatography–tandem mass spectrometry method for the detection of gonyautoxins 1&4 and gonyautoxins 2&3 in human urine

      Rebecca Coleman, Sharon W. Lemire, William Bragg, Alaine Garrett, Geovannie Ojeda-Torres, Rebekah Wharton, Elizabeth Hamelin, Jerry Thomas and Rudolph C. Johnson

      Version of Record online: 14 MAR 2017 | DOI: 10.1002/bmc.3954

    25. Development and validation of a reversed-phase HPLC method for licarbazepine monitoring in serum of patients under oxcarbazepine treatment

      Elias Begas, Andreas Tsakalof, Efthimios Dardiotis, Georgios Emmanouil Vatidis, Evangelos Kouvaras and Eftihia Konstadinos Asprodini

      Version of Record online: 10 MAR 2017 | DOI: 10.1002/bmc.3950

    26. Chromatographic determination of harmalans in the urine of autistic children

      Joanna Kałużna-Czaplińska, Jagoda Jóźwik-Pruska and Andrea Axt

      Version of Record online: 9 MAR 2017 | DOI: 10.1002/bmc.3951

    27. Simultaneous determination of eight B-vitamins in rat intestinal perfusate to identify effects of osmotic pressures on absorptions

      Xiaobo Wang, Jian Xiao, Hui Zhou, Ying Qiu, Hui Peng, Yangyang Sun, Jiwen Zhang, Wei Qian and Lixin Sun

      Version of Record online: 7 MAR 2017 | DOI: 10.1002/bmc.3952

    28. The establishment of tocopherol reference intervals for Hungarian adult population using a validated HPLC method

      Gábor Veres, László Szpisjak, Attila Bajtai, Andrea Siska, Péter Klivényi, István Ilisz, Imre Földesi, László Vécsei and Dénes Zádori

      Version of Record online: 7 MAR 2017 | DOI: 10.1002/bmc.3953

  12. REVIEWS

    1. Application of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4D): An update

      Abdalla A. Elbashir, Oliver J. Schmitz and Hassan Y. Aboul-Enein

      Version of Record online: 27 FEB 2017 | DOI: 10.1002/bmc.3945

  13. RESEARCH ARTICLES

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