Biopharmaceutics & Drug Disposition

Cover image for Vol. 38 Issue 8

Edited By: K. Sandy Pang

Impact Factor: 2.091

ISI Journal Citation Reports © Ranking: 2016: 157/257 (Pharmacology & Pharmacy)

Online ISSN: 1099-081X

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Special Issue: Role of Gut Wall in the Fate of Orally Administered Drugs
Part 1Part 2

These special issues contain a series of articles that bring together original research as well as critical reviews on gut wall drug metabolism and absorption, with emphasis on topics of gut wall attributes and their importance in considering the fate of orally administered drugs.

Free Review articles
Projecting human pharmacokinetics of monoclonal antibodies from nonclinical data: comparative evaluation of prediction approaches in early drug development
Jing Wang, Suhasini Iyer, et al.

Challenges and advances in the assessment of the disposition of antibody-drug conjugates
Amrita V. Kamath and Suhasini Iyer

Plasma vs heart tissue concentration in humans – literature data analysis of drugs distribution
Zofia Tylutki and Sebastian Polak

Dealing with the complex drug–drug interactions: Towards mechanistic models
Manthena V. Varma, K. Sandy Pang,et al.

Recently Published Articles

  1. Hepatocellular uptake of cyclodextrin-complexed curcumin during liver preservation: A feasibility study

    Saber Abdelkader Saidi, Nicolas Meurisse, Ina Jochmans, Veerle Heedfeld, Tine Wylin, Jaakko Parkkinen, Jacques Pirenne, Diethard Monbaliu, Abdelfattah El Feki and Jos van Pelt

    Version of Record online: 20 NOV 2017 | DOI: 10.1002/bdd.2108

  2. Multiple organic cation transporters contribute to the renal transport of sulpiride

    Liping Li, Yayun Weng, Wei Wang, Mengru Bai, Hongmei Lei, Hui Zhou and Huidi Jiang

    Version of Record online: 20 NOV 2017 | DOI: 10.1002/bdd.2104

  3. Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies

    Norie Murayama, Kanako Yajima, Mikiko Hikawa, Kanami Shimura, Yu Ishii, Masaki Takada, Yasuhiro Uno, Masahiro Utoh, Kazuhide Iwasaki and Hiroshi Yamazaki

    Accepted manuscript online: 14 NOV 2017 05:45PM EST | DOI: 10.1002/bdd.2115