Cell Biochemistry and Function

Cover image for Vol. 33 Issue 4

Edited By: Nigel Loveridge

Impact Factor: 2.005

ISI Journal Citation Reports © Ranking: 2014: 143/184 (Cell Biology); 205/289 (Biochemistry & Molecular Biology)

Online ISSN: 1099-0844

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  1. Hsa-miR-132 inhibits proliferation of hepatic carcinoma cells by targeting YAP

    Chang-Jiang Lei, Lei Li, Xia Gao, Jun Zhang, Qing-Yun Pan, Hao-Cheng Long, Chun-Zhou Chen, De-Fa Ren and Gang Zheng

    Article first published online: 19 JUN 2015 | DOI: 10.1002/cbf.3119

  2. You have full text access to this OnlineOpen article
    An ex vivo model using human osteoarthritic cartilage demonstrates the release of bioactive insulin-like growth factor-1 from a collagen–glycosaminoglycan scaffold

    J. Wardale, L. Mullen, D. Howard, S. Ghose and N. Rushton

    Article first published online: 9 JUN 2015 | DOI: 10.1002/cbf.3112


    Pre-clinical trials of biomaterials for cartilage repair are very costly, and all too often, studies progress directly from in vitro studies using isolated cells to in vivo studies without investigating the interaction between the target tissue and the scaffold. Our study uses viable cartilage from adult human donors with osteoarthritis and therefore represents the exact scenario that the scaffold is designed for. The system is cheap and simple to set up and is suitable for a 48-well plate format, meaning a reasonable throughput is obtainable. This lends the model to therapeutic drug testing.

  3. Comparison of the effect of raw and blanched-frozen broccoli on DNA damage in colonocytes

    Anthony Lynn, Zoë Fuller, Andrew R. Collins and Brian Ratcliffe

    Article first published online: 9 JUN 2015 | DOI: 10.1002/cbf.3106