Cell Biochemistry and Function

Cover image for Vol. 34 Issue 3

Edited By: Nigel Loveridge

Impact Factor: 2.005

ISI Journal Citation Reports © Ranking: 2014: 143/184 (Cell Biology); 205/290 (Biochemistry & Molecular Biology)

Online ISSN: 1099-0844

Author Guidelines

NIH Public Access Mandate
For those interested in Wiley policy on the NIH Public Access Mandate, please visit our policy statement

For additional tools visit Author Resources - an enhanced suite of online tools for Wiley Online Library journal authors, featuring Article Tracking, E-mail Publication Alerts and Customized Research Tools.

Author Guidelines

Cell Biochemistry and Function is an online journal that publishes original research articles and reviews on the mechanisms whereby molecular and biochemical processes control cellular activity. This should have a particular emphasis on the integration of molecular and cell biology, biochemistry and physiology in the regulation of tissue function in health and disease.

The primary remit of the journal is on mammalian biology both in vivo and in vitro, but studies of cells in situ are especially encouraged. Observational and pathological studies will be considered providing they include a rational discussion of the possible molecular and biochemical mechanisms behind them and the immediate impact of these observations to our understanding of mammalian biology.

Areas of particular interest include:

  • Dysregulation of cellular function in disease
  • Cell cycle control with respect to cell proliferation, differentiation and death
  • DNA and RNA processing and the effects on cellular activity
  • The regulation of stem cells and regenerative medicine
  • Intra-cellular organelles, metabolism and the control of cell function
  • Local niches and cell function.

Types of contribution. The editors welcome original research papers, rapid communications, commentaries and letters. Reviews are usually commissioned but unsolicited, high quality reviews on the integration of cellular function and suggestions for future topics will also be welcomed after discussion with the review editor. There are no restrictions on length but papers may be subject to editorial amendment if accepted.

Submissions will be placed in one of the following sections

  • Cell Cycle/Nucleic Acids/Protein Synthesis
  • Cardiovascular Science
  • Cell Signalling
  • Connective Tissues
  • Endocrinology and Cell Metabolism
  • Infection and Immunity
  • Neuroscience
  • Nutrition/Toxicology/Free Radical

Refereeing. All manuscripts are subject to a confidential reviewing process. Referees' comments will be made available to authors to ensure openness of the review process.


Cell Biochemistry and Function operates an online submission and peer review system that allows authors to submit articles online and track their progress via a web interface. Please read the remainder of these instructions to authors and then visit http://mc.manuscriptcentral.com/cbf and navigate to the Cell Biochemistry and Function online submission site.

IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created.

All papers must be submitted via the online system.

Required information

Failure to supply the following information may result in immediate rejection.

1) Manuscripts must be accompanied by a Submission Letter confirming that all authors have agreed to the submission and that it has not been submitted elsewhere.

2) Authors are required to upload a paragraph detailing the significance of their paper in the context of current knowledge. This will be published as part of the final manuscript.

3) Authors are required to supply with every submitted manuscript the names and contact details of 4 possible reviewers. These should NOT be members of the Editorial Board with at least 2 currently working outside the country from which the paper is submitted. Authors should indicate which Editorial Board member is most appropriate for reviewing the submission, although the Editor-in-Chief may choose another for reasons of speed.

File types. Preferred formats for the text and tables of your manuscript are .doc, .docx, .rtf, .ppt, .xls. LaTeX files may be submitted provided that an .eps or .pdf file is provided in addition to the source files. Figures may be provided in .tiff or .eps format.


Non-LaTeX users. Upload your manuscript files. At this stage, further source files do not need to be uploaded.
LaTeX users. For reviewing purposes you should upload a single .pdf that you have generated from your source files. You must use the File Designation "Main Document" from the dropdown box.


Non-LaTeX users. Editable source files must be uploaded at this stage. Tables must be on separate pages after the reference list, and not be incorporated into the main text. Figures should be uploaded as separate figure files.
LaTeX users. When submitting your revision you must still upload a single .pdf that you have generated from your revised source files. You must use the File Designation "Main Document" from the dropdown box. In addition you must upload your TeX source files. For all your source files you must use the File Designation "Supplemental Material not for review". Previous versions of uploaded documents must be deleted. If your manuscript is accepted for publication we will use the files you upload to typeset your article within a totally digital workflow.

Electronic Enhancement/Supporting Information. Data that are (i) not amenable to presentation in a traditional print format, (ii) of interest primarily to specialists and do not require Journal page space, or (iii) particularly useful to the community in electronic (downloadable) form can be published online as supporting information hosted within Wiley Online Library.


OnlineOpen is available to authors of articles who wish to make their article open access. With OnlineOpen the author, their funding agency, or institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in PubMed Central and PMC mirror sites. In addition to publication online via Wiley Online Library, authors of OnlineOpen articles are permitted to post the final, published PDF of their article on a website, institutional repository, or other free public server, immediately on publication.

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.


If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions http://authorservices.wiley.com/bauthor/faqs_copyright.asp.

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

  • Creative Commons Attribution License OAA
  • Creative Commons Attribution Non-Commercial License OAA
  • Creative Commons Attribution Non-Commercial -NoDerivs OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQshosted on Wiley Author Services and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.

Note to NIH Grantees Pursuant to NIH mandate, Wiley Blackwell will post the accepted version of contributions authored by NIH grant holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information see http://www.wiley.com/go/funderstatement.

COPE Membership

Cell Biochemistry and Function endorses the COPE (Committee on Publication Ethics) guidelines and will pursue cases of suspected research and publication misconduct (e.g. falsification, fabrication, plagiarism, inappropriate image manipulation, redundant publication). In such cases, the journal will follow the processes set out by COPE. For more information about COPE, please visit the COPE website at http://www.publicationethics.org.uk.

Submission of a manuscript will be held to imply that it contains original unpublished work and is not being submitted for publication elsewhere at the same time. Submitted material will not be returned to the author.


The language of the journal is English. 12-point type in one of the standard fonts: Times, Helvetica, or Courier is preferred. It is not necessary to double-line space your manuscript. Tables must be on separate pages after the reference list, and not be incorporated into the main text. Figures should be uploaded as separate figure files.

  • During the submission process you must enter the full title, short title of up to 70 characters and names and affiliations of all authors. Give the full address, including email, telephone and fax, of the corresponding author who will check the proofs.
  • Include the name(s) of any sponsor(s) of the research contained in the paper, along with grant number(s).
  • Enter an abstract of up to 200 words for all articles [except book reviews]. An abstract is a concise summary of the whole paper, not just the conclusions, and is understandable without reference to the rest of the paper. It should contain no citation to other published work.
  • Include a Significance paragraph consists of a single paragraph of no more than 100 words. The main goal of the Significance paragraph is to explain the significance of the findings and their relevance in the context of cellular biochemistry and function to a broad readership, from basic to clinical research scientists. No references should be included. Please note that a paragraph on significance is not required for review articles.
  • Include at least four and up to eight keywords that describe your paper for indexing purposes.
  • The remainder should be presented as: text - including suppliers of materials and an introduction which does not recapitulate the results and conclusions; acknowledgements; references; tables; figure captions (these last three supplied separately) and illustrations.
  • Rapid communications should be less than 4 printed pages (approximately 1000 words excluding references) and contain only a single figure. They should have the same style as for full research articles.
  • Units, abbreviations and nomenclature. In general, the IUPAC-IUB commissions convention, e.g. as used by the Biochemical Journal will be followed. It is preferable to use SI units, but other, more generally used units can be used, preferably with the equivalent values in SI units in parentheses.
Reference style. References should be listed at the end of the manuscript in alphabetical order according to the name of the first author and chronologically where several papers by the same author are listed. References should be cited by superior numbers. All references must be complete and accurate. Use Medline abbreviations for journal names. They can be found at: http://www.ncbi.nlm.nih.gov/entrez/jrbrowser.cgi. Online citations should include date of access. If necessary, cite unpublished or personal work in the text but do not include it in the reference list. Where possible the DOI* for the reference should be included at the end of the reference. References should be listed in the following style:
1. Nanni G, Canepa C, Casu A. Dolichol and vitamin A content in rat liver Ito (perisinusoidal) cells. Life Sci 1997; 60 : 21-28. DOI: 10.1002/ls.258
2. Chayen J, Bitensky L. Cell Biology in Medicine; John Wiley: New York, 1973; 595-678.
3. Flohe L, Gunzler WA. 1984. Assays of glutathione peroxidase. In Methods in Enzymology, Colowick SP, Kaplan ON (eds.); Series 6; Academic Press: San Diego; 114-121.
4. The Oncology Website: http://www.mit.com/oncology/ [24 April 1999] (the data in square brackets after the website reference is an access date provided by the author).

*The Digital Object Identifier (DOI) is an identification system for intellectual property in the digital environment. Developed by the International DOI Foundation on behalf of the publishing industry, its goals are to provide a framework for managing intellectual content, link customers with publishers, facilitate electronic commerce, and enable automated copyright management.

Illustrations. Upload each figure as a separate file in either .tiff or .eps format, the figure number and the top of the figure indicated. Compound figures e.g. 1a, b, c should be uploaded as one figure. Tints are not acceptable. Lettering must be of a reasonable size that would still be clearly legible upon reduction, and consistent within each figure and set of figures. The artwork must be sized to the text width of 75 mm one column, 156 mm two column. Where a key to symbols is required, please include this in the artwork itself, not in the figure legend. All illustrations must be supplied at the correct resolution:

  • Black and white and colour photos - 300 dpi
  • Graphs, drawings etc - 800 dpi preferred; 600 dpi minimum
  • Combinations of photos and drawings (black and white and colour) - 500 dpi
  • Tables should be part of the main document and should be placed after the references. If the table is created in Excel, the file should be uploaded separately.

Colour illustrations supplied electronically in either .tiff or .eps format will be used in the online and .pdf versions of the article at no cost to the author or which will appear on the Wiley Online Library site.


Further information. For accepted manuscripts the publisher will supply proofs to the corresponding author prior to publication. This stage is to be used only to correct errors that may have been introduced during the production process. Prompt return of the corrected proofs, preferably within two days of receipt, will minimize the risk of the paper being held over to a later issue. Free access to the final PDF offprint of your article will be available via author services only (unless otherwise stated). Please sign up for author services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers. Reprints of your article and copies of the journal may be ordered. There is no page charge to authors.

Contact Information

Should the need arise, the Editor-in-Chief can be contacted as follows: Dr Nigel Loveridge, Orthopaedic Research, University of Cambridge Clinical School, Addenbrookes Hospital (Box 180), Cambridge CB2 2QQ, UK. Tel. +44 (0) 1223 748733; Fax: +44 (0) 1223 214094; e-mail: nl10003@cam.ac.uk

Author Resources. Manuscript now accepted for publication?

If so, visit our suite of tools and services for authors and sign up for:

  • Article Tracking
  • E-mail Publication Alerts
  • Personalization Tools

Cite EarlyView articles. To link to an article from the author’s homepage, take the DOI (digital object identifier) and append it to "http://dx.doi.org/" as per following example:
DOI 10.1002/hep.20941, becomes http://dx.doi.org/10.1002/hep.20941.

Publishing and the Ecology of European Research (PEER)

This journal is participating in the PEER Project, an EU-funded initiative to examine the impact on scholarly journals of depositing accepted manuscripts in web-based repositories. If the corresponding author is based in an EU country, we will deposit the accepted manuscript into the central project repository (DRIVER). The article's availability will be subject to a post-publication embargo. This project has no effect on your rights or obligations under the terms of the copyright agreement pertaining to this journal.

Pre-Submission English Language Editing. Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at http://authorservices.wiley.com/bauthor/english_language.asp Japanese authors can also find a list of local English improvement services at http://www.wiley.com.jp/journals/editcontribute.html All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Conflict of Interest. All authors must declare financial/commercial conflicts of interest. Even if there is none, this should be stated in a separate paragraph following on from the Acknowledgements section. This is a mandatory requirement for all articles.