Human Psychopharmacology: Clinical and Experimental

Cover image for Vol. 31 Issue 3

Edited By: Professor David Baldwin, Southampton, UK

Impact Factor: 2.192

ISI Journal Citation Reports © Ranking: 2014: 33/76 (Psychology); 72/140 (Psychiatry); 107/192 (Clinical Neurology); 135/255 (Pharmacology & Pharmacy)

Online ISSN: 1099-1077

Author Guidelines


Human Psychopharmacology: Clinical and Experimental (HUP) provides a forum for the evaluation of clinical and experimental research on both new and established psychotropic medicines. Experimental studies of other centrally active drugs, including herbal products, in clinical, social and psychological contexts, as well as clinical/scientific papers on drugs of abuse and drug dependency will also be considered. While the primary purpose of the Journal is to publish the results of clinical research, the results of animal studies relevant to human psychopharmacology are welcome. The following topics are of especial interest to the editors and readers of the Journal:

• All aspects of clinical psychopharmacology
• Efficacy and safety studies of novel and standard psychotropic drugs
• Studies of the adverse effects of psychotropic drugs
• Effects of psychotropic drugs on normal physiological processes
• Geriatric and paediatric psychopharmacology
• Ethical and psychosocial aspects of drug use and misuse
• Psychopharmacological aspects of sleep and chronobiology
• Neuroimaging and psychoactive drugs
• Phytopharmacology and psychoactive substances
• Drug treatment of neurological disorders
• Mechanisms of action of psychotropic drugs
• Ethnopsychopharmacology
• Pharmacogenetic aspects of mental illness and drug response
• Psychometrics: psychopharmacological methods and experimental design


HUP has adopted the following ethical guidelines for publication and research.

2.1 Original Publication

Submission of a manuscript will be held to imply that it contains original unpublished work and is not being submitted for publication elsewhere at the same time. The author must supply a full statement to the Editor-in-Chief about all submissions and previous reports that might be regarded as redundant or duplicate publication of the same or very similar work.

2.2 Authorship and Acknowledgements

Authorship: Authors submitting a paper do so on the understanding that the manuscript has been read and approved by all authors and that all authors agree to the submission of the manuscript to the Journal.

HUP adheres to the definition of authorship set up by The International Committee of Medical Journal Editors (ICMJE). According to the ICMJE authorship criteria, all named authors should meet the following conditions: 1) substantial contributions to conception and design of, or acquisition of data or analysis and interpretation of data, 2) drafting the article or revising it critically for important intellectual content and 3) final approval of the version to be published. Participation solely in the acquisition of funding or the collection of data does not justify authorship. All people who fulfil the criteria for authorship should be listed as authors.

The Editors recognise that complex, large-scale and multi-centre research will often result in a significant number of people fulfilling the authorship criteria. However, they reserve the right to ask the lead author to justify the inclusion of more than six authors.

Acknowledgements: Authors can declare grant funding, additional assistance from individuals or bodies, or any other aspect where it is felt that those individuals or bodies should be given credit. Do not mention conflicts of interest in the Acknowledgements.

2.3 Conflict of Interest and Source of Funding
HUP requires that sources of financial support for the work reported within the manuscript are fully acknowledged, and any potential conflicts of interest noted.

Conflict of Interest:
All manuscripts submitted to the Journal require a statement about authors' conflicts of interest. Please disclose any possible conflict of interest under the heading 'Conflicts of Interest' on the title page of your manuscript. Any reported conflicts of interest will be published in a highlighted box as part of the article. If no conflicts of interest are reported, the box will include the statement "No conflicts of interest have been declared". Possible conflicts of interest include financial interests relating to issues discussed in the manuscript (e.g. patent ownership, stock ownership, consultancies and speaker’s fees).

Source of Funding:
Authors are required to specify the sources of funding for their research when submitting a manuscript. These include the individuals and organisations that supplied resources for interventions as well as those that funded researcher time and other research costs. All sources of funding should be named and their location (town, state/county, country) included. The information should be provided on the title page of the manuscript and will be disclosed in the published article.

2.4 Patient Consent
When reporting experiments on human subjects, indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, as revised in 1983. Do not use patients' names, initials or hospital numbers, especially in illustrative material. When reporting experiments on animals, indicate whether the institution's or a national research council's guide for, or any national law on, the care and use of laboratory animals was followed. A statement describing explicitly the ethical background to the studies being reported should be included in all manuscripts in the Materials and Methods section. Ethics committee or institutional review board approval should be stated.

Patients have a right to privacy that should not be infringed without informed consent. Identifying information should not be published in written descriptions, photographs and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian) gives written informed consent for publication. Informed consent for this purpose requires that the patient be shown the manuscript to be published. Identifying details should be omitted if they are not essential but patient data should never be altered or falsified in an attempt to attain anonymity. Complete anonymity is difficult to achieve and informed consent should be obtained if there is any doubt. For example, masking the eye region in photographs of patients is inadequate protection of anonymity.

2.5 Appeal of Editorial Decisions
The Editors make careful judgements about the selection of manuscripts for publication, taking into account the extent to which the manuscript is consistent with the aims and scope of the Journal and their own and referees' assessments of the quality of the work and the contribution it is likely to make to knowledge, policy and practice. We are able to accept only a proportion of the manuscripts that are submitted to the Journal, and recognise that authors are often disappointed when we decline to publish their manuscripts. We strongly discourage routine appeals against such decisions. Authors who believe there were serious flaws in our editorial judgement may appeal decisions by e-mailing the editorial office with a detailed explanation of their concerns.

2.5 Permissions
If all or parts of previously published illustrations are used, permission must be obtained from the copyright holder concerned. It is the author's responsibility to obtain these permissions in writing and provide copies to the Publishers.

2.6 Copyright Assignment
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below: CTA Terms and Conditions

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following
Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

For RCUK and Wellcome Trust authors click on the link below to preview the terms and conditions of this license: Creative Commons Attribution License OAA.

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

All submissions should be made online at the Human Psychopharmacology ScholarOne Manuscripts site (formerly known as Manuscript Central)— . New users should first create an account. Once a user is logged onto the site, submissions should be made via the Author Centre.

Papers do not attract page charges. OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee (currently $3000) to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see

Prior to acceptance you should not inform the Editorial Office that you intend to publish your paper OnlineOpen. All OnlineOpen articles are treated in the same way as any other article. They go through the Journal's standard peer-review process and will be accepted or rejected based on their own merit.  

HUP invites the following types of submission. All submissions are subject to peer review:

Research Articles
Research Articles are the Journal’s primary mode of scientific communication.

Review Articles
Authors who wish to submit an unsolicited review should first contact the Editor-in-Chief to determine its suitability for publication in the Journal.

Short Communications
Short research pieces and practical inferences from clinical observations will be considered, but should not exceed 1500 words.

Case Reports
The journal does not accept case reports for publication. Authors of case reports are encouraged to submit to the Wiley Open Access journal, Clinical Case Reports which aims to directly improve health outcomes by identifying and disseminating examples of best clinical practice.


5.1 Format
Language: The language of publication is English. Authors for whom English is a second language should have their manuscript professionally edited by an English speaking person before submission to make sure the English is of high quality. You may wish to consider using our editing services which are described at All services are paid for and arranged by the author, and use of this or a similar service does not guarantee acceptance or preference for publication.

Units and Spellings: Système International (SI) units should be used, as given in Units, Symbols and Abbreviations (4th edition, 1988), published by the Royal Society of Medicine Services Ltd, 1 Wimpole Street, London W1M 8AE, UK. Other abbreviations should be used sparingly and only if a lengthy name or expression is repeated throughout the text. Spelling should conform to that used in The Concise Oxford Dictionary, published by Oxford University Press. Authors should strenuously avoid the use of jargon or obscure technical terms.

The typescript should be on A4 paper on one side only, double spaced with a wide margin on each side. The title and short title (to be printed at the head of alternate pages), authors' names, qualifications and the department(s) where the work was carried out, and the name and full postal address of the author to whom all correspondence should be sent, should be typed on a separate sheet. Please include a telephone, a fax number and an e-mail address.

Manuscripts must comply with the word limits defined in section 4. The following sections must be included, as specified in these guidelines. If these stipulations are not adhered to, your manuscript may be returned to you for resubmission, before we will consider sending it for peer review.

Title Page: The first page of the manuscript should contain the following information:
• the title of the paper
• a running head not exceeding 50 characters
• 2–6 article keywords for indexing purposes
• names of authors
• names of the institutions at which the research was conducted
• name, address, telephone and fax number, and email address of corresponding author
• the name(s) of any sponsor(s) of the research contained in the paper, along with grant number(s)

Structured Abstracts: Authors submitting Research and Review Articles should note that structured abstracts (maximum 200 words) are required. The abstract must be structured in the following format (with these subheadings): Objective, Methods, Results, Conclusions. (Authors of Reviews may use Design instead of Method.) Abstracts should contain no citation to other published work.

Text: This should in general, but not necessarily, be divided into sections with the headings: Introduction, Methods, Results, Discussion, Conclusion.

5.2 References
References should be in 'Harvard' format, with full references listed at the end of the paper, in alphabetical order by first author, as follows:

Taylor D, Paton C, Kerwin R. 2003. The Maudsley Prescribing Guidelines . Martin Dunitz: London.

Rabbitt PMA. 1982. How do old people know what to do next? In Aging and Cognitive Processes , Craik FIM, Trehub S (eds). Plenum Press: New York; 79-98.

Baune BT, Caliskan S, Todder T. 2007. Effects of adjunctive antidepressant therapy with quetiapine on clinical outcome, quality of sleep and daytime motor activity in patients with treatment-resistant depression. Hum Psychopharmacol 22 : 1–9.

(Titles of periodicals should be abbreviated according to the style used in Index Medicus.)

The Editor and Publisher recommend that citation of online published papers and other material should be done via a DOI (digital object identifier), which all reputable online published material should have — see for more information. If an author cites anything which does not have a DOI they run the risk of the cited material not being traceable.

5.3 Figures and Tables
Figures: All graphs, drawings and photographs are considered figures and should be numbered in Arabic numerals e.g. Fig. 1, Fig. 2, etc. in order of appearance. Each figure should have a legend and all legends should be typed together on a separate sheet and numbered correspondingly. If all or parts of previously published illustrations are used, permission must be obtained from the copyright holder concerned. It is the author's responsibility to obtain these in writing and provide copies to the Publisher.

In the full-text online edition of the Journal figure legends may be truncated in abbreviated links to the full screen version. Therefore the first 100 characters of any legend should inform the reader of key aspects of the figure.

Tables: Clear tables presenting relevant data are welcome. If tables of important data are particularly lengthy (e.g. tables reporting details of a large number of studies included in a systematic review), the Editors may suggest that some are published as supporting online material. Each table must be typewritten on a separate sheet and should be numbered consecutively with Arabic numerals, e.g. Table 1, and given a short caption. No vertical rules should be used. Units should appear in parentheses in the column headings and not in the body of the table. All abbreviations should be defined in a footnote.

Electronic Artwork: We would like to receive your artwork in electronic form. Please save vector graphics (e.g. line artwork) in Encapsulated Postscript format (EPS), and bitmap files (e.g. half-tones) in Tagged Image File Format (TIFF). Ideally, vector graphics that have been saved in metafile (.WMF) or pict (.PCT) format should be embedded within the body of the text file.

Further information can be obtained at Wiley Blackwell's guidelines for figures:

5.4 Colour Artwork
It is the policy of the HUP for authors to pay the full cost for the reproduction of their colour artwork. Therefore, please note that if there is colour artwork in your manuscript when it is accepted for publication, Wiley Blackwell require you to complete and return a Colour Work Agreement form before your paper can be published.

Any article received by Wiley Blackwell with colour work will not be published until the form has been returned. If you are unable to access the Internet, or are unable to download the form, please contact the Production Editor for a form. In compliance with the Payment Card Industry Data Security Standard, the Colour Work Agreement Form should be sent by post or courier to the address below, should you require colour:

Customer Services (OPI)
John Wiley & Sons Ltd
European Distribution Centre
New Era Estate
Oldlands Way
Bognor Regis
West Sussex PO22 9NQ8

5.5 Supporting Information
Supporting Information can be a useful way for an author to include important but ancillary information with the online version of an article. Examples of Supporting Information include additional tables, data sets, figures, movie files, audio clips, 3D structures, and other related nonessential multimedia files. Supporting Information should be cited within the article text, and a descriptive legend should be included. It is published as supplied by the author, and a proof is not made available prior to publication; for these reasons, authors should provide any Supporting Information in the desired final format.

For further information on recommended file types and requirements for submission, please visit:

6. After Acceptance
Upon acceptance of a paper for publication, the manuscript will be forwarded to the Production Editor who is responsible for the production of the Journal.

Online Production Tracking: Online production tracking is available for your article through Wiley Blackwell's Author Services. Author Services enables authors to track their article — once it has been accepted — through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production. Authors will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

Proof Corrections: The corresponding author will receive an e-mail alert containing a link to a website. A working e-mail address must therefore be provided for the corresponding author. The proof can be downloaded as a PDF (portable document format) file from this site. Acrobat Reader will be required in order to read this file. This software can be downloaded (free of charge) from the following website: This will enable the file to be opened, read on screen, and printed out in order for any corrections to be added. Further instructions will be sent with the proof. Hard copy proofs will be posted if no e-mail address is available; in your absence, arrange for a colleague to access your e-mail to retrieve the proofs.

Early View Publication: HUP is covered by Wiley Blackwell’s Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so these articles cannot be cited in the traditional way. They are given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before it is allocated to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article.

Search Engine Optimization for Your Paper: By optimizing your article for search engines, you will increase the chance of someone finding it. This in turn will make it more likely to be viewed and/or cited in another work. Consult our SEO Tips for Authors page in order to maximize online discoverability for your published research. Included are tips for making your title and abstract SEO-friendly, choosing appropriate keywords, and promoting your research through social media.

Offprints: Free access to the final PDF offprint of your article will be available via Author Services only. Please therefore sign up for Author Services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers. Additional paper offprints may be ordered online. Please click on this link, fill in the necessary details and ensure that you type information in all of the required fields.

If you have queries about offprints, please email

Note to NIH Grantees: Pursuant to NIH mandate, Wiley Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information, see

Author Material Archive Policy: Please note that unless specifically requested, Wiley Blackwell will dispose of all hardcopy or electronic material submitted two months after publication. If you require the return of any material submitted, please inform the Editorial Office or Production Editor as soon as possible if you have not yet done so.