© John Wiley & Sons Ltd
Editor-in-Chief: Satyajit D. Sarker
Impact Factor: 2.497
ISI Journal Citation Reports © Ranking: 2015: 25/75 (Chemistry Analytical); 37/77 (BIOCHEMICAL RESEARCH METHODS); 49/209 (Plant Sciences)
Online ISSN: 1099-1565
Many Congratulations to Award Winners
Congratulations to Andy J. Pérez, Institute of Soil Science and Plant Cultivation, State Research Institute, Poland and Jan Šimura, Palacký University of Olomouc, Czech Republic on winning the PCA best oral presentation awards at the 2016 Trends in Natural Products Research conference, and to Yaroslav Faletrov, Belarusian State University, Belarus on winning the PCA best oral presentation award at the 23rd Conference on Isoprenoids in Minsk.
Recently Published Articles
- C18-COOH Silica: Preparation, Characterisation and Its Application in Purification of Quaternary Ammonium Alkaloids from Coptis chinensis
Qing Wang, Yao Long, Lin Yao, Mao Ye and Li Xu
Version of Record online: 15 FEB 2017 | DOI: 10.1002/pca.2680
The C18-COOH silica prepared by “thiol-ene” click chemistry was employed as the solid-phase extraction sorbent to purify quaternary ammonium alkaloids from Coptis chinensis. The developed method could provide a slightly higher purification efficiency (6.7%) than an alkaloid-salt precipitation protocol (5.3%) with satisfactory reproducibility.
- Immunoaffinity knockout of saponin glycosides from Asparagus racemosus to assess anti-lipid peroxidation
Churanya Onlom, Watoo Phrompittayarat, Waraporn Putalun, Neti Waranuch and Kornkanok Ingkaninan
Version of Record online: 15 FEB 2017 | DOI: 10.1002/pca.2678
The developed immunoaffinity column coupled to monoclonal antibody recognizing shatavarin IV can isolate compounds with structures related to shatavarin IV (saponin component) from the rest (knockout component) of crude extracts of A. racemosus root. The results suggest that A. racemosus shatavarins do not inhibit carcinogenesis through preventing lipid peroxidation. The strategy described here demonstrates its utility for isolating a group of related compounds from the rest of the extract with selectivity and recovery rate.
- You have free access to this contentPrediction of Anti-Alzheimer's Activity of Flavonoids Targeting Acetylcholinesterase in silico
Subrata Das, Monjur A. Laskar, Satyajit D. Sarker, Manabendra D. Choudhury, Prakash Roy Choudhury, Abhijit Mitra, Shajarahtunnur Jamil, Siti Mariam A. Lathiff, Siti Awanis Abdullah, Norazah Basar, Lutfun Nahar and Anupam D. Talukdar
Version of Record online: 7 FEB 2017 | DOI: 10.1002/pca.2679
The authors established protocols to predict the anti-Alzheimer's activity of flavonoids targeting acetylcholinesterase by the in silico approach. The key finding is that, the 5, 7 Dihydroxy-4'-methoxy-8-prenylflavanone a flavonoid could be an efficient inhibitor of AchE and thus, could be useful in the management of Alzheimer's disease.
- Integrated HPTLC-based Methodology for the Tracing of Bioactive Compounds in Herbal Extracts Employing Multivariate Chemometrics. A Case Study on Morus alba (pages 125–131)
Eliza Chaita, Evagelos Gikas and Nektarios Aligiannis
Version of Record online: 2 FEB 2017 | DOI: 10.1002/pca.2670
Chemometric tools supported the development of a novel HPTLC-based methodology for the tracing of tyrosinase inhibitors in Morus alba extract wood. CPC fractions were assayed for tyrosinase inhibition and analyzed with HPTLC. PLS-R algorithm was performed in order to identify the compounds with the highest contribution to the biological response. Two methodologies were developed for the generation of the dataset; one based on manual peak picking and the second based on chromatogram binning.
- You have free access to this content