Phytotherapy Research

Cover image for Vol. 29 Issue 6

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Elizabeth M. Williamson, Angelo A Izzo, Sung Hoon-Kim and Rajan Radhakrishnan

Impact Factor: 2.66

ISI Journal Citation Reports © Ranking: 2014: 25/59 (Chemistry Medicinal); 105/254 (Pharmacology & Pharmacy)

Online ISSN: 1099-1573


  1. 1 - 70
  1. Research Articles

    1. Pachymic Acid Induces Apoptosis of EJ Bladder Cancer Cells by DR5 Up-Regulation, ROS Generation, Modulation of Bcl-2 and IAP Family Members

      Jin-Woo Jeong, Won Sup Lee, Se-il Go, Arulkumar Nagappan, Jun Young Baek, Jae-Dong Lee, Su-Jae Lee, Cheol Park, Gi Young Kim, Hye Jung Kim, Gon-Sup Kim, Taeg Kyu Kwon, Chung Ho Ryu, Sung Chul Shin and Yung Hyun Choi

      Article first published online: 7 JUL 2015 | DOI: 10.1002/ptr.5402

    2. Effect of Serenoa Repens on Oxidative Stress, Inflammatory and Growth Factors in Obese Wistar Rats with Benign Prostatic Hyperplasia

      Juventino III Colado-Velázquez, Patrick Mailloux-Salinas, JML Medina-Contreras, David Cruz-Robles and Guadalupe Bravo

      Article first published online: 24 JUN 2015 | DOI: 10.1002/ptr.5406

    3. Paris Saponin VII Inhibits the Migration and Invasion in Human A549 Lung Cancer Cells

      Lei Fan, Yuhua Li, Yang Sun, Jing Han, Zhenggang Yue, Jin Meng, Xutao Zhang, Feng Zhang and Qibing Mei

      Article first published online: 24 JUN 2015 | DOI: 10.1002/ptr.5389

    4. Consumption of Argan Oil Improves Anti-Oxidant and Lipid Status in Hemodialysis Patients

      Rachid Eljaoudi, Driss Elkabbaj, Abdelali Bahadi, Azeddine Ibrahimi, Mohammed Benyahia and Mourad Errasfa

      Article first published online: 23 JUN 2015 | DOI: 10.1002/ptr.5405

    5. Anti-TNF-α Activity of Brazilian Medicinal Plants and Compounds from Ouratea semiserrata

      Priscilla R. V. Campana, Daniel S. Mansur, Grasielle S. Gusman, Daneel Ferreira, Mauro M. Teixeira and Fernão C. Braga

      Article first published online: 22 JUN 2015 | DOI: 10.1002/ptr.5401

    6. Blood Glucose-lowering Effect of T. procumbens L.: A Pilot Clinical Study in Individuals with Type 2 Diabetes

      Gauri S. Desai, Shirish V. Desai, Rajendra S. Gavaskar, Vanisree Mulabagal, Yonnie Wu and Suresh T. Mathews

      Article first published online: 22 JUN 2015 | DOI: 10.1002/ptr.5394

    7. Salicin from Willow Bark can Modulate Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells

      Ute Wölfle, Birgit Haarhaus, Astrid Kersten, Bernd Fiebich, Martin J. Hug and Christoph M. Schempp

      Article first published online: 19 JUN 2015 | DOI: 10.1002/ptr.5400

  2. Tributes

    1. Obituary

      Article first published online: 18 JUN 2015 | DOI: 10.1002/ptr.5403

  3. Research Articles

    1. Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis

      Jin-Hui Song, Li Cui, Li-Bin An, Wen-Tao Li, Zhong-Ze Fang, Yan-Yan Zhang, Pei-Pei Dong, Xue Wu, Li-Xuan Wang, Frank J. Gonzalez, Xiao-Yu Sun and De-Wei Zhao

      Article first published online: 18 JUN 2015 | DOI: 10.1002/ptr.5395

    2. Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke-induced Gastric Epithelial–Mesenchymal Transition in Mice

      Zhaofeng Liang, Rui Wu, Wei Xie, Hao Geng, Li Zhao, Chunfeng Xie, Jieshu Wu, Shanshan Geng, Xiaoting Li, Mingming Zhu, Weiwei Zhu, Jianyun Zhu, Cong Huang, Xiao Ma, Caiyun Zhong and Hongyu Han

      Article first published online: 14 JUN 2015 | DOI: 10.1002/ptr.5398

    3. Schisandrin C Ameliorates Learning and Memory Deficits by Aβ1–42-induced Oxidative Stress and Neurotoxicity in Mice

      Xin Mao, Zhengzheng Liao, Lin Guo, Xuan Xu, Bo Wu, Mengjie Xu, Xu Zhao, Kaishun Bi and Ying Jia

      Article first published online: 14 JUN 2015 | DOI: 10.1002/ptr.5390

    4. 6-Acetoxy Cyperene, a Patchoulane-type Sesquiterpene Isolated from Cyperus rotundus Rhizomes Induces Caspase-dependent Apoptosis in Human Ovarian Cancer Cells

      Ji-Hye Ahn, Tae-won Lee, Ki-Hee Kim, Hoyong Byun, Byeol Ryu, Kyung-Tae Lee, Dae Sik Jang and Jung-Hye Choi

      Article first published online: 10 JUN 2015 | DOI: 10.1002/ptr.5385

  4. Reviews

  5. Research Articles

    1. Tyrosinase and Cholinesterase Inhibitory Potential and Flavonoid Characterization of Viola odorata L. (Sweet Violet)

      Ilkay Erdogan Orhan, Fatma Sezer Senol, Sinem Aslan Erdem, I. Irem Tatli, Murat Kartal and Sevket Alp

      Article first published online: 9 JUN 2015 | DOI: 10.1002/ptr.5378

    2. Alpinia katsumadai Extracts Inhibit Adhesion and Invasion of Campylobacter jejuni in Animal and Human Foetal Small Intestine Cell Lines

      Maja Šikić Pogačar, Anja Klančnik, Franz Bucar, Tomaž Langerholc and Sonja Smole Možina

      Article first published online: 9 JUN 2015 | DOI: 10.1002/ptr.5396

    3. Umbelliferone Improves an Impaired Glucose and Lipid Metabolism in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Rats

      Jarinyaporn Naowaboot, Nuntiya Somparn, Suphaket Saentaweesuk and Patchareewan Pannangpetch

      Article first published online: 8 JUN 2015 | DOI: 10.1002/ptr.5392

    4. Inhibition of Osteoclast Differentiation by Ginsenoside Rg3 in RAW264.7 Cells via RANKL, JNK and p38 MAPK Pathways Through a Modulation of Cathepsin K: An In Silico and In Vitro Study

      Muhammad Hanif Siddiqi, Muhammad Zubair Siddiqi, Sera Kang, Hae Yong Noh, Sungeun Ahn, Shakina Yesmin Simu, Mohamed Antar Aziz, Natarajan Sathishkumar, Zuly Elizabeth Jiménez Pérez and Deok-Chun Yang

      Article first published online: 8 JUN 2015 | DOI: 10.1002/ptr.5374

    5. Quercus Suber L. Cork Extracts Induce Apoptosis in Human Myeloid Leukaemia HL-60 Cells

      Ignacio Bejarano, Belén Godoy-Cancho, Lourdes Franco, Manuel A. Martínez-Cañas and María A. Tormo

      Article first published online: 5 JUN 2015 | DOI: 10.1002/ptr.5364

  6. Reviews

    1. You have full text access to this OnlineOpen article
  7. Research Articles

    1. Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells

      Elena Grossini, Patrizia Marotta, Serena Farruggio, Lorenzo Sigaudo, Fatima Qoqaiche, Giulia Raina, Veronica de Giuli, David Mary, Giovanni Vacca and Federica Pollastro

      Article first published online: 29 MAY 2015 | DOI: 10.1002/ptr.5386

    2. Inhibition of Myeloid Cell Leukemia 1 and Activation of Caspases Are Critically Involved in Gallotannin-induced Apoptosis in Prostate Cancer Cells

      Eunkyung Park, Hee Young Kwon, Ji Hoon Jung, Deok-Beom Jung, Arong Jeong, Jinhong Cheon, Bonglee Kim and Sung-Hoon Kim

      Article first published online: 27 MAY 2015 | DOI: 10.1002/ptr.5371

  8. Letters to the Editors

  9. Research Articles

    1. Transcriptomic Analysis Reveals Wound Healing of Morus alba Root Extract by Up-Regulating Keratin Filament and CXCL12/CXCR4 Signaling

      Kang-Hoon Kim, Won-Seok Chung, Yoomi Kim, Ki-Suk Kim, In-Seung Lee, Ji Young Park, Hyeon-Soo Jeong, Yun-Cheol Na, Chang-Hun Lee and Hyeung-Jin Jang

      Article first published online: 25 MAY 2015 | DOI: 10.1002/ptr.5375

  10. Reviews

  11. Research Articles

    1. Cardioprotective Effects of Tannic Acid on Isoproterenol-Induced Myocardial Injury in Rats: Further Insight into ‘French Paradox’

      Xitian Hu, Hua Wang, Xinhu Lv, Li Chu, Zhenyi Liu, Xiaogang Wei, Qincong Chen, Lei Zhu and Wei Cui

      Article first published online: 20 MAY 2015 | DOI: 10.1002/ptr.5376

    2. You have full text access to this OnlineOpen article
      An Effect of Oak-Wood Extract (Robuvit®) on Energy State of Healthy Adults—A Pilot Study

      Zuzana Országhová, Iveta Waczulíková, Carolina Burki, Peter Rohdewald and Zdeňka Ďuračková

      Article first published online: 18 MAY 2015 | DOI: 10.1002/ptr.5368

    3. Curcumin Reactivates Silenced Tumor Suppressor Gene RARβ by Reducing DNA Methylation

      Apei Jiang, Xuemin Wang, Xiaoyun Shan, Yuan Li, Pengqi Wang, Pan Jiang and Qing Feng

      Article first published online: 15 MAY 2015 | DOI: 10.1002/ptr.5373

  12. Reviews

  13. Research Articles

    1. Antidiarrheal and Antispasmodic Activities of Buddleja polystachya are Mediated Through Dual Inhibition of Ca++ Influx and Phosphodiesterase Enzyme

      Najeeb-ur Rehman, Anwarul-Hassan Gilani, Aslam Khan, Maryam Nazneen, Ali A. El Gamal, Ghada A. Fawzy, Hanan Y. Al-Ati and Maged S. Abdel-kader

      Article first published online: 14 MAY 2015 | DOI: 10.1002/ptr.5367

  14. Short Communications

    1. The Influence of Aconitum carmichaelii Debx. on the Pharmacokinetic Characteristics of Main Components in Rheum palmatum L.

      Yun-xia Li, Xiao-hong Gong, Yan Li, Ruo-qi Zhang, An Yuan, Meng-jie Zhao, Dai-wen Zeng and Cheng Peng

      Article first published online: 12 MAY 2015 | DOI: 10.1002/ptr.5369

  15. Research Articles

    1. Clinical Efficacy of Andrographolide Sulfonate in the Treatment of Severe Hand, Foot, and Mouth Disease (HFMD) is Dependent upon Inhibition of Neutrophil Activation

      Tao Wen, Wenjun Xu, Lianchun Liang, Junhong Li, Xiaorong Ding, Xiao Chen, Jianhua Hu, Aiping Lv and Xiuhui Li

      Article first published online: 9 MAY 2015 | DOI: 10.1002/ptr.5361

    2. In vivo Antimalarial Activity of α-Mangostin and the New Xanthone δ-Mangostin

      Yulieth Upegui, Sara M. Robledo, Juan Fernando Gil Romero, Winston Quiñones, Rosendo Archbold, Fernando Torres, Gustavo Escobar, Bibiana Nariño and Fernando Echeverri

      Article first published online: 5 MAY 2015 | DOI: 10.1002/ptr.5362

    3. Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs

      Connie M. Remsberg, Stephanie E. Martinez, Bolanle C. Akinwumi, Hope D. Anderson, Jody K. Takemoto, Casey L. Sayre and Neal M. Davies

      Article first published online: 4 MAY 2015 | DOI: 10.1002/ptr.5363

    4. Therapeutic Effect of Supercritical CO2 Extracts of Curcuma Species with Cancer Drugs in Rhabdomyosarcoma Cell Lines

      Cheppail Ramachandran, Karl-W. Quirin, Enrique A. Escalon, Ivonne V. Lollett and Steven J. Melnick

      Article first published online: 4 MAY 2015 | DOI: 10.1002/ptr.5360

  16. Reviews

  17. Research Articles

    1. Antifungal Activity of Ellagic Acid In Vitro and In Vivo

      Zhi-Jian Li, Xin Guo, Gulina Dawuti and Silafu Aibai

      Article first published online: 28 APR 2015 | DOI: 10.1002/ptr.5340

  18. Reviews

    1. A Review: The Pharmacology of Isoliquiritigenin

      Fu Peng, Qiaohui Du, Cheng Peng, Neng Wang, Hailin Tang, Xiaoming Xie, Jiangang Shen and Jianping Chen

      Article first published online: 24 APR 2015 | DOI: 10.1002/ptr.5348

  19. Research Articles

  20. Reviews

    1. The Potential for Plant Derivatives against Acrylamide Neurotoxicity

      O. O. Adewale, J. M. Brimson, O. A. Odunola, M. A. Gbadegesin, S. E. Owumi, C. Isidoro and T. Tencomnao

      Article first published online: 17 APR 2015 | DOI: 10.1002/ptr.5353

  21. Research Articles

    1. Comparative Study of the Biological Activity of Allantoin and Aqueous Extract of the Comfrey Root

      Vesna Lj. Savić, Vesna D. Nikolić, Ivana A. Arsić, Ljiljana P. Stanojević, Stevo J. Najman, Sanja Stojanović and Ivana I. Mladenović-Ranisavljević

      Article first published online: 16 APR 2015 | DOI: 10.1002/ptr.5356

  22. Short Communications

    1. Topical Aloe Vera (Aloe barbadensis Miller) Extract Does Not Accelerate the Oral Wound Healing in Rats

      Fernanda Hack Coelho, Gabriela Salvadori, Pantelis Varvaki Rados, Alessandra Magnusson, Chris Krebs Danilevicz, Luise Meurer and Manoela Domingues Martins

      Article first published online: 16 APR 2015 | DOI: 10.1002/ptr.5352

  23. Research Articles

    1. Activation of Caspase-9/3 and Inhibition of Epithelial Mesenchymal Transition are Critically Involved in Antitumor Effect of Phytol in Hepatocellular Carcinoma Cells

      Chul-Woo Kim, Hyun Joo Lee, Ji Hoon Jung, Yoon Hyeon Kim, Deok-Beom Jung, Eun Jung Sohn, Jang Hoon Lee, Hong Jung Woo, Nam-In Baek, Young Chul Kim and Sung-Hoon Kim

      Article first published online: 16 APR 2015 | DOI: 10.1002/ptr.5342

    2. Anti-Salmonella Activity of Volatile Compounds of Vietnam Coriander

      Ken-ichi Fujita, Warinthorn Chavasiri and Isao Kubo

      Article first published online: 14 APR 2015 | DOI: 10.1002/ptr.5351

    3. In vitro and in vivo Bone-Forming Activity of Saururus chinensis Extract

      Seong-Hee Moon, Sik-Won Choi, Sang-Joon Park, Shi-Yong Ryu, Kyu-Seok Hwang, Cheol-Hee Kim and Seong Hwan Kim

      Article first published online: 14 APR 2015 | DOI: 10.1002/ptr.5349

  24. Short Communications

    1. Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress

      Miriam S. N. Hohmann, Renato D. R. Cardoso, Victor Fattori, Nilton S. Arakawa, José C. Tomaz, Norberto P. Lopes, Rubia Casagrande and Waldiceu A. Verri Jr.

      Article first published online: 8 APR 2015 | DOI: 10.1002/ptr.5350

  25. Research Articles

    1. Korean Red Ginseng Extract Enhances the Anticancer Effects of Imatinib Mesylate Through Abrogation p38 and STAT5 Activation in KBM-5 Cells

      Sang Yoon Jung, Chulwon Kim, Wan-Seok Kim, Seok-Geun Lee, Jun-Hee Lee, Bum Sang Shim, Sung-Hoon Kim, Kyoo Seok Ahn and Kwang Seok Ahn

      Article first published online: 8 APR 2015 | DOI: 10.1002/ptr.5347

    2. Some South African Rubiaceae Tree Leaf Extracts Have Antimycobacterial Activity Against Pathogenic and Non-pathogenic Mycobacterium Species

      Abimbola O. Aro, Jean P. Dzoyem, Tiny M. Hlokwe, Evelyn Madoroba, Jacobus N. Eloff and Lyndy J. McGaw

      Article first published online: 8 APR 2015 | DOI: 10.1002/ptr.5338

    3. Effect of Silymarin Administration on Cisplatin Nephrotoxicity: Report from A Pilot, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

      Foroud Shahbazi, Sanambar Sadighi, Simin Dashti-Khavidaki, Farhad Shahi, Mehrzad Mirzania, Alireza Abdollahi and Mohammad-Hossein Ghahremani

      Article first published online: 7 APR 2015 | DOI: 10.1002/ptr.5345

    4. Anticonvulsant and Sedative Effects of Eudesmin isolated from Acorus tatarinowii on mice and rats

      Hao Liu, Zhi Song, Da-Guang Liao, Tian-Yi Zhang, Feng Liu, Kai Zhuang, Kui Luo, Liang Yang, Jing He and Jian-Ping Lei

      Article first published online: 7 APR 2015 | DOI: 10.1002/ptr.5337

    5. Enhanced Estrogenic Activity of Soybean Isoflavones by Coadministration of Liuwei Dihuang Pills in Ovariectomized Rats

      Baogang Xie, Shuohua Zhang, Jie Liu, Xuejun Zhan, Daze Xie and Zhirong Zhang

      Article first published online: 31 MAR 2015 | DOI: 10.1002/ptr.5346

    6. Inhibitory Effects of (2′R)-2′,3′-dihydro-2′-(1-hydroxy-1-methylethyl)-2,6′-bibenzofuran-6,4′-diol on Mushroom Tyrosinase and Melanogenesis in B16-F10 Melanoma Cells

      Jing-jie Zhu, Gui-rui Yan, Zhi-jian Xu, Xiao Hu, Gai-hong Wang, Ting Wang, Wei-liang Zhu, Ai-jun Hou and He-yao Wang

      Article first published online: 31 MAR 2015 | DOI: 10.1002/ptr.5344


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