Phytotherapy Research

Cover image for Vol. 28 Issue 4

Edited By: Elizabeth M. Williamson, Angelo A Izzo, Sung Hoon-Kim and Rajan Radhakrishnan

Impact Factor: 2.068

ISI Journal Citation Reports © Ranking: 2012: 33/59 (Chemistry Medicinal); 145/261 (Pharmacology & Pharmacy)

Online ISSN: 1099-1573

Author Guidelines

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Author Guidelines

Phytotherapy Research is a monthly, international journal for the publication of original research papers, short communications, reviews and letters on medicinal plant research. Key areas of interest are pharmacology, toxicology, and the clinical applications of herbs and natural products in medicine, from case histories to full clinical trials, including studies of herb-drug interactions and other aspects of the safety of herbal medicines. Papers concerned with the effects of common food ingredients and standardised plant extracts, including commercial products, are particularly welcome, as are mechanistic studies on isolated natural products.

Short communications dealing with the pharmacology and screening of crude or uncharacterised extracts will be considered for publication only if they are clearly of interest to our international readership and are not deemed more suitable for a regional audience.

Phytotherapy Research does not publish agricultural, phytochemical, structure elucidation, quality control or botanical identification papers unless directly pertinent to the pharmacological effects or overall safety of plant based medicines currently in use.

Manuscript Submission. Phytotherapy Research operates an online submission and peer review system that allows authors to submit articles online and track their progress via a web interface. Please read the remainder of these instructions to authors and then click to navigate to the Phytotherapy Research online submission site.

All papers must be submitted via the online system.

Authors are welcome to submit the names and contact details of up to three suggested reviewers, using the online system. Submission of a manuscript will be held to imply that it contains original unpublished work and is not being submitted for publication elsewhere at the same time.

File types. Preferred formats for the text and tables of your manuscript are *.doc, *.docx and *.rtf. Figures must be provided in *.tiff or *.eps format.

Upon acceptance, authors must supply by e-mail to the Production Editor: permission grants, quoting the manuscript code. If the manuscript contains extracts, including illustrations, from other copyright works (including material from on-line or intranet sources) it is the author's responsibility to obtain written permission from the owners of the publishing rights to reproduce such extracts using the Wiley Permission Request Form.

Manuscript Style. The language of the journal is English. Please ensure that your manuscript has been checked by an English language expert if there is concern for grammatical or other errors. All submissions including book reviews must have a title, be double-line spaced with type no smaller than 12 point, and have a margin of 3cm all round. Tables must be on separate pages after the reference list, and not be incorporated into the main text. Figures should be uploaded as separate Image files.

  • The title page must list the full title, short title of up to 60 characters and names and affiliations of all authors. Give the full address, including email, telephone and fax, of the author who is to check the proofs.
  • Include the name(s) of any sponsor(s) of the research contained in the paper, along with grant number(s).
  • Supply an abstract of up to 200 words for all articles. An abstract is a concise summary of the whole paper, not just the conclusions, and is understandable without reference to the rest of the paper. It should contain no citation to other published work.
  • Include up to six keywords that describe your paper for indexing purposes.
  • Authors may suggest up to 3 potential reviewers
  • A concise introduction is required of the background to the subject, its significance and its relationship to earlier works, with references.
  • Materials and methods should be presented with clarity and detail. State the original and important findings in the results. Illustrate these with figures or tables where necessary but keep these to a minimum.
  • Results and discussion may be combined as one section. Discuss the principal conclusions drawn from the results and their important implications.
  • Convention on biodiversity. Authors must indicate that they have obtained authority to access plant samples (other than freely available commercial crops or herbal products) used for research and that this has been authorised by the appropriate agent of the government of the source country as required under the framework of the United Nations Convention on Biodiversity.
  • Botanical aspects. Plant materials used must be adequately described using the Latin binomial for the plant, author of the name, plant family, source (e.g. country and region of collection, name of the collector and collection number) means of unambiguous identification (e.g. name and affiliation of expert botanist or the results of comparison with a published monograph and/or authenticated reference specimen). The reference number and place of deposition of a voucher specimen of the plant material must be given. For papers relating to crude plant extracts, the method of extraction and the yield of dried extract as a percentage weight of the starting fresh or dried plant material must also be stated. These should be submitted as short communications (see below).
  • Experimental procedures. Bioassay data for plant extracts or isolated compounds must be accompanied by data for positive and negative controls. All animal experiments should be conducted in accordance with the UK Animals (Scientific Procedures) Act 1986 and associated guidelines, the EEC Directive of 1986 (86/609/EEC) or the NIH guide for the care and use of laboratory animals (NIH Publication No. 80-23; revised 1978). The Editors will reject papers if there is any doubt about the suitability of the animal procedures used.
  • Use Chemical Abstracts nomenclature for chemical names and structures. Use proper or proprietary names with caution. Common acronyms for biomedical names are acceptable but define all others when first mentioned. Define abbreviations when first mentioned and do not use in the title or abstract. Define non-standard units.
  • Keep acknowledgements brief and place them at the end of the paper.

Original Papers. These should not exceed five printed pages including a maximum of four figures and/or four tables and 30 references, (where one page comprises 800 words or the equivalent in illustrative and tabular material).

Short Communications. These must be complete, self-contained papers, and not preliminary reports. These should not exceed two printed pages including a maximum of two figures and/or two tables and 10 references. To exceed the limit may delay acceptance or publication of the paper.

Reviews and Keynote Lecture Transcripts. These will usually be written at the invitation of the Editors. Unsolicited reviews and manuscripts based on Conference Keynote Lectures will be welcome but authors wishing to submit these are requested to consult the Editor beforehand, ideally prior to commencement of writing. Reviews should include a Table of Contents and will normally be limited to 10,000 words including references and should be submitted via the online system.

Correspondence. Items submitted for the correspondence columns, which need have no fixed format are intended for constructive comments on published work or for putting forward new ideas and are published at the discretion of the Editors.

Pre-Submission English Language Editing Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at Japanese authors can also find a list of local English improvement services at All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Reference style. References should be quoted in the text as name and year, and listed at the end of the paper alphabetically. All references must be complete and accurate. Phytotherapy Research uses Index Medicus Style abbreviations for journals cited. For correct abbreviations visit If necessary, cite unpublished or personal work in the text but do not include it in the reference list. References should be listed in the following style:

Journals: Wright CW, Phillipson JD. 1990. Natural products and the development of selective antiprotozoal drugs. Phytother Res 4: 127-139.

Books: Wagner H, Bladt S. 1996. Plant Drug Analysis: A Thin Layer Chromatography Atlas (2nd edn). Springer-Verlag: Berlin Heidelberg.

Chapters in Books: Kips RH. 1985. Environmental aspects. In Pesticide Application: Principles and Practice , Haskel PT (ed). Oxford University Press: Oxford; 1-34.

Illustrations. Upload each figure as a separate file in either .tiff or .eps format, with the lead author's name, the figure number and the top of the figure indicated. Compound figures e.g. 1a, b, c should be uploaded as one figure. Tints are not acceptable. Lettering must be of a reasonable size that would still be clearly legible upon reduction, and consistent within each figure and set of figures. Please supply artwork at the intended size for printing, sized to the text width of 84mm/single column, 176mm/double column.Where a key to symbols is required, please include this in the artwork itself, not in the figure legend. All illustrations must be supplied at the correct resolution:

  • Black and white and colour photos - 300 dpi
  • Graphs, drawings, etc. - 800 dpi preferred; 600 dpi minimum
  • Combinations of photos and drawings (black and white and colour) - 500 dpi

The cost of printing colour illustrations in the journal will be charged to the author. If colour illustrations are supplied electronically in either TIFF or EPS format, they may be used in the PDF of the article at no cost to the author, even if this illustration was printed in black and white in the journal. The PDF will appear on the Wiley Online Library site.

OnlineOpen. OnlineOpen is available to authors of articles who wish to make their article open access. With OnlineOpen the author, their funding agency, or institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in PubMed Central and PMC mirror sites. In addition to publication online via Wiley Online Library, authors of OnlineOpen articles are permitted to post the final, published PDF of their article on a website, institutional repository, or other free public server, immediately on publication.

Copyright Transfer Agreement. If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement. If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen. If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

Further Information. Proofs will be sent to the author for checking. This stage is to be used only to correct errors that may have been introduced during the production process. Prompt return of the corrected proofs, preferably within two days of receipt, will minimise the risk of the paper being held over to a later issue. Free access to the final PDF offprint of your article will be available via Author Services only (unless otherwise stated). Please therefore sign up for Author Services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers. Reprints of your article and copies of the journal may be ordered. There is no page charge to authors.

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PEER Project

This journal is participating in the PEER Project, an EU-funded initiative to examine the impact on scholarly journals of depositing accepted manuscripts in web-based repositories. If the corresponding author is based in an EU country, we will deposit the accepted manuscript into a central project repository (DRIVER). The article's availability will be subject to a post-publication embargo. This project has no effect on your rights or obligations under the terms of the copyright agreement pertaining to this journal.

Conflict of Interest. All authors must declare financial/commercial conflicts of interest. Even if there is none, this should be stated in a separate paragraph following on from the Acknowledgements section. This is a mandatory requirement for all articles.