ChemBioChem

Cover image for Vol. 15 Issue 13

Editor: Peter Gölitz; Editorial Board Chairs: Thomas Carell, Donald Hilvert, Barbara Imperiali

Online ISSN: 1439-7633

Associated Title(s): ChemCatChem, ChemMedChem, ChemPhysChem, ChemSusChem

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Here's a selection of upcoming papers. Also see the EarlyView page for the latest papers published online.

Unnatural Polyketide Analogues Selectively Target the HER Signaling Pathway in Human Breast Cancer Cells
[Full Paper]

Seok Joon Kwon, Moon Il Kim, Bosung Ku, Lydie Coulombel, Jin-Hwan Kim, Joseph H. Shawky, Robert J. Linhardt, Jonathan S. Dordick*

Coming soon.

Multiplexed Programmable Release of Captured DNA
[Communication]

Julia Kennedy-Darling, Matthew T. Holden, Michael R. Shortreed, Lloyd M. Smith*

Coming soon.

Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases
[Full Paper]

Michaela Mačková, Radek Pohl, Michal Hocek*

Coming soon.

Traceless Semisynthesis of a Set of Histone 3 Species Bearing Specific Lysine Methylation Marks
[Communication]

Zhonglei Chen, Adrian T. Grzybowski, Alexander J. Ruthenburg*

Published online on August 22, 2014.
DOI: 10.1002/cbic.201402313

Synergistic Actions of Tailoring Enzymes in Pradimicin Biosynthesis
[Full Paper]

Kandy Napan, Shuwei Zhang, Whitney Morgan, Thomas Anderson, Jon Y. Takemoto, Jixun Zhan*

Published online on August 22, 2014.
DOI: 10.1002/cbic.201402306

Site-Specific Modification of the Anticancer and Antituberculosis Polyether Salinomycin by Biosynthetic Engineering
[Communication]

Hanna Luhavaya, Simon R. Williams, Hui Hong, Luciana Gonzaga de Oliveira, Peter F. Leadlay*

Published online on August 22, 2014.
DOI: 10.1002/cbic.201402300

Fast Reversibility of Dimeriser System enables Quantification of Signal Molecule Turnover
[Highlight]

Merel J. W. Adjobo-Hermans*

Published online on August 21, 2014.
DOI: 10.1002/cbic.201402294

Chemoenzymatic Synthesis of Trehalose Analogues: Rapid Access to Chemical Probes for Investigating Mycobacteria
[Communication]

Bailey L. Urbanek, Douglas C. Wing, Krystal S. Haislop, Chelsey J. Hamel, Rainer Kalscheuer, Peter J. Woodruff, Benjamin M. Swarts*

Published online on August 25, 2014.
DOI: 10.1002/cbic.201402288

PNA-Encoded Synthesis (PES) of a 10 000-Member Hetero-Glycoconjugate Library and Microarray Analysis of Diverse Lectins
[Communication]

Alexandre Novoa, Takuya Machida, Sofia Barluenga, Anne Imberty*, Nicolas Winssinger*

Coming soon.

Expanded Genetic Code Technologies for Incorporating Modified Lysine at Multiple Sites
[Minireview]

Tatsuo Yanagisawa, Takashi Umehara, Kensaku Sakamoto, Shigeyuki Yokoyama*

Coming soon.

Short Antimicrobial Lipo-α/γ-AA Hybrid Peptides
[Full Paper]

Yaqiong Li, Christina Smith, Haifan Wu, Peng Teng, Yan Shi, Shruti Padhee, Torey Jones, Anh-My Nguyen, Chuanhai Cao, Hang Yin*, Jianfeng Cai*

Published online on August 28, 2014.
DOI: 10.1002/cbic.201402264

Ribosylhopane, a Novel Bacterial Hopanoid, as Precursor of C35 Bacteriohopanepolyols in Streptomyces coelicolor A3(2)
[Full Paper]

Wenjun Liu, Elias Sakr, Philippe Schaeffer, Helen M. Talbot, Janina Donisi, Thomas Härtner, Elmar Kannenberg, Eriko Takano, Michel Rohmer*

Published online on August 22, 2014.
DOI: 10.1002/cbic.201402261

Biofilm-Eradicating Properties of Quaternary Ammonium Amphiphiles: Simple Mimics of Antimicrobial Peptides
[Communication]

Megan C. Jennings, Laura E. Ator, Thomas J. Paniak, Kevin P. C. Minbiole*, William M. Wuest*

Published online on August 21, 2014.
DOI: 10.1002/cbic.201402254

Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE
[Full Paper]

Sheel C. Dodani, Jackson K. B. Cahn, Tillmann Heinisch, Sabine Brinkmann-Chen, John A. McIntosh, Frances H. Arnold*

Coming soon.

Quantitative Determination of Cellular Farnesyltransferase Activity: Towards Defining the Minimum Substrate Reactivity for Biologically Relevant Protein Farnesylation
[Communication]

Susan C. Flynn, Danielle E. Lindgren, James L. Hougland*

Coming soon.

Thermophiles as Potential Source of Novel Endotoxin Antagonists: the Full Structure and Bioactivity of the Lipo-oligosaccharide from Thermomonas hydrothermalis
[Full Paper]

Flaviana Di Lorenzo, Ida Paciello, Luigi Lembo Fazio, Luciana Albuquerque, Luisa Sturiale, Milton S. da Costa, Rosa Lanzetta, Michelangelo Parrilli, Domenico Garozzo, Maria Lina Bernardini, Dott. Alba Silipo, Antonio Molinaro*

Coming soon.

Piloting the Membranolytic Activities of Peptides with a Self-organizing Map
[Communication]

Yen-Chu Lin, Jan A. Hiss, Petra Schneider, Peter Thelesklaf, Yi Fan Lim, Max Pillong, Fabian M. Koehler, Petra S. Dittrich, Cornelia Halin, Silja Wessler, Gisbert Schneider*

Coming soon.

Probing Ambiguous Base-Pairs by Genetic Transformation with XNA Templates
[Full Paper]

Valérie Pezo, Guy Schepers, Catia Lambertucci, Philippe Marlière, Piet Herdewijn*

Published online on August 26, 2014.
DOI: 10.1002/cbic.201402226

Regulatory FeII/III Heme: The Reconstruction of a Molecule's Biography
[Review]

Toni Kühl*, Diana Imhof

Coming soon.

Engineering of Highly Selective Variants of Parvibaculum lavamentivorans Alcohol Dehydrogenase
[Communication]

Dominik Spickermann, Sascha Hausmann, Christian Degering, Ulrich Schwaneberg, Christian Leggewie*

Published online on August 28, 2014.
DOI: 10.1002/cbic.201402216

A Coenzyme-Independent Decarboxylase/Oxygenase Cascade for the Efficient Synthesis of Vanillin
[Full Paper]

Toshiki Furuya*, Misa Miura, Kuniki Kino*

Published online on August 27, 2014.
DOI: 10.1002/cbic.201402215

Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases
[Communication]

Philipp N. Scheller, Silvia Fademrecht, Sebastian Hofelzer, Jürgen Pleiss, Friedemann Leipold, Nicholas J. Turner, Bettina M. Nestl*, Bernhard Hauer*

Published online on August 27, 2014.
DOI: 10.1002/cbic.201402213

Heterologous Production of Glidobactins/Luminmycins in Escherichia coli Nissle Containing the Glidobactin Biosynthetic Gene Cluster from Burkholderia DSM7029
[Communication]

Xiaoying Bian, Fan Huang, Hailong Wang, Thorsten Klefisch, Rolf Müller*, Youming Zhang*

Published online on August 21, 2014.
DOI: 10.1002/cbic.201402199

Repositioning the Substrate Activity Screening (SAS) Approach as a Fragment-Based Method for Identification of Weak Binders
[Full Paper]

Rafaela Gladysz, Matthias Cleenewerck, Jurgen Joossens, Anne-Marie Lambeir, Koen Augustyns, Pieter Van der Veken*

Published online on August 25, 2014.
DOI: 10.1002/cbic.201402192

Significant Enhancement of hPrx1 Chaperone Activity through Lysine Acetylation
[Communication]

Yanchao Pan, Jing-Hua Jin, Yang Yu*, Jiangyun Wang*

Published online on August 21, 2014.
DOI: 10.1002/cbic.201402164

Low-Resolution Structures of OmpA·DDM Protein–Detergent Complexes
[Full Paper]

Jørn Døvling Kaspersen, Christian Moestrup Jessen, Brian Stougaard Vad, Esben Skipper Sørensen, Kell Kleiner Andersen, Marianne Glasius, Cristiano Luis Pinto Oliveira, Daniel Erik Otzen*, Jan Skov Pedersen*

Published online on August 19, 2014.
DOI: 10.1002/cbic.201402162

Biological Applications of Expanded Genetic Codes
[Minireview]

Xiang Li, Chang C. Liu*

Coming soon.

Lactose-Functionalized Dendrimers Arbitrate the Interaction of Galectin-3/MUC1 Mediated Cancer Cellular Aggregation
[Full Paper]

Anna K. Michel, Pratima Nangia-Makker, Avraham Raz, Mary J. Cloninger*

Published online on August 19, 2014.
DOI: 10.1002/cbic.201402134

Chemically Synthesized 58-mer LysM Domain Binds Lipochitin Oligosaccharide
[Full Paper]

Kasper K. Sørensen, Jens B. Simonsen, Nicolai N. Maolanon, Jens Stougaard, Knud J. Jensen*

Published online on August 26, 2014.
DOI: 10.1002/cbic.201402125

Peptidyl Succinimidyl Peptides as Taspase 1 Inhibitors
[Full Paper]

Johannes van den Boom, Marija Mamić, Daniele Baccelliere, Susanne Zweerink, Farnusch Kaschani, Shirley Knauer, Peter Bayer, Markus Kaiser*

Published online on August 21, 2014.
DOI: 10.1002/cbic.201402108

Hydrophobic Triaryl-Substituted β-Lactams as Activity-Based Probes for Profiling Eukaryotic Enzymes and Host–Pathogen Interactions
[Communication]

Neda Nasheri, Craig S. McKay, Kelly Fulton, Susan Twine, Megan H. Powdrill, Allison R. Sherratt, John Paul Pezacki*

Coming soon.

Synthesis of Cholesterol Analogues Bearing BODIPY Fluorophores by Suzuki or Liebeskind–Srogl Cross-Coupling and Evaluation of Their Potential for Visualization of Cholesterol Pools
[Full Paper]

Zheng Liu, Seth G Thacker, Sara Fernandez-Castillejo, Edward B. Neufeld, Alan T. Remaley, Robert Bittman*

Published online on August 22, 2014.
DOI: 10.1002/cbic.201402042

Intramolecular Thioether Crosslinking of Therapeutic Proteins to Increase Proteolytic Stability
[Full Paper]

Joel Lindgren, Amelie Eriksson Karlström*

Coming soon.

Photobleaching Reveals Heterogeneous Stoichiometry for Equinatoxin II Oligomers
[Full Paper]

Matthew A. B. Baker, Nejc Rojko, Bríd Cronin, Gregor Anderluh, Mark I. Wallace*

Published online on August 19, 2014.
DOI: 10.1002/cbic.201300799

Ion-Channel Modulators: More Diversity Than Previously Thought
[Minireview]

Sébastien Dilly*, Cédric Lamy, Neil V. Marrion, Jean-François Liégeois, Vincent Seutin

Coming soon.

RNA Grooves Can Accommodate Disulfide-Bridged Bundles of α-Helical Peptides
[Communication]

Soonsil Hyun, Jiyoung Na, Su Jin Lee, Sangeun Park, Jaehoon Yu*

Coming soon.

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