© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: A Mass Spectrometry Plate Reader: Monitoring Enzyme Activity and Inhibition with a Desorption/Ionization on Silicon (DIOS) Platform (ChemBioChem 7/2004)
The cover picture shows the laser-facilitated Desorption/Ionization on Silicon (DIOS) process that allows for intact biomolecule generation in the gas phase and high-throughput mass analyses. The DIOS platform is the basis of the mass spectrometry plate reader, described on p. 921 ff. by Z.-x. Shen, G. Siuzdak et al., for enzyme- inhibitor and enzyme-activity studies. The image was created by Z.-x. Shen.