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Inside Cover: A Chemoenzymatic Route to Diversify Aminolgycosides Enables a Microarray-Based Method to Probe Acetyltransferase Activity (ChemBioChem 12/2010)
The inside cover picture shows that a chemoenzymatic route to diversify aminoglycosides can light up antibacterial resistance on a microarray. The approach will allow for the identification of protein and carbohydrate substrates for acetyltransferases, which control antibacterial resistance and a host of other cellular process. More details may be found in the communication by M. D. Disney and co-workers on p. 1656 ff.