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Inside Cover: Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries (ChemBioChem 17/2010)
The inside cover picture shows the crystal structure and high-throughput screening procedure of pentaerythritol tetranitrate reductase (PETNR) for generating biocatalysts with altered product identity and/or enantiopurities. The lower figure shows the active site and altered biocatalytic abilities of wild-type and mutant PETNR. For more information, see the paper by N. S. Scrutton et al. on p. 2433 ff.