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Inside Cover: IspG-Catalyzed Positional Isotopic Exchange in Methylerythritol Cyclodiphosphate of the Deoxyxylulose Phosphate Pathway: Mechanistic Implications (ChemBioChem 4/2011)
The inside cover picture shows that the enzyme IspG in the deoxyxylulose phosphate pathway can mediate a reversible C-O bond cleavage at an inert position. This hypothesis was supported by the detection of diphosphate ester bridging and terminal oxygen atom exchange. For more information, see the communication by P.-h. Liu et al. on p. 527 ff.