Cover image for Vol. 18 Issue 12

Editor: Meghan Campbell; Editorial Board Chairs: Thomas Carell, Donald Hilvert, Barbara Imperiali

Online ISSN: 1439-7633

Associated Title(s): ChemCatChem, ChemMedChem, ChemPhysChem, ChemSusChem

13_16i/2012Inside Cover: Exclusively Heteronuclear 13C-Detected Amino-Acid-Selective NMR Experiments for the Study of Intrinsically Disordered Proteins (IDPs) (ChemBioChem 16/2012)

The inside cover picture shows how “spin gymnastics” can be used to “avoid the crowd”. A major problem with the NMR spectra of intrinsically disordered proteins is the chemical shift dispersion arising from their high flexibility and lack of unique 3D structure. On p. 2425 ff., I. C. Felli, R. Pierattelli, et al. present a strategy for drastically reducing crosspeak overlap by conducting amino-acid-selective 13C NMR experiments (CAS-NMR).

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