ChemBioChem

Cover image for Vol. 18 Issue 10

Editor: Meghan Campbell; Editorial Board Chairs: Thomas Carell, Donald Hilvert, Barbara Imperiali

Online ISSN: 1439-7633

Associated Title(s): ChemCatChem, ChemMedChem, ChemPhysChem, ChemSusChem

13_17i/2012Inside Cover: A Peptide Photoaffinity Probe Specific for the Active Conformation of the Abl Tyrosine Kinase (ChemBioChem 17/2012)

The inside cover picture shows a peptide photoaffinity label modeled into the active site of the Abl tyrosine kinase. On p. 2510 ff., B. E. Turk et al. show that probes based on Abl substrates label only the active conformation of the kinase. These probes can be used to monitor Abl in complex mixtures and to decipher the mechanisms of action of small-molecule Abl inhibitors.

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