Cover image for Vol. 18 Issue 14

Editor: Meghan Campbell; Editorial Board Chairs: Thomas Carell, Donald Hilvert, Barbara Imperiali

Online ISSN: 1439-7633

Associated Title(s): ChemCatChem, ChemMedChem, ChemPhysChem, ChemSusChem

October 04, 2004

Nobel Prize in Medicine/Physiology to Richard Axel and Linda B. Buck

Richard Axel (Columbia University, New York, USA) and Linda B. Buck (Fred Hutchinson Cancer Research Center, Seattle, WA, USA) were awarded the 2004 Nobel Prize in Physiology or Medicine for for their discoveries of odorant receptors and the organization of the olfactory system. They discovered a large gene family, comprised of some 1,000 different genes (three per cent of our genes) that give rise to an equivalent number of olfactory receptor types. These receptors are located on the olfactory receptor cells, which occupy a small area in the upper part of the nasal epithelium and detect the inhaled odorant molecules.

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