© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor: Greta Heydenrych; Editorial Board Chairs: Christian Amatore, Michael Grätzel, Michel Orrit
Impact Factor: 3.138
ISI Journal Citation Reports © Ranking: 2015: 8/35 (Physics Atomic Molecular & Chemical); 50/144 (Chemistry Physical)
Online ISSN: 1439-7641
Cover Picture: Monitoring Protein Interactions in the Living Cell Through the Fluorescence Decays of the Cyan Fluorescent Protein (ChemPhysChem 7/2006)
The cover picture shows how the fluorescence decays of the cyan fluorescent protein (CFP) can reveal molecular interactions and organisation in the living cell. Förster resonant energy transfer (FRET) towards its acceptor, the yellow fluorescent protein (YFP), leads to charateristic decreases in the CFP fluorescence lifetimes. Despite the very high intracellular protein concentrations achieved, leading to strong molecular proximity, the results show that CFP and YFP fail to form inside the cell the dimer, previously observed for purified green fluorescent proteins. Find out more in the Article by Grailhe et al. on page 1442.