Protein Science

Cover image for Vol. 24 Issue 7

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Brian W. Matthews

Impact Factor: 2.854

ISI Journal Citation Reports © Ranking: 2014: 136/289 (Biochemistry & Molecular Biology)

Online ISSN: 1469-896X


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  1. Full-Length Papers

    1. Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design

      Andrew P. Ah Young, Antoine Koehl, Duilio Cascio and Pascal F. Egea

      Accepted manuscript online: 30 JUN 2015 06:02PM EST | DOI: 10.1002/pro.2739

    2. An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication

      Dominik Barthelme, Ruben Jauregui and Robert T. Sauer

      Accepted manuscript online: 30 JUN 2015 06:01PM EST | DOI: 10.1002/pro.2740

    3. Comparison of Intrinsic Dynamics of Cytochrome P450 Proteins Using Normal Mode Analysis

      Mariah E. Dorner, Ryan D. McMunn students of Biophysical Chemistry Course (Fall 2013) and Sanchita Hati

      Accepted manuscript online: 30 JUN 2015 10:51AM EST | DOI: 10.1002/pro.2737

    4. Estimating First Passage Time Distributions from Weighted Ensemble Simulations and non-Markovian Analyses

      Ernesto Suárez, Adam J. Pratt, Lillian T. Chong and Daniel M. Zuckerman

      Accepted manuscript online: 30 JUN 2015 10:31AM EST | DOI: 10.1002/pro.2738

    5. Organization of the multiaminoacyl-tRNA synthetase complex and the co-translational protein folding

      Igor N. Berezovsky, Zejun Zheng, Atsushi Kurotani, Alexander A. Tokmakov and Igor V. Kurochkin

      Accepted manuscript online: 30 JUN 2015 03:53AM EST | DOI: 10.1002/pro.2735

    6. Linking structural features of protein complexes and biological function

      Gopichandran Sowmya, Edmond J. Breen and Shoba Ranganathan

      Accepted manuscript online: 30 JUN 2015 03:51AM EST | DOI: 10.1002/pro.2736

    7. Engineering Trypsin for Inhibitor Resistance

      Anna R. Batt, Commodore P. St. Germain, Trevor Gokey, Anton B. Guliaev and Teaster Baird Jr.

      Accepted manuscript online: 24 JUN 2015 02:29AM EST | DOI: 10.1002/pro.2732

  2. Methods and Applications

    1. Covalent Docking using Autodock: Two-Point Attractor and Flexible Sidechain Methods

      Giulia Bianco, Stefano Forli, David S. Goodsell and Arthur J. Olson

      Accepted manuscript online: 24 JUN 2015 02:29AM EST | DOI: 10.1002/pro.2733

  3. Reviews

    1. Structure-Function Correlations in Tyrosinases

      Margarita Kanteev, Mor Goldfeder and Ayelet Fishman

      Accepted manuscript online: 24 JUN 2015 02:29AM EST | DOI: 10.1002/pro.2734

  4. Full-Length Papers

    1. Computational Study of the W260A Activating Mutant of Src Tyrosine Kinase

      Yilin Meng and Benoît Roux

      Accepted manuscript online: 24 JUN 2015 02:29AM EST | DOI: 10.1002/pro.2731

    2. Effect of single point mutations in a form of systemic amyloidosis

      Manikanthan Bhavaraju and Ulrich H.E. Hansmann

      Accepted manuscript online: 24 JUN 2015 02:27AM EST | DOI: 10.1002/pro.2730

    3. Structural Basis of the Broadly Neutralizing anti-Interferon-α Antibody Rontalizumab

      Brigitte Maurer, Ivan Bosanac, Steven Shia, Mandy Kwong, Racquel Corpuz, Richard Vandlen, Kerstin Schmidt and Charles Eigenbrot

      Accepted manuscript online: 22 JUN 2015 02:02AM EST | DOI: 10.1002/pro.2729

    4. Extracting intrinsic dynamic parameters of biomolecular folding from single-molecule force spectroscopy experiments

      Gi-Moon Nam and Dmitrii E Makarov

      Accepted manuscript online: 19 JUN 2015 03:10AM EST | DOI: 10.1002/pro.2727

    5. You have full text access to this OnlineOpen article
      Comparison of topological clustering within protein networks using edge metrics that evaluate full sequence, full structure, and active site microenvironment similarity

      Janelle B. Leuthaeuser, Stacy T. Knutson, Kiran Kumar, Patricia C. Babbitt and Jacquelyn S. Fetrow

      Accepted manuscript online: 12 JUN 2015 11:25AM EST | DOI: 10.1002/pro.2724

    6. Influence of diffusion on the kinetics of multisite phosphorylation

      Irina V. Gopich and Attila Szabo

      Accepted manuscript online: 10 JUN 2015 06:08PM EST | DOI: 10.1002/pro.2722

  5. Full-xLength Papers

    1. Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction

      Jason H. Whitfield, William Zhang, Michel K. Herde, Ben E. Clifton, Johanna Radziejewski, Harald Janovjak, Christian Henneberger and Colin J. Jackson

      Accepted manuscript online: 9 JUN 2015 06:16PM EST | DOI: 10.1002/pro.2721

  6. Full-Length Papers

    1. Impact of cysteine variants on the structure, activity, and stability of recombinant human α-galactosidase A

      Huawei Qiu, Denise M. Honey, Jonathan S. Kingsbury, Anna Park, Ekaterina Boudanova, Ronnie Wei, Clark Q. Pan and Tim Edmunds

      Accepted manuscript online: 5 JUN 2015 01:59AM EST | DOI: 10.1002/pro.2719

  7. Methods and Applications

    1. Electron-capture dissociation and ion mobility mass spectrometry for characterization of the hemoglobin protein assembly

      Weidong Cui, Hao Zhang, Robert E. Blankenship and Michael L. Gross

      Accepted manuscript online: 1 JUN 2015 03:59AM EST | DOI: 10.1002/pro.2712

  8. Full-Length Papers

    1. You have full text access to this OnlineOpen article
      EsxB, a secreted protein from Bacillus anthracis forms two distinct helical bundles

      Yao Fan, Kemin Tan, Gekleng Chhor, Emily K. Butler, Robert P. Jedrzejczak, Dominique Missiakas and Andrzej Joachimiak

      Accepted manuscript online: 1 JUN 2015 03:59AM EST | DOI: 10.1002/pro.2715

    2. Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase

      Yu-ming M. Huang, Wanli You, Bethany G. Caulkins, Michael F. Dunn, Leonard J. Mueller and Chia-en A. Chang

      Accepted manuscript online: 26 MAY 2015 06:32PM EST | DOI: 10.1002/pro.2709

    3. A unique binding mode of the eukaryotic translation initiation factor 4E for guiding the design of novel peptide inhibitors

      Daniele Di Marino, Ilda D'Annessa, Holly Tancredi, Claudia Bagni and Emilio Gallicchio

      Accepted manuscript online: 26 MAY 2015 06:32PM EST | DOI: 10.1002/pro.2708

    4. An integrative approach combining ion mobility mass spectrometry, X-ray crystallography and NMR spectroscopy to study the conformational dynamics of α1-antitrypsin upon ligand binding

      Mun Peak Nyon, Tanya Prentice, Jemma Day, John Kirkpatrick, Ganesh N. Sivalingam, Geraldine Levy, Imran Haq, James A. Irving, David A. Lomas, John Christodoulou, Bibek Gooptu and Konstantinos Thalassinos

      Accepted manuscript online: 26 MAY 2015 03:22AM EST | DOI: 10.1002/pro.2706


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