Copyright © 2013 Wiley Periodicals, Inc
Edited By: Prof. John Caldwell and Prof. Nina D. Berova
Impact Factor: 1.894
ISI Journal Citation Reports © Ranking: 2012: 32/57 (Chemistry Organic); 34/59 (Chemistry Medicinal); 41/75 (Chemistry Analytical); 161/261 (Pharmacology & Pharmacy)
Online ISSN: 1520-636X
Effective with the 2014 volume, this journal will be published in an online-only format.
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Author Services – Online production tracking is now available for your article through Wiley Blackwell's Author Services.
Author Services enables authors to track their article - once it has been accepted - through the production process to publication online. Authors can check the status of their articles online and choose to receive automated emails at key stages of production. The author will receive an email with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete email address is provided when submitting the manuscript. Visit http://authorservices.wiley.com for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.
- Author Submission Guidelines for Supplementary Material
- Wiley's Journal Styles and EndNote
- ChemDraw template for structure drawings in ChemDraw (Win/Mac)
CHIRALITY: The Pharmacological, Biological, and Chemical Consequences of Molecular Asymmetry
Prof. John Caldwell, Editor
Prof. Nina D. Berova, Editor
ONLINE MANUSCRIPT SUBMISSION
Chirality welcomes submitted manuscripts online at: http://mc.manuscriptcentral.com/chir . Online submission offers receipt of manuscript on the day of submission, expedited transfer to reviewers; status review by authors of online submissions; and e-mail notification of manuscript disposition received by the corresponding author on the day of the decision.
ScholarOne Manuscripts does not accept a single file upload from the author. Text, tables, and figures will need to be uploaded individually. Do not embed figures or tables in the document. Text format: .doc, .docx, or .rtf only. Figure format: .tif or .eps only. A delay in processing your paper for review will ensue if we have to get back to you to ask that you carry out this submission requirement.
TO SUBMIT YOUR MANUSCRIPT ONLINE:
- Please submit your manuscript online at http://mc.manuscriptcentral.com/chir .
- Click on "Check for Existing Account" . If you do not already have an account, click on "Create an Account" Be sure to enter Keywords .
- Follow instructions carefully. Please review that your submission has uploaded correctly before clicking on the "Submit" button.
- On completion of a successful submission, a confirmation screen with manuscript will appear and you will receive an e-mail confirming that the manuscript has been received by the journal. If you do not receive an email acknowledgment that your paper has been received, it means that your submission is incomplete. Please reenter the site and double-check that you have reviewed and clicked "submit" on screen twelve and/or contact tech support at firstname.lastname@example.org .
Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at www.blackwellpublishing.com/bauthor/english_language.asp. Japanese authors can also find a list of local English improvement services at http://www.wiley.co.jp/journals/editcontribute.html. All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.
Title Page. This must contain: (1) complete title of the manuscript; (2) author's name(s) must carry superscript number(s). The corresponding author should be indicated by an asterisk; (3) institutional affiliation(s) (at which the work was performed) must be listed at the departmental level. Each distinct affiliation should be listed as a separate entity, with a superscript number that links it to the individual author(s); (4) shortened title which does not exceed 45 characters, including spaces, to be used as a running head; (5) five to ten key words not used in the title that will adequately index the subject matter of the article; (6) current and complete name, address, phone and fax numbers, and E-mail address of the corresponding author; (7) all grant information should be provided in the following format: Contract grant sponsor:__________; Contract grant number:________.
Abstract. This should summarize the purpose, methods, results, and major conclusions of the work in fewer than 200 words.
Graphical Abstract. This is used in each issue's online graphical table of contents must be included in all manuscripts. The image may be a key figure or a scheme from the text; it may be a reaction, equation, concept, etc. or an imaginative illustration of a concept described in the manuscript, preferably in color. Spectra or other analytical data are not recommended. The image will be printed square with sides not larger than 2 inches/5 cm; the use of graphs and images consisting of several parts is therefore strongly discouraged.
Introduction, Materials and Methods, Results, Discussion, and Conclusion. These should conform to standard scientific reporting style. Sufficient data must be given so that the study can be replicated. It may be appropriate to combine the Results and Discussion.
Wiley's Journal Styles Are Now in EndNote
EndNote is a software product that we recommend to our journal authors to help simplify and streamline the research process. Using EndNote's bibliographic management tools, you can search bibliographic databases, build and organize your reference collection, and then instantly output your bibliography in any Wiley journal style.
Download Reference Style for this Journal: If you already use EndNote, you can download the reference style for this journal.
How to Order: To learn more about EndNote, or to purchase your own copy, click here .
Technical Support: If you need assistance using EndNote, contact email@example.com , or visit www.endnote.com/support .
References to published literature should be cited in the text numerically. Reference should be made only to articles that are published or in press. Unpublished results and personal communications should be cited parenthetically in the text and should not be included in the Reference list. Authors are responsible for the accuracy of the references. It is important to provide full titles and complete page ranges for all works cited in the reference section. Do not include footnote information in the References. Footnote information should either be incorporated into the text or included as a footnote to the text. If applicable, a footnote with the following statement should be included at an appropriate place in the manuscript: Crystallographic data for the structure(s) reported in this paper have been deposited with the Cambridge Crystallographic Data Centre (insert CCDC #). Copies of the data can be obtained, free of charge, on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, United Kingdom (Fax: 44-1223-336033 or e-mail: firstname.lastname@example.org).
1. King VM, Armstrong DM, Apps R, Trott JR. Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 1998;390:537-551.
When references are made to more than one paper by the same author, published in the same year, designate them as a, b, c, etc.
2. Dewar MJS, Zoebisch EG, Healy EF, Stewart JJP. AM1: A new general purpose quantum mechanical model. J Am Chem Soc 1985a;107:3902-3909.
3. Dewar MJS, Yuan Y-C. AM1 parameters for sulfur. Inorg Chem 1985b;29:3881-3890.
4. Dewar MJS, Zoebisch EG. Extension of AM1 to the halogens. THEOCHEM 1985c;49:1-21.
5. Voet D, Voet JG. Biochemistry. New York: John Wiley & Sons; 1990. 1223 p.
6. Gilmor ML, Rouse ST, Heilman CJ, Nash NR, Levey AI. Receptor fusion proteins and analysis. In: Ariano MA, editor. Receptor localization. New York: Wiley-Liss;1998. p 75-90.
Tables and Illustrations
Indicate placement of all tables and illustrations at the relevant point in the text. Tables must be numbered in order of appearance with Roman numerals; illustrations with arabic numerals. A legend must accompany each illustration (including schemes), and tables must have titles. Type double spaced. All abbreviations used must be defined. Lettering must meet professional standards and be legible after reduction in size. Do not submit original recordings, radiographic plates, or artwork. All color figures will be reproduced in full color in the online edition of the journal at no cost to authors. Authors are requested to pay the cost of reproducing color figures in print. Authors are encouraged to submit color illustrations that highlight the text and convey essential scientific information. For best reproduction, bright, clear colors should be used. Dark colors against a dark background do not reproduce well; please place your color images against a white background wherever possible.
Chemical structures should be prepared in ChemDraw either 80mm (one column) or 175mm (two column) widths. However, the one-column format should be used whenever possible as this allows greater flexibility in the layout of the manuscript. Use this ChemDraw Download or use the following settings:
|Drawing settings||Text settings|
|bond spacing||18% of length||size||12 pt|
|fixed length||17 pt|
|bond width||2 pt||Preferences|
|line width||0.75 pt||units||points|
|margin width||2 pt||tolerances||5 pixels|
|hash spacing||2.6 pt|
|bold width||2.6 pt|
Authors using different structural drawing programs should choose settings consistent with those above. Compound numbers should be bold, but not atom labels or captions.
All nonstandard abbreviations and acronyms should be spelled out at the point of first use in the abstract and the body of the text. Units of length, area, volume, weight, and time are to be abbreviated as follows:
(For Area and Volume insert the appropriate exponent)
|nm||nanometer||liter||do not abbreviate|
|µg||microgram||day||do not abbreviate|
The guidelines for stereochemical nomenclature used in this journal are presented below. For compounds which are not covered by these guidelines follow the ACS Style Guide.
Apparently Pure Stereoisomers. These must be designated by the sign of their optical rotation (when applicable) and/or by their configuration (absolute configuration in the case of enantiomerism, relative configuration in the case of diastereomerism).
The sign of the optical rotation is indicated by (+)- or (–)- placed at the very beginning of the name, i.e., before the descriptor of configuration. The signs d- and l- are not allowed as they are frequently confused with D- and L-. The prefixes "dextro" and "levo" are allowed when they form part of an established name (e.g., levodopa).
The absolute configuration of enantiomers must be given as far as known. Descriptors of absolute configuration are as follows:
• R and S defined according to the sequence rule of Cahn-Ingold-Prelog
•D and L (for amino acids and sugars)
• P and M (for helices)
The relative configuration of diastereomers must be indicated as follows:
•For -diastereomers (so-called geometrical isomers), the E and Z descriptors based on the sequence rule of CIP must be used rather than the prefixes cis and trans or syn and anti .
•For achiral diastereomers without stereogenic double bonds ( -diastereomers), be they cyclic or acyclic, adequate nomenclature, cis and trans , erythro and threo , or meso , must be used.
•For chiral s-diastereomers (cyclic or acyclic), the absolute configuration of each element of chirality should be indicated when known. If this is not the case, the relative configuration must be indicated (e.g., cis/trans, erythro/threo, endo/exo , R*/S* , / ).
(+)- (R) -warfarin
(Z) -2-methyl-2-butenoic acid
(–)- (P) -hexahelicene
(–)-(1 R ;2 R )-pseudoephedrine
Further indications can be found in the IUPAC rules or in monographs (e.g., Eliel, E.L. and Wilen, S.H., Stereochemistry of organic compounds. New York: Wiley, 1994).
Mixtures of Stereoisomers
Racemates must always be explicitly indicated as such using the prefix rac –e.g., rac -ibuprofen.
Mixtures of diastereomers must be indicated by such notation as (Z;E) - or cis- , trans- which do not imply a 50/50 mixture. When a mixture of stereoisomers has a well-defined proportion, this must be specified as in the following examples:
•( R/S :80/20)-warfarin
•( Z/E :90/10)-clopenthixol
Structural Formulas of Stereoisomers
Special attention must be given to the preparation of the structural formulas of compounds that contain stereogenic elements. For substituents that point toward or away from the observer, use flying wedges and dotted lines, respectively.
Each structural formula must be accompanied by an explicit caption indicating whether the formula implies absolute or relative configuration.
In order to expedite the publication and on-line posting of articles in Wiley Online Library, Chirality now offers electronic proofing. Corresponding authors with e-mail addresses will be sent page proofs in pdf format via e-mail. Please follow the instructions in the e-mail; contact names and numbers are given for questions, problems, or if an author wishes to receive a paper proof. A fax cover form with the Production Editor’s information is also provided for authors to fax their corrections. Please notify us of your preferred proof delivery method when submitting your final manuscript to the editorial office. Indicate in your cover letter your page proof choice: ELECTRONIC (pdf) or TRADITIONAL (paper).
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.
For authors signing the copyright transfer agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:
For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution License OAA
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA
To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.
If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.
OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.
Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at:
Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.
Instructions for Deposition of Cystallographic Data
(i) These notes concern the crystallographic data associated with organic and metal-organic structures.
(ii) Prior to submitting the manuscript to a journal the author should deposit with the Cambridge Crystallographic Data Centre (CCDC) the data corresponding to the intended publication.
Supplementary data should be deposited in CIF format, as a plain text ASCII file. The e-mail address is: email@example.com Author details and the name of the journal to which the submission is to be made should be included in the cif or an accompanying message and sent to firstname.lastname@example.org Authors should send a copy of revised CIF(s) to CCDC.
(iii) Within three working days, the CCDC will provide the author with a deposition number for each crystal structure reported in the manuscript. Each number is a 6-digit integer, e.g., CCDC 170345.
(iv) The author should submit to the journal the manuscript together with the deposition number(s).
(v) When the paper is published an appropriate footnote will be printed, for example:
"CCDC ...... contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request.cif
(vi) The deposited data will not be archived to the Cambridge Structural Database until the paper has been published. If, after 18 months, the paper has not been published, the CCDC will contact the depositor to determine what should be done with the data.
Notes for Authors : Guidance for deposition can be obtained from www.ccdc.cam.ac.uk/conts/depositing.html
Chirality authors can now publish supplementary material online in Wiley Online Library. Supplementary material may include (but is not limited to) video clips, large sections of tabular data, program code, or electronic graphical files that are otherwise not suitable for print media. When submitting material for consideration please follow the guidelines below.
Submission of Supplementary Material
Peer review: Supplementary material must be submitted at the time of peer review.
All files submitted must be accompanied by a text file named README. The README file should include the following information:
Title of Paper
Authors and their affiliations
Filename, file size, file type
Brief description of material
The data and the README file should be archived together using one of the popular archive protocols such as ZIP, TAR, GZIP, or SIT. If you have more than one piece of supplementary material, you should submit a separate archive for each, with an accompanying README file; however, if it is intended that the multiple files be downloaded as a single unit by the enduser, submit one archive and one README file.
Data file types: There are no restrictions on filetypes of the data that you submit. Please keep in mind, however, that the more universal the filetype the more accessible to the community. The use of popular compression protocols is highly encouraged. If your material is presented in PostScript format, the submission of an accompanying Adobe Acrobat PDF file is encouraged, in that event both formats will be offered to the journal's readers. In cases where PDF files do not accompany a PostScript file, only the Postscript will be offered. If necessary, accepted supplementary material may be ftp'd to: ftp.wiley.com. User name: chiral password: diff&4
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