The Journal of Gene Medicine

Cover image for Vol. 18 Issue 1-3

Edited By: Ernst Wagner and Mengfeng Li

Impact Factor: 2.472

ISI Journal Citation Reports © Ranking: 2014: 61/123 (Medicine Research & Experimental); 62/163 (Biotechnology & Applied Microbiology); 85/167 (Genetics & Heredity)

Online ISSN: 1521-2254

Author Guidelines

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Author Guidelines

Journal of Gene Medicine is committed to rapid publication of articles. It is the intention of the Editorial Office to peer review manuscripts and notify authors of the decision within four weeks. Upon acceptance, the full text is published online in 'Accepted Articles' in within eight weeks of acceptance and subsequently appears in the next available print issue.


Thank you for your interest in Journal of Gene Medicine. Please read the complete Author Guidelines carefully prior to submission, including the section on copyright. To ensure fast peer review and publication, manuscripts that do not adhere to the following instructions will be returned to the corresponding author for technical revision before undergoing peer review.

Note that submission implies that the content has not been published or submitted for publication elsewhere except as a brief abstract in the proceedings of a scientific meeting or symposium; that all authors have read and approved the content, and all authors have also declared all competing interests; and that the work complies with Ethical Policies of the journal, and has been conducted under internationally accepted ethical standards after relevant ethical review. It is highly recommended you read this policy and complete any necessary documentation prior to your submission.

Once you have prepared your submission in accordance with the Guidelines, manuscripts should be submitted online at

A manuscript may be returned to the authors without outside review if it is deemed to be outside the scope of the journal, or if it fails to meet key criteria imposed by the journal, these being to be adequately novel; to advance the field sufficiently; or to be satisfactorily controlled. This decision will be made at the Editors' discretion.

For all submission enquiries please contact the editorial office - Email:


Revised manuscripts should be submitted within three months of receiving the Editors’ decision, using the ‘create a revision’ option for the initial manuscript. They should also include a point-by-point letter specifying how the author has responded to the reviewers’ and Editors’ comments.


Review articles are typically by invitation only, however proposals are welcome and may be accepted after editorial approval. Please contact the Editorial Office with your proposal before submitting a review article.

The journal also publishes Letters to the Editor, and Responses to a Letter from the authors of original articles that are commented upon in Letters that are accepted for publication. These should be kept brief, and be written in clear and balanced language, to allow healthy scientific discourse to take place.


Pre-acceptance English-language editing
Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. Visit our site to learn about the options. All services are paid for and arranged by the author.  Please note using the Wiley English Language Editing Service does not guarantee that your paper will be accepted by this journal.

Optimising Your Article for Search Engines
Many students and researchers looking for information online will use search engines such as Google, Yahoo or similar. By optimising your article for search engines, you will increase the chance of someone finding it. This in turn will make it more likely to be viewed and/or cited in another work. We have compiled these guidelines to enable you to maximise the web-friendliness of the most public part of your article.

Manuscript style

  • All submissions must have a title page with the full title, a short title (no more than 40 characters, spaces included) and names and affiliations of all authors. Give the full address, including email, telephone and fax of the corresponding author.
  • Supply an abstract of up to 250 words. An abstract is a concise summary of the whole article, not just the conclusions, and is understandable without reference to the rest of the article. It should contain no citation to other published work. For original research papers, divide the abstract into four short paragraphs labelled: Background, Methods, Results, Conclusions.
  • Include up to six keywords that describe your paper for indexing purposes.
  • Original research papers should be structured into headed sections as follows: Title, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgements, Conflicts of Interest Statement, References. Other subsection headings within the main headings may be used, but these should be limited.
  • The Acknowledgements section must include the name(s) of any sponsor(s) of the research contained in the paper, along with grant number(s).
  • Abbreviations are not encouraged except for units of measurement and universally recognized abbreviations (e.g. DNA). When an abbreviation appears in the text for the first time, it should be placed in parentheses after the words for which it stands.

The Editor reserves the right to alter manuscripts whenever necessary to make them conform to the stylistic and bibliographical conventions of the journal.

Materials and Methods

Research reports should include all information and raw data necessary to allow others to replicate the experiments and results described. Authors are strongly encouraged to share any novel reagents that are not commercially available with other researchers. Generic names should be used for all compounds, trade names may be used in parentheses after the generic name. The sources of unusual materials and chemicals, and the manufacturer and model of equipment used should be indicated. Authors are also encouraged to consult and follow any reporting guidelines relevant to their specific research design, in particular:

Research Ethics

A statement of ethics committee or institutional review board approval of the studies being reported must be made in the Materials and Methods section and the relevant reference numbers and dates must be given.
When reporting experiments on human subjects, indicate whether procedures were in accordance with the ethical standards of the institutional, regional, or national committee on human experimentation, and with the Declaration of Helsinki (as revised in Brazil 2013), available at Patients’ rights to privacy must not be infringed without informed consent. Do not use patients’ names, initials, hospital numbers or any other identifying information in any part of a manuscript (text or figures), unless the information is essential for scientific reasons and the patient (or their parent or guardian) has given written informed consent for publication.
When reporting experiments on animals, indicate whether the institution’s or a national research council’s guide for, or any national law on, the care and use of laboratory animals was followed. We ask all authors to carefully consider the ethical use of animals in their research.

Conflicts of interest statement

Authors are responsible for disclosing all financial and personal relationships between themselves (or close relatives) and other parties (such as commercial companies) that might bias their work. A conflict of interest statement must be included in every manuscript and it must detail any conflicts that exist for each author, or declare the absence of conflict for each author. Potential conflicts include, but are not limited to: employment, membership upon an Advisory Board, receiving grants to cover research, travel or accommodation, the ownership of shares, share options, stocks or bonds, being named on a related patent, being loaned or given equipment, etc.


References should be cited by bracketed numbers and listed at the end of the paper in the order in which they appear in the text. All references must be complete and accurate. For articles with more than 6 authors, only the first 3 authors should be listed, followed by et al. For articles with 6 authors or fewer, all names should be listed. Where possible the DOI for the reference should be included at the end of the reference. Online citations should include date of access. Use Medline abbreviations for journal names, which can be found at: If necessary, cite unpublished or personal work in the text but do not include it in the reference list. References should be listed in the following style:

  • Rosenberg S, Aebersold P, Cornetta K, et al. Gene transfer into humans - immunotherapy of patients with advanced melanoma, using TIL modified by retroviral gene transduction. N Engl J Med 1990; 323: 570-578.DOI: 10.1002/nej.850
  • Kemshead J, Patel K. N-myc - Its place as a diagnostic and prognostic indicator in neuroblastoma. In Genes and Cancer, Sikora K, Carney D (eds). John Wiley & Sons: Chichester, 1990; 145-157.
  • Lowenstein PR, Enquist LW (eds). Transfer in Neuroscience: Towards Gene Therapy of Neurological Disorders. John Wiley & Sons: New York, 1996.

*The Digital Object Identifier (DOI) is an identification system for intellectual property in the digital environment. Developed by the International DOI Foundation on behalf of the publishing industry, its goals are to provide a framework for managing intellectual content, link customers with publishers, facilitate electronic commerce, and enable automated copyright management.

Tables should be self-contained and complement, but not duplicate, information contained in the text. Number tables consecutively in the text in Arabic numerals. Type tables on a separate page with the legend above. Legends should be concise but comprehensive – the table, legend and footnotes must be understandable without reference to the text.

Submit each figure as a separate file except compound figures e.g. 1a, 1b, 1c etc, which should be supplied as a single file. Supply artwork at the intended size for printing. Use hatchings, not tints.

Preparation of Electronic Figures for Publication: Although low quality images are adequate for review purposes, publication requires high quality images to prevent the final product being blurred or fuzzy. Submit EPS (line art) or TIFF (halftone/photographs) files only. MS PowerPoint and Word Graphics are unsuitable for printed pictures. Do not use pixel-oriented programmes. Scans (TIFF only) should have a resolution of 300 dpi (halftone) or 600 to 1200 dpi (line drawings) in relation to the reproduction size (see below). EPS files should be saved with fonts embedded (and with a TIFF preview if possible). For scanned images, the scanning resolution (at final image size) should be as follows to ensure good reproduction: line art: >600 dpi; half-tones (including gel photographs): >300 dpi; figures containing both halftone and line images: >600 dpi. More advice on figures can be found at Wiley’s guidelines for preparation of figures:

Supporting Information
Supporting information is not essential to the article but provides greater depth and background and may include tables, figures, videos, datasets, etc. This material can be submitted with your manuscript, and will appear online, without editing or typesetting. Guidelines on how to prepare this material and which formats and files sizes are acceptable can be found at:

Please note that the provision of supporting information is not encouraged as a general rule. It will be assessed critically by reviewers and editors and will only be accepted if it is essential.


Two Word-files need to be included upon submission: A title page file and a main text file that includes all parts of the text, including tables and figure legends but excluding figures which should be supplied separately.

The main text file should be prepared using Microsoft Word using 1.5 line spacing. All pages should be numbered consecutively in the top right-hand corner, beginning with the first page of the main text file.

Each figure should be supplied as a separate file, with the figure number incorporated in the file name. For submission, low-resolution figures saved as .jpg or .bmp files should be uploaded, for ease of transmission during the review process. Upon acceptance of the article, high-resolution figures (at least 300 d.p.i.) saved as .eps or .tif files will be required.


Accepted papers will be passed to Wiley’s production team for publication. The author identified as the formal corresponding author for the paper will receive an email prompting them to login into Wiley’s Author Services, where via the Wiley Author Licensing Service (WALS) they will be asked to complete an electronic license agreement on behalf of all authors on the paper. More details on the copyright and licencing options for the journal appear below.

Wiley’s Author Services

Tracking your paper’s progress Author Services also enables authors to track their article through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production. The corresponding author will receive a unique link that enables them to register and have their article automatically added to the system. Visit for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

Accepted Articles

The journal offers Wiley’s Accepted Articles service for all manuscripts. This service ensures that accepted ‘in press’ manuscripts are published online very soon after acceptance, prior to copy-editing or typesetting. Accepted Articles are published online a few days after final acceptance, appear in PDF format only, are given a Digital Object Identifier (DOI), which allows them to be cited and tracked, and are indexed by PubMed. After print publication, the DOI remains valid and can continue to be used to cite and access the article.

The Accepted Articles service has been designed to ensure the earliest possible circulation of research papers after acceptance. Given that copyright licensing is a condition of publication, a completed copyright form is required before a manuscript can be processed as an Accepted Article.

Accepted articles will be indexed by PubMed; therefore the submitting author must carefully check the names and affiliations of all authors provided in the cover page of the manuscript, as it will not be possible to alter these once a paper is made available online in Accepted Article format. Subsequently the final copyedited and proofed articles will appear in an issue on Wiley Online Library; the link to the article in PubMed will automatically be updated.


Once the paper has been typeset the corresponding author will receive an e-mail alert containing instructions on how to provide proof corrections to the article. It is therefore essential that a working e-mail address is provided for the corresponding author.

Early View

The journal offers rapid speed to publication via Wiley’s Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. Early View articles are given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before allocation to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article. More information about DOIs can be found at


A PDF reprint of the article will be supplied free of charge to the corresponding author. Additional printed offprints may be ordered online for a fee. Please click on the following link and fill in the necessary details and ensure that you type information in all of the required fields: If you have queries about offprints please e-mail:

Author Marketing Toolkit

The Wiley Author Marketing Toolkit provide authors with support on how to use social media, publicity, conferences, multimedia, email and the web to promote their article.


Accepted papers will be passed to Wiley’s production team for publication. The author identified as the formal corresponding author for the paper will receive an email prompting them to login into Wiley’s Author Services, where via the Wiley Author Licensing Service (WALS) they will be asked to complete an electronic license agreement on behalf of all authors on the paper.

Authors may choose to publish under the terms of the journal’s standard copyright transfer agreement (CTA), or under open access terms made available via Wiley OnlineOpen.

Standard Copyright Transfer Agreement: FAQs about the terms and conditions of the standard CTA in place for the journal, including standard terms regarding archiving of the accepted version of the paper, are available at: Copyright Terms and Conditions FAQs.

Note that in signing the journal’s licence agreement authors agree that consent to reproduce figures from another source has been obtained.

OnlineOpen – Wiley’s Open Access Option: OnlineOpen is available to authors of articles who wish to make their article freely available to all on Wiley Online Library under a Creative Commons license. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made open access. Authors of OnlineOpen articles are permitted to post the final, published PDF of their article on their personal website, and in an institutional repository or other free public server immediately after publication. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

OnlineOpen licenses. Authors choosing OnlineOpen retain copyright in their article and have a choice of publishing under the following Creative Commons License terms: Creative Commons Attribution License (CC BY); Creative Commons Attribution Non-Commercial License (CC BY NC); Creative Commons Attribution Non-Commercial-NoDerivs License (CC BY NC ND). To preview the terms and conditions of these open access agreements please visit the Copyright Terms and Conditions FAQs.

Funder Open Access and Self-Archiving Compliance: Please click here for more information on Wiley’s compliance with specific Funder Open Access and Self Archiving Policies, and click here for more detailed information specifically about Self-Archiving definitions and policies.


Authority and Responsibility
The intellectual content of the paper is the responsibility of the authors. The Editors and the Publisher accept no responsibility for opinions and statements of authors. While every effort will be made by the Editor and Publisher to avoid inaccurate and misleading data, they accept no liability whatsoever for the consequences of wrong information. The authors agree to keep the Editors and Publisher fully and effectually indemnified against any liability or claims that may arise out of the publication of inaccurate and/or misleading data.

Committee on Publication Ethics. The journal is a member of, and subscribes to the principles of the Committee on Publication Ethics (COPE).

Author Guidelines updated 27 May 2015