Chemistry - A European Journal
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor: Neville Compton, Deputy Editors: Anne Deveson, Elisabeth Roedern
Impact Factor: 5.731
ISI Journal Citation Reports © Ranking: 2014: 22/157 (Chemistry Multidisciplinary)
Online ISSN: 1521-3765
Associated Title(s): Angewandte Chemie International Edition, Chemistry – An Asian Journal, ChemistryOpen, ChemistrySelect, ChemBioChem, ChemCatChem, ChemElectroChem, ChemMedChem, ChemPhysChem, ChemPlusChem, ChemSusChem, European Journal of Inorganic Chemistry, European Journal of Organic Chemistry
Recently Published Articles
- Direct Metal-Free Entry to Aminocyclobutenes or Aminocyclobutenols from Ynamides: Synthetic Applications
Prof. Dr. Benito Alcaide, Prof. Dr. Pedro Almendros and Carlos Lázaro-Milla
Version of Record online: 27 MAY 2016 | DOI: 10.1002/chem.201601044
Bis(triflyl)aminocyclobutenes, 2-amino-3-(triflyl)cyclobut-2-enols, or aminocyclobutenyl ethers from ynamides are prepared by a regioselective [2+2] cycloaddition or a cyclization/hydroxylation (hydroalkoxylation) sequence. These functionalized aminocyclobutenes are coverted into α-amino-β,γ-unsaturated ketones or 3-(triflyl)buta-1,3-dien-2-amines through 4 π-electrocyclic ring-opening reactions.
- Aniline-Promoted Cyclization–Replacement Cascade Reactions of 2-Hydroxycinnamaldehydes with Various Carbonic Nucleophiles through In Situ Formed N,O-Acetals
Chenguang Yu, He Huang, Xiangmin Li, Prof. Dr. Yueteng Zhang, Hao Li and Prof. Dr. Wei Wang
Version of Record online: 27 MAY 2016 | DOI: 10.1002/chem.201601112
Cascade catalysis: New reactivity of N,O-acetals has been harnessed in an aminocatalytic cascade fashion for the efficient synthesis of 2-substituted 2H-chromenes.
- Manganese-Mediated C−H Alkylation of Unbiased Arenes Using Alkylboronic Acids
Dr. Susana Castro, Juan J. Fernández, Prof. Dr. Francisco J. Fañanás, Dr. Rubén Vicente and Prof. Félix Rodríguez
Version of Record online: 27 MAY 2016 | DOI: 10.1002/chem.201601482
The alkylation of simple arenes, usually performed by the traditional Friedel–Crafts reaction, may also be achieved by an alternative and competitive method involving alkylboronic acids as alkylating reagents and a manganese(III) salt as promoter (see scheme).
- The Origin of Anti-Markovnikov Regioselectivity in Alkene Hydroamination Reactions Catalyzed by [Rh(DPEphos)]+
Almudena Couce-Rios, Prof. Dr. Agustí Lledós and Dr. Gregori Ujaque
Version of Record online: 25 MAY 2016 | DOI: 10.1002/chem.201504645
Crossing paths: The reaction mechanism for intermolecular hydroamination of alkenes catalyzed by [Rh(DPEphos)]+ complex was analyzed by means of DFT calculations (see scheme). Hydroamination (alkene vs. amine activation routes) as well as oxidative amination pathways were analyzed.
- Supramolecular Gels by Design: Towards the Development of Topical Gels for Self-Delivery Application
Rumana Parveen and Prof. Dr. Parthasarathi Dastidar
Version of Record online: 25 MAY 2016 | DOI: 10.1002/chem.201600105
Anti-inflammatory gel: A supramolecular synthon approach has been adopted to generate a series of simple organic salts of ibuprofen. These are capable of forming topical gels, which proved to be useful both in vitro and in vivo to treat skin inflammation.