Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 28

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, Zeitschrift für Chemie

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Notice to Authors: NEW

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Abstracts now required for Communications

To improve the discoverability of Communications, we ask authors to supply an abstract as the first paragraph from now on. In this abstract, the motivation for the work, the methods applied, the results, and the conclusions drawn should be presented (maximum 1000 characters).

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Nazario Martín

“My biggest motivation is the best is yet to come! If I were not a scientist, I would be a writer or actor—or maybe a bishop ...” This and more about Nazario Martín can be found on page 7116.

Angew. Chem. Int. Ed.2014, 53, No. 28, 7116-7117

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July 03, 2014

Angewandte Chemie 28/2014: The Sweet Smell of Success

Angewandte Chemie 28/2014: The Sweet Smell of SuccessIn this issue, T. Hofmann et al. review the chemistry of smell. What are nature's chemical signatures in human olfaction and what are the perspectives for future food biotechnology? The Highlight deals with electrosynthetic methods for complex molecular syntheses (S. R. Waldvogel and B. Janza).

In the Communications section, M. Akita et al. present a facile synthesis of α-trifluoromethylated ketones from aromatic alkenes by means of photoredox catalysis (see picture). B. Liu et al. used a polyelectrolyte-based polyprodrug for photodynamic and chemotherapy with on-demand drug release. S. Zacchini et al. describe a hydride migration from a triangular face to a tetrahedral cavity in tetranuclear iron carbonyl clusters.

Browse issue 28/2014 now.

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Press Release

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Cholera: Fighting Fire with Fire

Binding at five sites: effective cholera inhibitor based on cholera toxins

Cholera: Fighting Fire with Fire - Binding at five sites: effective cholera inhibitor based on cholera toxins

Cholera against cholera: a novel inhibitor prevents the cholera toxin from binding to carbohydrates found on the surface of intestinal cells. An international team of researchers has described their elegant concept in the journal Angewandte Chemie: The protein scaffold of the inhibitor is based on an inactive cholera toxin. It is equipped with five sugar moieties to act as ligands. The inhibitor’s size and number of binding sites are both perfectly matched to the cholera toxin bearing five binding sites.

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alkynes · asymmetric catalysis · asymmetric synthesis · C-H activation · copper · cycloaddition · density functional calculations · electrochemistry · fluorescence · gold · heterocycles · heterogeneous catalysis · homogeneous catalysis · magnetic properties · nanoparticles · nanostructures · natural products · NMR spectroscopy · organocatalysis · oxidation · palladium · peptides · polymers · rhodium · ruthenium · self-assembly · structure elucidation · supramolecular chemistry · synthetic methods · total synthesis