Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 44

Editor: Neville Compton; Editor Emeritus: Peter Gölitz

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

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Yasujiro Murata

Yasujiro Murata

“If I were a car I would be a red Porsche 911. If I could be anyone for a day, I would be the conductor of an orchestra ...” This and more about Yasujiro Murata can be found on page 13562.

Angew. Chem. Int. Ed.2017, 56, No. 44, 13562–13562.

Editorial

Jean-Christophe Leroux
Drug Delivery: Too Much Complexity, Not Enough Reproducibility?

Drug Delivery: Too Much Complexity, Not Enough Reproducibility?

“… Drug-delivery research is experiencing a major expansion, however the upsurge in published reports does not correlate with therapeutic advances. Reporting complex systems seems to have prevailed over the desire to treat a disease effectively with a robust and safe formulation. Another important issue is the lack of reproducibility of published findings …” Read more in the Editorial by Jean-Christophe Leroux.

Angew. Chem. Int. Ed. https://doi.org/10.1002/anie.201709002

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October 19, 2017

Angewandte Chemie 44/2017: Perfect Arrangement

Angewandte Chemie 44/2017: Perfect ArrangementIn this issue, C. M. Niemeyer et al. review cascades in compartments for machine-assisted biotechnology. How can molecular scaffolds with small cross-linkers, proteins, nucleic acids, colloids, and patterned surfaces be used to arrange the catalytic units? The Highlights deal with enantioselective [2,3]-sigmatropic rearrangements (K. J. Kock and R. M. Koenigs) and autocatalytic N-methylation in biosynthesis (H. Aldemir and T. A. M. Gulder).

In the Communications section, B. H. Meier et al. describe correlation-time analysis by NMR spectroscopy (see picture). R. E. Winpenny et al. present a family of heterometallic titanium(IV)–metal(III) rings with structure control through templates. X. Qu et al. used manganese dioxide nanozymes as responsive shells for individual living-cell encapsulation.

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Fluorine-Containing Molecules from Cell Cultures

Living cells produce fluorinated metabolites and bioplastics

Fluorine-Containing Molecules from Cell Cultures - Living cells produce fluorinated metabolites and bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide. As reported in the journal Angewandte Chemie, the diketide could then be used as a monomer for the in vivo production of fluorinated bioplastics.

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