Guest-Adaptable and Water-Stable Peptide-Based Porous Materials by Imidazolate Side Chain Control
Dr. Alexandros P. Katsoulidis, Dr. Kyo Sung Park, Dr. Dmytro Antypov, Dr. Carlos Martí-Gastaldo, Dr. Gary J. Miller, Dr. John E. Warren, Dr. Craig M. Robertson, Dr. Frédéric Blanc, Dr. George R. Darling, Dr. Neil G. Berry, Dr. John A. Purton, Dr. Dave J. Adams and Prof. Matthew J. Rosseinsky
Article first published online: 2 DEC 2013 | DOI: 10.1002/anie.201307074
A peptide-based porous framework (ZnCar⋅DMF), which is formed by the assembly of Zn with carnosine, exhibits permanent microporosity and has pores of chiral shape. Zn–imidazolate bonding to the histidine side chain affords the chemical stability of the framework in water, and the His-β-Ala main chain provides flexibility while conferring structural adaptability on the framework in the presence of different guest molecules.