Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 6

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

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Microscopic Submarines for Your Stomach - Micromotors neutralize gastric acid and release drugs depending on pH

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Microscopic Submarines for Your Stomach

Micromotors neutralize gastric acid and release drugs depending on pH.
Tiny “submarines” that speed independently through the stomach, use gastric acid for fuel (while rapidly neutralizing it), and release their cargo precisely at the desired pH: Though it may sound like science fiction, this is a new method for treating stomach diseases with acid-sensitive drugs introduced by scientists in the journal Angewandte Chemie. The technique is based on proton-driven micromotors with a pH-dependent polymer coating that can be loaded with drugs.

Read more.

No.Press ReleaseOriginal Communication

January 23, 2017

Microscopic Submarines for Your Stomach
Micromotors neutralize gastric acid and release drugs depending on pH
(PDF)

Micromotors Spontaneously Neutralize Gastric Acid for pH-Responsive Payload Release

Joseph Wang, University of California, San Diego (USA)


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