Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 23

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

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Nanosubmarine with Self-Destroying Activity - Self-destroyed redox-sensitive stomatocyte nanomotor delivers and releases drugs for cells

Latest News

Nanosubmarine with Self-Destroying Activity

Self-destroyed redox-sensitive stomatocyte nanomotor delivers and releases drugs for cells.
Autonomous targeting and release of drugs at their site of action are desired features of nanomedical systems. Now, a team of Dutch scientists has designed a nanomotor that has these functions: An antitumor drug encapsulated in self-propelled, self-assembled stomatocytes is carried across the cellular membrane and released inside the cell upon a chemical redox signal that disassembles the vesicle membrane. This deliver and unpack nanomedicinal system is introduced in the journal Angewandte Chemie.

Read more.

DatePress ReleaseOriginal Communication

May 29, 2017

Nanosubmarine with Self-Destroying Activity
Self-destroyed redox-sensitive stomatocyte nanomotor delivers and releases drugs for cells
(PDF)

Redox-Sensitive Stomatocyte Nanomotors: Destruction and Drug Release in the Presence of Glutathione

Daniela A. Wilson, Radboud Universiteit Nijmegen (The Netherlands)


May 22, 2017

Micro Delivery Service for Fertilizers
Tailored microgel containers for plant health
(PDF)

Biofunctional Microgel-Based Fertilizers for Controlled Foliar Delivery of Nutrients to Plants

Andrij Pich, DWI / RWTH Aachen (Germany)


May 5, 2017

Poultry Feed with Arsenic More Problematic than Assumed?
New methylated phenylarsenical metabolites identified in chicken livers
(PDF)

Methylated Phenylarsenical Metabolites Discovered in Chicken Liver

X. Chris Le, University of Alberta (Canada)


May 4, 2017

Deadly Nanoparcel for Cancer Cells
Free-radical-generating hybrid nanomaterial for the oxidative destruction of hypoxic cancer cells
(PDF)

A Hybrid Nanomaterial for the Controlled Generation of Free Radicals and Oxidative Destruction of Hypoxic Cancer Cells

Younan Xia, Georgia Institute of Technology (USA)


April 27, 2017

Mushrooms Get Defensive
One single enzyme induces the chemical defense of a mushroom against larvae
(PDF)

Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase

Dirk Hoffmeister, Friedrich-Schiller-Universität Jena (Germany)


April 11, 2017

All in One Against CO2
Elemental Boron is an effective photothermocatalyst for the conversion of carbon dioxide
(PDF)

Elemental Boron for Efficient Carbon Dioxide Reduction under Light Irradiation

Jinhua Ye, National Institute for Materials Science (Japan)


April 3, 2017

Restoration Based on Chemistry
Large-area chemical imaging reveals original paint layers on Ghent altarpiece
(PDF)

Large-Area Elemental Imaging Reveals Van Eyck's Original Paint Layers on the Ghent Altarpiece (1432), Rescoping Its Conservation Treatment

Geert Van der Snickt, Universiteit Antwerp (Belgium)


March 30, 2017

What Happens in the Living Cell?
"Molecular activity painting" to control and monitor switch-like, light-controlled perturbations inside cells
(PDF)

"Molecular-Activity Painting": Switch-like, Light-Controlled Perturbations inside Living Cells

Leif Dehmelt, TU Dortmund / MPI Mol. Physiol. (Germany)


March 27, 2017

Mobile Gold Fingers
Travelling-wave ion mobility mass spectrometry elucidates structures of gold fingers
(PDF)

Diversity in Gold Finger Structure Elucidated by Traveling-Wave Ion Mobility Mass Spectrometry

Nicholas P. Farrell, Virginia Commonwealth University (USA)


March 24, 2017

Lighting up Antibiotic Resistance
A fluorogenic probe can detect the activity of multidrug-resistant pathogens in an assay system
(PDF)

Detection of Carbapenemase-Producing Organisms with a Carbapenem-Based Fluorogenic Probe

Hexin Xie, East China University of Science and Technology (China)


March 23, 2017

Evolutionary Advantage of the Common Periwinkle
Adding one heavy-metal-binding domain in a cysteine-rich protein may be one of the sea snail’s adaptations to metal stress
(PDF)

Structural Adaptation of a Protein to Increased Metal Stress: NMR Structure of a Marine Snail Metallothionein with an Additional Domain

Oliver Zerbe, Universität Zürich (Switzerland)


March 21, 2017

Better Learning through Zinc?
Zinc regulates the storage and release of neurotransmitters
(PDF)

Zinc Regulates Chemical-Transmitter Storage in Nanometer Vesicles and Exocytosis Dynamics as Measured by Amperometry

Andrew G. Ewing, Chalmers University of Technology (Sweden)


February 17, 2017

In-Mouse Catalysis
Organ-targeted metal-complex catalysis within living biological systems
(PDF)

In Vivo Gold Complex Catalysis within Live Mice

Katsunori Tanaka, RIKEN (Japan)


February 15, 2017

Bursting Pods
Molecular switch drives powerful movement by opposing twisting helices
(PDF)

High-Power Actuation from Molecular Photoswitches in Enantiomerically Paired Soft Springs

Nathalie Katsonis, University of Twente (Netherlands)


February 9, 2017

Direct Radiolabeling of Nanomaterials
Directly radiolabeled nanographene materials without chelators are suitable for bioimaging applications
(PDF)

Chelator-Free Radiolabeling of Nanographene: Breaking the Stereotype of Chelation

Weibo Cai, University of Wisconsin Madison (USA)


February 6, 2017

Pharmaceuticals from a Coal Mine?
Novel microbial geldanamycin derivatives and cyclopentenone ansamycins from an abandoned coal min
(PDF)

Mccrearamycins A–D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe

Jon S. Thorson, University of Kentucky (USA)


January 30, 2017

Nature-Based Sunscreens
Boosting the solar protection factor with rationally designed, nature-inspired sunscreens
(PDF)

Rational Design and Synthesis of Efficient Sunscreens To Boost the Solar Protection Factor

Diego Sampedro, Universidad de La Rioja (Spain)


January 23, 2017

Microscopic Submarines for Your Stomach
Micromotors neutralize gastric acid and release drugs depending on pH
(PDF)

Micromotors Spontaneously Neutralize Gastric Acid for pH-Responsive Payload Release

Joseph Wang, University of California, San Diego (USA)


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