Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 50

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

Press Room

Have a look at our recent Press Releases. Registered Members of the Press may also access the relevant original communication as well as annotated tables of contents.

Please address any questions to the Editorial Office or directly to the authors, whose addresses are mentioned in the articles. Please let us know your comments on this service!

Did we overlook your article in our media coverage page? Let us know!

As of 2005, please note that the numbering of the press releases does not necessarily match the numbering of the issues.

Archive: 2006, 2005, 2004, 2003, 2002, 2001

To read the PDF supplied you may need
an additional program such as Acrobat Reader.

Table of
Press ReleaseOriginal Communication


Converting Nitrogen to a More Useful Form
Nitrogen fixation: Hafnium complex couples atmospheric nitrogen with carbon dioxide

Nitrogen–Carbon Bond Formation from N2 and CO2 Promoted by a Hafnocene Dinitrogen Complex Gives Access to a Substituted Hydrazine

Paul J. Chirik, Cornell University, Ithaca (USA)


How Does Aspirin Crystallize?
Two different crystalline forms of aspirin in intergrown domains

On the Polymorphism of Aspirin

Roland Boese, Universität Duisburg-Essen (Germany)


Molecular Solomon’s Knot
Self-organization leads to intertwined molecular rings

A Molecular Solomon Link

J. Fraser Stoddart, University of California, Los Angeles (USA)


Hairpins for Switches
Artificial RNA ligands differentiate between on and off states of riboswitches

RNA Ligands That Distinguish Metabolite-Induced Conformations in the TPP Riboswitch

Michael Famulok, Universität Bonn (Germany)


Weighty Viruses
Weight determination of individual viruses with a miniature ion trap

Microscopy-Based Mass Measurement of a Single Whole Virus in a Cylindrical Ion Trap

Huan-Cheng Chang, Academia Sinica, Taipei (Taiwan)


Just Dive In
Highly sensitive but easy to handle: test strips for the rapid detection of cocaine

A Simple and Sensitive "Dip-Stick" Test in Serum Based on Lateral Flow Separation of Aptamer-Linked Nanostructures

Yi Lu, University of Illinois at Urbana-Champaign, Urbana (USA)


Critical Pairing
Origin of life: the search for the first genetic material

Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements / Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4-Disubstituted 5-Aminopyrimidines as Recognition Elements

Ramanarayanan Krishnamurthy, The Scripps Research Institute, La Jolla, CA (USA)


Please Exhale
Quick and easy breath analysis

Rapid In Vivo Fingerprinting of Nonvolatile Compounds in Breath by Extractive Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry

Renato Zenobi, ETH Zürich (Switzerland)


Platinum Cages
Liposomes as blueprints for hollow platinum nanospheres

Synthesis of Platinum Nanocages by Using Liposomes Containing Photocatalyst Molecules

John A. Shelnutt, University of Georgia, Athens (USA)


Twisted Molecule
Large and folded like a protein—but completely synthetic

Proteomorphous Objects from Abiotic Backbones

Ivan Huc, Institut Européen de Chimie et Biologie, Pessac (France)


The Smell of Iron
“Metallic” odor of iron, iron-containing water, and blood derives from the decomposition of skin oil

The Two Odors of Iron when Touched or Pickled: (Skin) Carbonyl Compounds and Organophosphines

Dietmar Glindemann, Virginia Polytechnic Institute and State University, Blacksburg (USA)


Killing Resistant Germs
Total synthesis successful: Platensimycin, a new antibiotic

Total Synthesis of Platensimycin

K. C. Nicolaou, The Scripps Research Institute, La Jolla (USA)


Electromagnetic Miniatures
Simultaneous production of microchannels with parallel, electrically conducting metal wires

Cofabrication of Electromagnets and Microfluidic Systems in Poly(dimethylsiloxane)

George M. Whitesides, Harvard University, Cambridge (USA)


Built-in Blocker
Drug and antidote in the same molecule: New blood-clotting inhibitor that can be switched off by irradiation

An Anticoagulant with Light-Triggered Antidote Activity

Alexander Heckel, Universität Bonn (Germany)


Molecules Dress for Success
Suitanes: mechanically interlocked molecules


J. Fraser Stoddart, University of California, Los Angeles (USA)


Form Determines Function
Nerve Regeneration: cyclopeptides imitate the structure and effect of the HNK-1 carbohydrate

Glycomimetic Cyclic Peptides Stimulate Neurite Outgrowth

Norbert Sewald, Universität Bielefeld (Germany)


From Bubbles to Capsules
Making silicon dioxide nanocapsules by frothing polymers with supercritical carbon dioxide

Nanoscale Silica Capsules Ordered on a Substrate: Oxidation of Nanocellular Thin Films of Poly(styrene-b-dimethylsiloxane)

Hideaki Yokoyama, National Institute of Advanced Industrial Science and Technology, Tsukuba (Japan)


Switchable Lotus Effect
Material with light-switchable super-water-repellent properties

Photoinduced Reversible Formation of Microfibrils on a Photochromic Diarylethene Microcrystalline Surface

Kingo Uchida, Ryukoku University, Otsu (Japan)


Unusual Rods
Get thicker when stretched, thinner when compressed: simulations identify auxetic molecules

Auxetics at the Molecular Level: A Negative Poisson's Ratio in Molecular Rods

Shmaryahu Hoz, Bar-Ilan University, Ramat-Gan (Israel)


Anthrax Detector Developed
Monoclonal antibody recognizes a specific sugar on the surface of anthrax bacteria spores

Anti-Carbohydrate Antibodies for the Detection of Anthrax Spores

Peter Seeberger, ETH Zürich (Switzerland)


Encoded Metallic Nanowires Reveal Bioweapons
Striped nanowires of silver and gold for parallel detection of various pathogens

Metallic Striped Nanowires as Multiplexed Immunoassay Platforms for Pathogen Detection

Jeffrey B.-H. Tok, Lawrence Livermore National Laboratory (USA)


Well-Packaged Drugs
Metal–organic crystals with large pores store drugs and release them over time

Metal-Organic Frameworks as Efficient Materials for Drug Delivery

Christian Serre, Gérard Férey, Inst. Lavoisier, Versailles (France)


Proteins as Parents
Construction of proteins with new mechanical properties through recombination of protein fragments

Engineering Proteins with Novel Mechanical Properties by Recombination of Protein Fragments

Hongbin Li, University of British Columbia, Vancouver (Canada)


Gluing Cells
Precise sticking of living cells on carriers by microelectrochemical methods

Switching On Cell Adhesion with Microelectrodes

Gunther Wittstock, Carl-von-Ossietzky-Universität Oldenburg (Germany)


Two-Stage Amplifier
Coupling two enzymatic reactions: sensitive detection for immunological ELISA tests

Biocatalytic Evolution of a Biocatalyst Marker: Towards the Ultrasensitive Detection of Immunocomplexes and DNA Analysis

Itamar Willner, The Hebrew University of Jerusalem (Israel)


Precious metal gets picky
Gold nanoparticles adhere to only certain faces of crystals of the amino acid cystine

Anisotropic Decoration of Gold Nanoparticles onto Specific Crystal Faces of Organic Single Crystals

Kazuki Sada, Kyushu University, Fukuoka (Japan)


Remote Control
Microcapsules enter cells and an external flash of light triggers release of their contents

Laser-Induced Release of Encapsulated Materials inside Living Cells

Andre G. Skirtach, Max-Planck-Institut für Kolloid- und Grenzflächenforschung, Golm/Potsdam (Germany)


Field Games
Electric field provides stimulus: chemical system responds by forming liquid crystals

Electric-Field Modulation of Phase-Transition Temperature in Constitutional Dynamic Liquid Crystals

Jean-Marie Lehn, Institut de Science et d�Ingénierie Supramoléculaires, Strasbourg (France)


Chip Indicates Mutation
DNA chips for the rapid and reliable identification of point mutations

SNP Genotyping by Using Photochemical Ligation

Kenzo Fujimoto, Japan Advanced Institute of Science and Technology


Hot off the Press
Universal ink for microcontact printing

Universal Ink for Microcontact Printing

Dirk Burdinski, Philips Research, Eindhoven (The Netherlands)


Renewable Raw Materials
Glycerol produced in the fermentation of sugar is used in the synthesis of hydrocarbons

Glycerol as a Source for Fuels and Chemicals by Low-Temperature Catalytic Processing

James A. Dumesic, University of Wisconsin, Madison (USA)


Your Monitor as an Analytical Tool
Detection of amines, CO, and NOx by computer monitor and web camera

Chemical Sensing with Familiar Devices

Ingemar Lundström, Linköpings Universitet (Sweden)


Molecule Within a Molecule
Macrocyclic cyclophanes form tubular structures that can enclose smaller molecules

Cyclophanes Within Cyclophanes: The Synthesis of a Pyromellitic Diimide-Based Macrocycle as a Structural Unit in a Molecular Tube and Its Inclusion Phenomena

Teruo Shinmyozu, Kyushu University, Kukuoka (Japan)


Making Cancer Cells Visible
Tumor proteases change the magnetic properties of nanoparticles

Proteolytic Actuation of Nanoparticle Self-Assembly

Sangeeta N. Bhatia, Massachusetts Institute of Technology, Cambridge (USA)


DNA Taxi
Photosensitive gold nanoparticles can electrostatically bind DNA and then release it under UV light

Light-Regulated Release of DNA and its Delivery to Nuclei by Means of Photolabile Gold Nanoparticles

Vincent M. Rotello, University of Massachusetts, Amherst (USA)


Molecular Switches
Optoelectronic components based on a dye-sensitized TiO2 solar cell

TiO2-Based Light-Driven XOR/INH Logic Gates

Koiti Araki, Universidade de São Paulo (Brazil)


Chemical Storage Units
Oscillating chemical reactions can retain patterns produced by light

A Reaction–Diffusion Memory Device

Irving R. Epstein, Brandeis University, Waltham, MA (USA)


Good Memory
On the way to plastic electronics: polymer-based dynamic random access memory (DRAM)

A Dynamic Random Access Memory (DRAM) Based on a Conjugated Copolymer Containing Electron-Donor and -Acceptor Moieties

En-Tang Kang, National University of Singapore (Singapore)


Hula-Hoop Nanotechnique
Periodic nanostructures made of gold nanoparticles and long DNA strands with repeated sequences

DNA Polymerization on Gold Nanoparticles through Rolling Circle Amplification: Towards Novel Scaffolds for Three-Dimensional Periodic Nanoassemblies

Yingfu Li, McMaster University, Hamilton (Canada)


Footprints of a Blood Cell
Determination of blood types with a microbalance and embossed plastic surfaces

Biomimetic ABO Blood-Group Typing

Franz L. Dickert, Universität Wien (Austria)


Starving Out Malaria Parasites
New class of selective inhibitors paralyze essential plasmodium enzymes

Starving the Malaria Parasite: Inhibitors Active against the Aspartic Proteases Plasmepsins I, II, and IV

François Diederich, ETH Zürich (Switzerland)


Tracking Genetic Variation
“Electronic” DNA sequencing: Changes in molecular charge act as signal

DNA Sequencing Based on Intrinsic Molecular Charges

Yuji Miyahara, National Institute for Materials Science, Tsukuba (Japan)


Hard Shell – Soft Core
Polymeric microspheres have a shell whose density is dependent on the temperature

Temperature-Sensitive Core–Shell Microgel Particles with Dense Shell

Walter Richtering, RWTH Aachen (Germany)


Organic Hydrogen Storage
Microporous polymers made of fused hydrocarbon rings can adsorb hydrogen

Towards Polymer-based Hydrogen Storage Materials: Engineering Ultramicroporous Cavities Within Polymers of Intrinsic Microporosity

Neil B. McKeown, Cardiff University (UK)


Computing with Enzymes
Coupled enzyme systems are models for simple circuits

Elementary Arithmetic Operations by Enzymes: A Model for Metabolic Pathway Based Computing

Itamar Willner, The Hebrew University of Jerusalem (Israel)


Telltale Swelling
Soft microlenses as biosensors: change in focal distance signals presence of analyte molecules

Label-Free Biosensing with Hydrogel Microlenses

L. Andrew Lyon, Georgia Institute of Technology, Atlanta (USA)


Searching for Traces
Detection of the tiniest quantities of proteins by means of aptamers and PCR

Ultrasensitive Detection of Proteins by Amplification of Affinity Aptamers

Chris Le, University of Alberta, Edmonton (Canada)


In Good Shape
Metal atom dictates the structure: new concept for the construction of enzyme inhibitors

Ruthenium Half-Sandwich Complexes Bound to Protein Kinase Pim-1

Eric Meggers, University of Pennsylvania, Philadelphia (USA)


A molecule that changes its conformation when irradiated with light: prototype of a light-controlled foldamer

Prototype of a Photoswitchable Foldamer

Stefan Hecht, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr (Germany)


Coal Liquefaction
Hydration in the presence of borane or iodine catalysts smoothes the way for the liquefaction of semianthracite coal

The First Liquefaction of High-Grade Bituminous Coals by Preceding Hydrogenation with Homogeneous Borane or Iodine Catalysts

Matthias W. Haenel, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr (Germany)





Fixing by Filtration
New testing strips for detecting heavy metals

Test Strips for Heavy-Metal Ions Fabricated from Nanosized Dye Compounds

Toshishige M. Suzuki, AIST Tohoku (Japan)