Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 44

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

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Beer's Bitter - The absolute configurations of the bitter acids of hops determined

Latest News

Beer's Bitter

The absolute configurations of the bitter acids of hops determined.
During brewing, beer obtains its bitter flavor from the bitter acids that come from hops. In the journal Angewandte Chemie, scientists now report that they have used X-ray crystallography to determine the absolute configurations of these humulones and isohumulones, as well as several of their derivatives.

Read more.

No.Press ReleaseOriginal Communication

51/2012

Beer's Bitter
The absolute configurations of the bitter acids of hops determined
(PDF)

Absolute Configuration of Beer's Bitter Compounds

Werner Kaminsky, University of Washington, Seattle (USA)


50/2012

Inspired by a Breakwater
Highly efficient electrocatalyst for the reduction of oxygen in fuel cells and batteries
(PDF)

A Highly Efficient Electrocatalyst for the Oxygen Reduction Reaction: N-Doped Ketjenblack Incorporated into Fe/Fe3C-Functionalized Melamine Foam

Jaephil Cho, Ulsan National Institute of Science and Technology (Rep. Korea)


49/2012

Lure for Diatoms
Diatom sex pheromone isolated and characterized
(PDF)

Metabolomics Enabeled Structure Elucidation of a Diatom Sex Pheromone

Georg Pohnert, Friedrich-Schiller-Universität Jena (Germany)


48/2012

pH Sensor for Cell Organelles
pH-dependent conformation change controls energy transfer in nanocrystal sensors
(PDF)

Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal-Based Sensors

Moungi G. Bawendi, Massachusetts Institute of Technology, Cambridge (USA)


47/2012

Improved Performance for Solar Cells
Highly efficient p-type dye-sensitized solar cell with cobalt-based electrolyte
(PDF)

Highly Efficient p-Type Dye-Sensitized Solar Cells based on Tris(1,2-diaminoethane)Cobalt(II)/(III) Electrolytes

Udo Bach, Monash University, Clayton (Australia)


46/2012

From Rotting Mushroom to Drug?
Bacterial virulence factor of mushroom soft rot identified
(PDF)

Imaging Mass Spectrometry and Genome Mining Reveal Highly Antifungal Virulence Factor of Mushroom Soft Rot Pathogen

Christian Hertweck, Leibniz Institute for Natural Product Research and Infection, Jena (Germany)


45/2012

Light and Air
Sunlight-driven CO2 fixation
(PDF)

Solar-Driven Incorporation of Carbon Dioxide into α-Amino Ketones

Masahiro Murakami, Kyoto University (Japan)


44/2012

Inverse Fingerprints on Paper
Visualization of Latent Fingermarks by Nanotechnology: Reversed Development on Paper: A Possible Remedy to the Variation in Sweat Composition
(PDF)

Visualization of Latent Fingermarks by Using Nanotechnology for Reversed Development on Paper: A Remedy to the Variation in Sweat Composition

Joseph Almog, Hebrew University of Jerusalem (Israel)


43/2012

Filming bacterial life in multicolor as a new diagnostic and antibiotic discovery tool
Multicolored probes target cell wall synthesis in the arms race with bacteria
(PDF)

In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with Fluorescent D-Amino Acids

Michael S. VanNieuwenhze, Indiana University, Bloomington (USA)


42/2012

Artificial Blood Maker: EPO
First successful total synthesis of Erythropoietin
(PDF)

At Last: Erythropoietin as a Single Glycoform

Samuel J. Danishefsky, Sloan-Kettering Institute for Cancer Research, New York (USA)


41/2012

Live and in Color
Fluorescent pH-sensitive nanoparticles indicate bacterial growth
(PDF)

Fluorescent pH-Sensitive Nanoparticles in an Agarose Matrix for Imaging of Bacterial Growth and Metabolism

Otto S. Wolfbeis, University of Regensburg (Germany)


40/2012

Hybrid Lighting Device
Bacterial photosynthetic reaction center harvests more light thanks to tailored organic antenna
(PDF)

Enhancing the Light Harvesting Capability of a Photosynthetic Reaction Center by a Tailored Molecular Fluorophore

Massimo Trotta, Istituto per i Processi Chimico Fisici Nazionale delle Ricerche, Bari (Italy)


39/2012

Targeted Attack on Tumors
Selective tumor treatment: β-galactosidase releases active agent from prodrugs
(PDF)

The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy

Sébastien Papot, Université de Poitiers (France)


38/2012

Made out of Thin Air
Fixation of CO2 through iridium catalyzed hydrosilylation
(PDF)

Effective Fixation of CO2 by Iridium-Catalyzed Hydrosilylation

Luis A. Oro, Universidad de Zaragoza (Spain)


37/2012

Landscapes of Taste
An electronic tongue for protein analysis
(PDF)

Continuous Evolution Profiles for Electronic-Tongue-Based Analysis

Yanxia Hou, CEA Grenoble (France)


36/2012

New Treatment for Stroke?
Ceria nanoparticles could lessen the damage from ischemic strokes
(PDF)

Ceria Nanoparticles that Protect against Ischemic Stroke

Taeghwan Hyeon, Seoul National University (Korea)


35/2012

Enzymes Dig Channels
Enzymatic etching used to build nano- and microscale surface topologies
(PDF)

Enzymatic Sculpting of Nanoscale and Microscale Surface Topographies

Victor M. Ugaz, Texas A&M University, College Station (USA)


34/2012

Luminescent Ink from Eggs
Fluorescent carbon dots can be made by plasma pyrolysis and used as printer ink
(PDF)

Amphiphilic Egg-Derived Carbon Dots: Rapid Plasma Fabrication, Pyrolysis Process, and Multicolor Printing Patterns

Su Chen, Nanjing University of Technology (China)


33/2012

Direction Selection
New method for template-directed DNA synthesis in the 3’ and 5’ directions
(PDF)

Template-Directed Synthesis in 3′- and 5′-Direction with Reversible

Clemens Richert, Universität Stuttgart (Germany)


32/2012

Glowing Flowers for Ultra-Trace Analysis of TNT
Selective optical TNT detection down to the sub-zeptomole level
(PDF)

Selective Visual Detection of TNT at the Sub-Zeptomole Level

Thalappil Pradeep, Indian Institute of Technology Madras, Chennai (India)


31/2012

Gold Nanoparticles Follow “Genetic Code”
Different sequences of DNA influence morphology of growing gold nanocrystals
(PDF)

Discovery of the DNA "Genetic Code" for Abiological Gold Nanoparticle Morphologies

Yi Lu, University of Illinois at Urbana-Champaign (USA)


30/2012

Dual Role for CO2
Continuous hydrogenation of carbon dioxide to pure formic acid in supercritical CO2
(PDF)

Continuous-Flow Hydrogenation of Carbon Dioxide to Pure Formic Acid using an Integrated scCO2 Process with Immobilized Catalyst and Base

Walter Leitner, RWTH Aachen University (Germany)


29/2012

Glowing Fingerprints
Researchers make latent fingerprints visible with help from electrochemiluminescence
(PDF)

Imaging Latent Fingerprints by Electrochemiluminescence

Bin Su, Zhejiang University, Hangzhou (China)


28/2012

Secret of “Fetid Fluorite” Aired
Elemental fluorine F2 detected for the first time in a natural mineral
(PDF)

Occurrence of Difluorine F2 in Nature—In Situ Proof and Quantification by NMR Spectroscopy

Florian Kraus, Technische Universität München (Germany)


27/2012

Magnetizing Diagnostics
Magnetic Gram staining detects bacteria
(PDF)

A Magnetic Gram Stain for Bacterial Detection

Ralph Weissleder, Massachusetts General Hospital, Boston (USA)


26/2012

CO2 as a Carbon Source?
Homogeneous catalysis: ruthenium phosphine complex hydrogenates carbon dioxide to make methanol
(PDF)

Hydrogenation of Carbon Dioxide to Methanol by Using a Homogeneous Ruthenium–Phosphine Catalyst

Jürgen Klankermayer, RWTH Aachen University (Germany)


25/2012

DNA as Future Electronic Components
Conducting nanostructures based on metallized DNA
(PDF)

Surface "Click" Reaction of DNA followed by Directed Metalization for the Construction of Contactable Conducting Nanostructures

Ulrich Simon, RWTH Aachen University (Germany)


24/2012

Healing Bullets Fly Through Tissue
Ultrasound vaporization of microdroplets as propulsion for therapeutic micromachines
(PDF)

Acoustic Droplet Vaporization and Propulsion of Perfluorocarbon-Loaded Microbullets for Targeted Tissue Penetration and Deformation

Joseph Wang, University of California San Diego, La Jolla (USA)


23/2012

Rapid Test Uses Origami Technology
New concept for paper biosensors
(PDF)

Aptamer-Based Origami Paper Analytical Device for Electrochemical Detection of Adenosine

Richard M. Crooks, The University of Texas at Austin (USA)


22/2012

Painkiller by Photosynthesis
Selective and effective: silicon nanowires as photoelectrodes for carbon dioxide fixation
(PDF)

Silicon Nanowires as Photoelectrodes for Carbon Dioxide Fixation

Dunwei Wang, Boston College, Chestnut Hill (USA)


21/2012

Eggs on Stalks
Synthetic silk: researchers imitate the egg stalks of lacewings
(PDF)

Artificial Egg Stalks Made of a Recombinantly Produced Lacewing Silk Protein

Thomas Scheibel, Universität Bayreuth (Germany)


20/2012

Planned Coincidence
Antibody-based search for new chemical reactions
(PDF)

Reaction Discovery by Using a Sandwich Immunoassay

Frédéric Taran, CEA, iBiTecS, Gif-sur-Yvette (France)


19/2012

Synthetic Scent Hounds
Nanostructured sensor for the detection of very low concentrations of explosive
(PDF)

Bio-Inspired Nanostructured Sensor for the Detection of Ultralow Concentrations of Explosives

Denis Spitzer, Institut Franco-Allemand de Recherches de Saint-Louis (France)


18/2012

Is It Ripe?
Carbon nanotube-based ethylene sensor establishes fruit ripeness
(PDF)

Selective Detection of Ethylene Gas Using Carbon Nanotube-based Devices: Utility in Determination of Fruit Ripeness

Timothy M. Swager, Massachusetts Institute of Technology, Cambridge (USA)


17/2012

Test Result Written in Blood
Paper-based blood test provides “written report” of blood type
(PDF)

Paper-Based Blood Typing Device That Reports Patient's Blood Type "in Writing"

Wei Shen, Monash University, Clayton (Australia)


16/2012

Simulated Digestion
Nanomaterial made from lipids and silicon dioxide improves absorption of pharmaceuticals
(PDF)

Hybrid Nanomaterials that Mimic the Food Effect: Controlling Enzymatic Digestion for Enhanced Oral Drug Absorption

Clive A. Prestidge, University of South Australia, Mawson Lakes (Australia)


15/2012

A Two-Legged Molecule
A small molecule moves independently along a track
(PDF)

A Small Molecule that Walks Non-Directionally Along a Track Without External Intervention

David A. Leigh, University of Edinburgh (UK)


14/2012

The First Seconds in a Building’s Life
X-ray diffraction studies of cement hydration on the millisecond scale
(PDF)

First Seconds in a Building's Life—In Situ Synchrotron X-Ray Diffraction Study of Cement Hydration on the Millisecond Timescale

Franziska Emmerling, BAM Federal Institute of Materials Research and Testing, Berlin (Germany)


13/2012

Improved Mussel Adhesive
Biocompatible, waterproof, self-healing, and reversible: A new adhesive for medical applications?
(PDF)

Bioinspired Underwater Bonding and Debonding on Demand

Aránzazu del Campo, Max-Planck-Institut für Polymerforschung, Mainz (Germany)


12/2012

Everything Flows in Rapid Diagnostic Tests
A microfluidic electrochemical amplification technique allows for the rapid, sensitive, and quantitative detection of pathogenic DNA
(PDF)

Rapid, Sensitive, and Quantitative Detection of Pathogenic DNA at the Point of Care through Microfluidic Electrochemical Quantitative Loop-Mediated Isothermal Amplification

H. Tom Soh, University of California, Santa Barbara (USA)


11/2012

Fingerprints Tell All
Progress in fingerprint analysis
(PDF)

Advances in Fingerprint Analysis

David Russell, University of East Anglia, Norwich (UK)


10/2012

Glowing White
Solvent-free luminescent organic liquids for organic electronics
(PDF)

Solvent-Free Luminescent Organic Liquids

Takashi Nakanishi, National Institute for Materials Science, Tsukuba (Japan)


09/2012

Image or Mirror Image?
Chiral recognition by femtosecond laser
(PDF)

Circular Dichroism in the Photoelectron Angular Distributions of Camphor and Fenchone from Multiphoton Ionization with Femtosecond Laser Pulses

Thomas Baumert, Universität Kassel (Germany)


08/2012

Finding Cancer Cells in Blood
Chip-based method for the rapid, sensitive isolation of rare cells in blood
(PDF)

Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking

Daniel T. Chiu, University of Washington, Seattle (USA)


07/2012

Black Arsenic: Fact or Fiction?
Synthesis and identification of metastable compounds
(PDF)

Synthesis and Identification of Metastable Compounds: Black Arsenic—Science or Fiction?

Tom Nilges, Technische Universität München (Germany)


06/2012

Tiny Silver Particles Trap Mercury
Hyperstoichiometric reaction between mercury ions and silver nanoparticles
(PDF)

Hyperstoichiometric Interaction Between Silver and Mercury at the Nanoscale

Kseniia Katok, University of Brighton (UK)


05/2012

All Foamed Up
Synthesis of macroporous polystyrene through polymerization of foamed emulsions
(PDF)

Synthesis of Macroporous Polystyrene by the Polymerization of Foamed Emulsions

Cosima Stubenrauch, Universität Stuttgart (Germany)


04/2012

Precision Folds
Zinc-finger proteins act as site-specific adapters for DNA-origami structures
(PDF)

Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures

Takashi Morii, Kyoto University (Japan)


03/2012

Deadly Chinese Mushrooms
Mushroom amino acids revealed as cause of deaths in Yunnan province
(PDF)

Evidence for the Natural Toxins from the Mushroom Trogia venenata as a Cause of Sudden Unexplained Death in Yunnan Province, China

Ji-Kai Liu, Kunming Institute of Botany (China)


02/2012

Nothing but Air
Light but stable: novel cellulose–silica gel composite aerogels
(PDF)

Cellulose–Silica Nanocomposite Aerogels by In Situ Formation of Silica in Cellulose Gel

Jie Cai, Wuhan University (China)


01/2012

Recycling Platinum
Electrochemical dissolution of platinum in an ionic liquid
(PDF)

Heat-Assisted Electrodissolution of Platinum in an Ionic Liquid

Jing-Fang Huang, National Chung Hsing University (Taiwan, ROC)


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