Angewandte Chemie International Edition

Reviews: Nobel

Reviews in Angewandte Chemie, written by leading experts, summarize the important results of recent research on topical subjects in all branches of chemistry, point to unresolved problems, and discuss possible developments. The annual publication of the Nobel Lectures is of particular importance. Although review articles are generally written upon invitation of the editor, unsolicited manuscripts are also welcome provided they are in keeping with the character of the journal.

1962-1969 · 1970-1979 · 1980-1989 · 1990-1999 · 2000-2009 · 2010-2019 · Nobel · 

• Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot*, Victor Snieckus*
  Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
  Angew. Chem. 2012, 124, 5150–5174; Angew. Chem. Int. Ed. 2012, 51, 5062–5085
  Keywords: C-C coupling · Nobel Prize 2010 · cross-coupling · homogeneous catalysis · palladium
• Kostya S. Novoselov*
  Graphene: Materials in the Flatland (Nobel Lecture)
  Angew. Chem. 2011, 123, 7123–7141; Angew. Chem. Int. Ed. 2011, 50, 6986–7002
  Keywords: Nobel lectures · carbon · graphene · materials science · monolayers
• Andre K. Geim*
  Random Walk to Graphene (Nobel Lecture)
  Angew. Chem. 2011, 123, 7100–7122; Angew. Chem. Int. Ed. 2011, 50, 6966–6985
  Keywords: Nobel lectures · carbon · graphene · materials science · monolayers
• Ei-ichi Negishi*
  Magical Power of Transition Metals: Past, Present, and Future (Nobel Lecture)
  Angew. Chem. 2011, 123, 6870–6897; Angew. Chem. Int. Ed. 2011, 50, 6738–6764
  Keywords: Negishi coupling · carbometalation · cross-coupling · palladium
• Akira Suzuki*
  Cross-Coupling Reactions Of Organoboranes: An Easy Way To Construct C-C Bonds (Nobel Lecture)
  Angew. Chem. 2011, 123, 6854–6869; Angew. Chem. Int. Ed. 2011, 50, 6722–6737
  Keywords: Suzuki coupling · cross-coupling · organoboranes · palladium
• Carol W. Greider*
  Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle (Nobel Lecture)
  Angew. Chem. 2010, 122, 7582–7601; Angew. Chem. Int. Ed. 2010, 49, 7422–7439
  Keywords: DNA · Nobel lecture · telomerase · telomeres
• Elizabeth H. Blackburn*
  Telomeres and Telomerase: The Means to the End (Nobel Lecture)
  Angew. Chem. 2010, 122, 7564–7581; Angew. Chem. Int. Ed. 2010, 49, 7405–7421
  Keywords: DNA · Nobel lecture · telomerase · telomeres
• Jack W. Szostak*
  DNA Ends: Just the Beginning (Nobel Lecture)
  Angew. Chem. 2010, 122, 7544–7563; Angew. Chem. Int. Ed. 2010, 49, 7386–7404
  Keywords: DNA · Nobel lecture · telomerase · telomeres
• Thomas A. Steitz*
  From the Structure and Function of the Ribosome to New Antibiotics (Nobel Lecture)
  Angew. Chem. 2010, 122, 4482–4500; Angew. Chem. Int. Ed. 2010, 49, 4381–4398
  Keywords: Nobel lecture · antibiotics · protein synthesis · ribosomes
• V. Ramakrishnan*
  Unraveling the Structure of the Ribosome (Nobel Lecture)
  Angew. Chem. 2010, 122, 4454–4481; Angew. Chem. Int. Ed. 2010, 49, 4355–4380
  Keywords: Nobel lecture · antibiotics · protein synthesis · ribosomes
• Ada Yonath*
  Polar Bears, Antibiotics, and the Evolving Ribosome (Nobel Lecture)
  Angew. Chem. 2010, 122, 4438–4453; Angew. Chem. Int. Ed. 2010, 49, 4340–4354
  Keywords: Nobel lecture · antibiotics · protein synthesis · ribosomes
• Harald zur Hausen*
  The Search for Infectious Causes of Human Cancers: Where and Why (Nobel Lecture)
  Angew. Chem. 2009, 121, 5910–5920; Angew. Chem. Int. Ed. 2009, 48, 5798–5808
  Keywords: Nobel Lecture · cancer research · papillomaviruses · virology
• Françoise Barré-Sinoussi*
  HIV: A Discovery Opening the Road to Novel Scientific Knowledge and Global Health Improvement (Nobel Lecture)
  Angew. Chem. 2009, 121, 5910–5920; Angew. Chem. Int. Ed. 2009, 48, 5809–5814
  Keywords: AIDS · HIV · Nobel Lecture · virology
• Luc Montagnier*
  25 Years after HIV Discovery: Prospects for Cure and Vaccine (Nobel Lecture)
  Angew. Chem. 2009, 121, 5910–5920; Angew. Chem. Int. Ed. 2009, 48, 5815–5826
  Keywords: AIDS · HIV · Nobel Lecture · virology
• Roger Y. Tsien*
  Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture)
  Angew. Chem. 2009, 121, 5721–5736; Angew. Chem. Int. Ed. 2009, 48, 5612–5626
  Keywords: Nobel Lecture · fluorescent proteins · in vivo imaging · mutagenesis
• Martin Chalfie*
  GFP: Lighting Up Life (Nobel Lecture)
  Angew. Chem. 2009, 121, 5711–5720; Angew. Chem. Int. Ed. 2009, 48, 5603–5611
  Keywords: Nobel Lecture · fluorescent proteins · in vivo imaging · mutagenesis
• Osamu Shimomura*
  Discovery of Green Fluorescent Protein (GFP) (Nobel Lecture)
  Angew. Chem. 2009, 121, 5698–5710; Angew. Chem. Int. Ed. 2009, 48, 5590–5602
  Keywords: Nobel Lecture · aequorin · bioluminescence · fluorescent proteins
• Albert Fert*
  Origin, Development, and Future of Spintronics (Nobel Lecture)
  Angew. Chem. 2008, 120, 6042–6054; Angew. Chem. Int. Ed. 2008, 47, 5956–5967
  Keywords: Nobel lecture · giant magnetoresistance · magnetic properties · semiconductors · spintronics
• Gerhard Ertl*
  Reactions at Surfaces: From Atoms to Complexity (Nobel Lecture)
  Angew. Chem. 2008, 120, 3578–3590; Angew. Chem. Int. Ed. 2008, 47, 3524–3535
  Keywords: Nobel lecture · ammonia synthesis · carbon monoxide · oscillating reactions · surface chemistry
• Craig C. Mello*
  Return to the RNAi World: Rethinking Gene Expression and Evolution (Nobel Lecture)
  Angew. Chem. 2007, 119, 7114–7124; Angew. Chem. Int. Ed. 2007, 46, 6985–6994
  Keywords: Nobel Lecture · RNA interference · evolution · gene silencing
• Andrew Z. Fire*
  Gene Silencing by Double-Stranded RNA (Nobel Lecture)
  Angew. Chem. 2007, 119, 7094–7113; Angew. Chem. Int. Ed. 2007, 46, 6966–6984
  Keywords: Nobel Lecture · RNA interference · gene silencing · immunity · viruses
• Roger Kornberg*
  The Molecular Basis of Eukaryotic Transcription (Nobel Lecture)
  Angew. Chem. 2007, 119, 7082–7092; Angew. Chem. Int. Ed. 2007, 46, 6956–6965
  Keywords: Nobel Lecture · RNA polymerases · nucleosomes · structure elucidation · transcription
• Robert H. Grubbs*
  Olefin-Metathesis Catalysts for the Preparation of Molecules and Materials (Nobel Lecture)
  Angew. Chem. 2006, 118, 3845–3850; Angew. Chem. Int. Ed. 2006, 45, 3760–3765
  Keywords: Nobel lecture · homogeneous catalysis · metathesis · polymerization · ruthenium
• Richard R. Schrock*
  Multiple Metal–Carbon Bonds for Catalytic Metathesis Reactions (Nobel Lecture)
  Angew. Chem. 2006, 118, 3832–3844; Angew. Chem. Int. Ed. 2006, 45, 3748–3759
  Keywords: Nobel lecture · homogeneous catalysis · metathesis · molybdenum · tungsten
• Yves Chauvin*
  Olefin Metathesis: The Early Days (Nobel Lecture)
  Angew. Chem. 2006, 118, 3824–3831; Angew. Chem. Int. Ed. 2006, 45, 3740–3747
  Keywords: Nobel lecture · homogeneous catalysis · metathesis · polymerization · ruthenium
• Linda B. Buck*
  Unraveling the Sense of Smell (Nobel Lecture)
  Angew. Chem. 2005, 117, 6283–6296; Angew. Chem. Int. Ed. 2005, 44, 6128–6140
  Keywords: Nobel Lecture · brain research · fluorescence · olfactory cells · receptors
• Richard Axel*
  Scents and Sensibility: A Molecular Logic of Olfactory Perception (Nobel Lecture)
  Angew. Chem. 2005, 117, 6264–6282; Angew. Chem. Int. Ed. 2005, 44, 6110–6127
  Keywords: Nobel Lecture · brain research · fluorescence · olfactory cells · receptors
• Aaron Ciechanover*
  Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin–Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)
  Angew. Chem. 2005, 117, 6095–6119; Angew. Chem. Int. Ed. 2005, 44, 5944–5967
  Keywords: Nobel Lecture · lysosomes · proteasomes · protein breakdown · ubiquitin
• Avram Hershko*
  The Ubiquitin System for Protein Degradation and Some of Its Roles in the Control of the Cell-Division Cycle (Nobel Lecture)
  Angew. Chem. 2005, 117, 6082–6094; Angew. Chem. Int. Ed. 2005, 44, 5932–5943
  Keywords: Nobel Lecture · biochemistry · cell division · protein breakdown · ubiquitin
• Irwin Rose*
  Ubiquitin at Fox Chase (Nobel Lecture)
  Angew. Chem. 2005, 117, 6076–6081; Angew. Chem. Int. Ed. 2005, 44, 5926–5931
  Keywords: Nobel lecture · enzymes · protein breakdown · ubiquitin
• Paul C. Lauterbur*
  All Science Is Interdisciplinary—From Magnetic Moments to Molecules to Men (Nobel Lecture)
  Angew. Chem. 2005, 117, 1026–1034; Angew. Chem. Int. Ed. 2005, 44, 1004–1011
  Keywords: NMR spectroscopy · Nobel Lecture · imaging techniques
• Peter Mansfield*
  Snapshot Magnetic Resonance Imaging (Nobel Lecture)
  Angew. Chem. 2004, 116, 5572–5580; Angew. Chem. Int. Ed. 2004, 43, 5456–5464
  Keywords: NMR spectroscopy · Nobel Lecture · imaging techniques · magnetic resonance imaging
• Peter Agre*
  Aquaporin Water Channels (Nobel Lecture)
  Angew. Chem. 2004, 116, 4377–4390; Angew. Chem. Int. Ed. 2004, 43, 4278–4290
  Keywords: Nobel lecture · aquaporins · medicinal chemistry · membrane proteins · protein structures
• Roderick MacKinnon*
  Potassium Channels and the Atomic Basis of Selective Ion Conduction (Nobel Lecture)
  Angew. Chem. 2004, 116, 4363–4376; Angew. Chem. Int. Ed. 2004, 43, 4265–4277
  Keywords: Nobel Lecture · ion channels · membranes · protein structures · structure elucidation
• John B. Fenn*
  Electrospray Wings for Molecular Elephants (Nobel Lecture)
  Angew. Chem. 2003, 115, 3999–4024; Angew. Chem. Int. Ed. 2003, 42, 3871–3894
  Keywords: Nobel lecture · analytical chemistry · electrospray ionization · history of science · mass spectrometry
• Koichi Tanaka*
  The Origin of Macromolecule Ionization by Laser Irradiation (Nobel Lecture)
  Angew. Chem. 2003, 115, 3989–3998; Angew. Chem. Int. Ed. 2003, 42, 3860–3870
  Keywords: Nobel lecture · laser desorption · macromolecules · mass spectrometry
• Kurt Wüthrich*
  NMR Studies of Structure and Function of Biological Macromolecules (Nobel Lecture)
  Angew. Chem. 2003, 115, 3462–3486; Angew. Chem. Int. Ed. 2003, 42, 3340–3363
  Keywords: NMR spectroscopy · Nobel lecture · proteins · structure determination
• K. Barry Sharpless*
  Searching for New Reactivity (Nobel Lecture)
  Angew. Chem. 2002, 114, 2126–2135; Angew. Chem. Int. Ed. 2002, 41, 2024–2032
  Keywords: N ligands · Nobel lecture · asymmetric catalysis · epoxidation · hydroxylation
• Ryoji Noyori*
  Asymmetric Catalysis: Science and Opportunities (Nobel Lecture)
  Angew. Chem. 2002, 114, 2108–2123; Angew. Chem. Int. Ed. 2002, 41, 2008–2022
  Keywords: Nobel lecture · asymmetric catalysis · asymmetric hydrogenation · phosphane ligands · ruthenium
• William S. Knowles*
  Asymmetric Hydrogenations (Nobel Lecture)
  Angew. Chem. 2002, 114, 2096–2107; Angew. Chem. Int. Ed. 2002, 41, 1998–2007
  Keywords: Nobel lecture · asymmetric catalysis · asymmetric hydrogenation · phosphane ligands · rhodium
• Alan J. Heeger*
  Semiconducting and Metallic Polymers: The Fourth Generation of Polymeric Materials (Nobel Lecture)
  Angew. Chem. 2001, 113, 2660–2682; Angew. Chem. Int. Ed. 2001, 40, 2591–2611
  Keywords: Nobel lecture · chemical doping · conducting materials · polyacetylene · solid-state physics
• Alan G. MacDiarmid*
  “Synthetic Metals”: A Novel Role for Organic Polymers (Nobel Lecture)
  Angew. Chem. 2001, 113, 2649–2659; Angew. Chem. Int. Ed. 2001, 40, 2581–2590
  Keywords: Nobel lecture · conducting materials · liquid crystals · nano-electronics · polymers
• Hideki Shirakawa*
  The Discovery of Polyacetylene Film: The Dawning of an Era of Conducting Polymers (Nobel Lecture)
  Angew. Chem. 2001, 113, 2642–2648; Angew. Chem. Int. Ed. 2001, 40, 2574–2580
  Keywords: Nobel lecture · Ziegler-Natta · chemical doping · conducting materials · polyacetylene
• Ahmed H. Zewail*
  Femtochemistry: Atomic-Scale Dynamics of the Chemical Bond Using Ultrafast Lasers (Nobel Lecture)
  Angew. Chem. 2000, 112, 2688–2738; Angew. Chem. Int. Ed. 2000, 39, 2586–2631
  Keywords: Nobel lecture · femtobiology · femtochemistry · physical chemistry · transition states
• John A. Pople*
  Quantum Chemical Models (Nobel Lecture)
  Angew. Chem. 1999, 111, 2014–2023; Angew. Chem. Int. Ed. 1999, 38, 1894–1902
  Keywords: Ab initio calculations · Computer chemistry · Nobel lecture · Theoretical chemistry
• Louis J. Ignarro*
  Nitric Oxide: A Unique Endogenous Signaling Molecule in Vascular Biology (Nobel Lecture)
  Angew. Chem. 1999, 111, 2002–2013; Angew. Chem. Int. Ed. 1999, 38, 1882–1892
  Keywords: Enzymes · Neurotransmitters · Nitric oxide · Nobel lecture · Signal transduction
• Robert F. Furchgott
  Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identifcation as Nitric Oxide (Nobel Lecture)
  Angew. Chem. 1999, 111, 1976–1989; Angew. Chem. Int. Ed. 1999, 38, 1870–1880
  Keywords: Enzymes · Neurotransmitters · Nitric oxide · Nobel lecture · Signal transduction
• Ferid Murad*
  Discovery of Some of the Biological Effects of Nitric Oxide and Its Role in Cell Signaling (Nobel Lecture)
  Angew. Chem. 1999, 111, 1976–1989; Angew. Chem. Int. Ed. 1999, 38, 1856–1868
  Keywords: Enzymes · Nitric oxide · Nobel lecture · Nucleotides · Signal transduction
• John E. Walker*
  ATP Synthesis by Rotary Catalysis (Nobel lecture)
  Angew. Chem. 1998, 110, 2438–2450; Angew. Chem. Int. Ed. 1998, 37, 2308–2319
  Keywords: ATP · Bioenergetics · Enzyme catalysis · Nobel lecture · Protein structures
• Paul D. Boyer*
  Energy, Life, and ATP (Nobel Lecture)
  Angew. Chem. 1998, 110, 2424–2436; Angew. Chem. Int. Ed. 1998, 37, 2296–2307
  Keywords: ATP · Bioenergetics · Enzyme catalysis · Nobel lecture · Phosphorylations
• Jens C. Skou
  The Identification of the Sodium–Potassium Pump (Nobel Lecture)
  Angew. Chem. 1998, 110, 2424–2436; Angew. Chem. Int. Ed. 1998, 37, 2320–2328
  Keywords: ATP · Ion transport · Membranes · Nobel lecture · Sodium-potassium pump
• Rolf M. Zinkernagel*
  Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens (Nobel Lecture)
  Angew. Chem. 1997, 109, 2026–2038; Angew. Chem. Int. Ed. Engl. 1997, 36, 1938–1949
  Keywords: Antigens · Immunochemistry · MHC (major histocompatibility complex) · Nobel lecture · T cells
• Peter C. Doherty*
  Cell-Mediated Immunity in Virus Infections (Nobel Lecture)
  Angew. Chem. 1997, 109, 2014–2025; Angew. Chem. Int. Ed. Engl. 1997, 36, 1926–1936
  Keywords: Antigens · Immunochemistry · MHC (major histocompatibility complex) · Nobel lecture · T cells
• Richard E. Smalley*
  Discovering the Fullerenes (Nobel Lecture)
  Angew. Chem. 1997, 109, 1666–1673; Angew. Chem. Int. Ed. Engl. 1997, 36, 1594–1601
  Keywords: Carbon allotropes · Fullerenes · Nanostructures · Nobel lecture
• Harold W. Kroto*
  Symmetry, Space, Stars, and C₆₀ (Nobel Lecture)
  Angew. Chem. 1997, 109, 1648–1664; Angew. Chem. Int. Ed. Engl. 1997, 36, 1578–1593
  Keywords: Carbon allotropes · Fullerenes · Nanostructures · Nobel lecture
• Robert F. Curl*
  Dawn of the Fullerenes: Conjecture and Experiment (Nobel Lecture)
  Angew. Chem. 1997, 109, 1636–1647; Angew. Chem. Int. Ed. Engl. 1997, 36, 1566–1576
  Keywords: Carbon allotropes · Fullerenes · Nanostructures · Nobel lecture
• Eric Wieschaus*
  From Molecular Patterns to Morphogenesis—The Lessons from Studies on the Fruit Fly Drosophila (Nobel Lecture)
  Angew. Chem. 1996, 108, 2330–2337; Angew. Chem. Int. Ed. Engl. 1996, 35, 2188–2194
  Keywords: Drosophila · Embryonic development · Fruit flies · Nobel lecture
• Christiane Nüsslein-Volhard*
  The Identification of Genes Controlling Development in Flies and Fishes (Nobel Lecture)
  Angew. Chem. 1996, 108, 2316–2328; Angew. Chem. Int. Ed. Engl. 1996, 35, 2176–2187
  Keywords: Drosophila · Fruit flies · Gene identification · Nobel lecture
• F. Sherwood Rowland*
  Stratospheric Ozone Depletion by Chlorofluorocarbons (Nobel Lecture)
  Angew. Chem. 1996, 108, 1908–1921; Angew. Chem. Int. Ed. Engl. 1996, 35, 1786–1798
  Keywords: Atmospheric chemistry · Nobel lecture · Ozone
• Mario J. Molina*
  Polar Ozone Depletion (Nobel Lecture)
  Angew. Chem. 1996, 108, 1900–1907; Angew. Chem. Int. Ed. Engl. 1996, 35, 1778–1785
  Keywords: Atmospheric chemistry · Nobel lecture · Ozone
• Paul J. Crutzen*
  My Life with O₃, NO_x, and Other YZO_x Compounds (Nobel Lecture)
  Angew. Chem. 1996, 108, 1878–1898; Angew. Chem. Int. Ed. Engl. 1996, 35, 1758–1777
  Keywords: Atmospheric chemistry · Nobel lecture · Ozone
• Martin Rodbell*
  Signal Transduction: Evolution of an Idea (Nobel Lecture)
  Angew. Chem. 1995, 107, 1549–1558; Angew. Chem. Int. Ed. Engl. 1995, 34, 1420–1428
  Keywords: G proteins · Nobel lecture · Signal transduction
• Alfred G. Gilman*
  G Proteins and Regulation of Adenylate Cyclase (Nobel Lecture)
  Angew. Chem. 1995, 107, 1533–1548; Angew. Chem. Int. Ed. Engl. 1995, 34, 1406–1419
  Keywords: Adenylate cyclase · G proteins · Nobel lecture
• George A. Olah*
  My Search for Carbocations and Their Role in Chemistry (Nobel Lecture)
  Angew. Chem. 1995, 107, 1519–1532; Angew. Chem. Int. Ed. Engl. 1995, 34, 1393–1405
  Keywords: Carbocations · Hydrocarbons · Nobel lecture · Reactive intermediates
• Phillip A. Sharp*
  Split Genes and RNA Splicing (Nobel Lecture)
  Angew. Chem. 1994, 106, 1292–1304; Angew. Chem. Int. Ed. Engl. 1994, 33, 1229–1240
  Keywords: Nobel lecture · RNA · RNA splicing
• Richard J. Roberts*
  An Amazing Distortion in DNA Induced by a Methyltransferase (Nobel Lecture)
  Angew. Chem. 1994, 106, 1285–1291; Angew. Chem. Int. Ed. Engl. 1994, 33, 1222–1228
  Keywords: DNA · DNA methylation · Nobel lecture
• Michael Smith*
  Synthetic DNA and Biology (Nobel Lecture)
  Angew. Chem. 1994, 106, 1277–1284; Angew. Chem. Int. Ed. Engl. 1994, 33, 1214–1221
  Keywords: DNA · Nobel lecture · Oligonucleotides
• Kary B. Mullis*
  The Polymerase Chain Reaction (Nobel Lecture)
  Angew. Chem. 1994, 106, 1271–1276; Angew. Chem. Int. Ed. Engl. 1994, 33, 1209–1213
  Keywords: Nobel lecture · Polymerase chain reaction
• Edmond H. Fischer*
  Protein Phosphorylation and Cellular Regulation II (Nobel Lecture)
  Angew. Chem. 1993, 105, 1181–1188; Angew. Chem. Int. Ed. Engl. 1993, 32, 1130–1137
  Keywords: Cellular regulation · Nobel lecture · Phosphorylation · Proteins
• Edwin G. Krebs*
  Protein Phosphorylation and Cellular Regulation I (Nobel Lecture)
  Angew. Chem. 1993, 105, 1173–1180; Angew. Chem. Int. Ed. Engl. 1993, 32, 1122–1129
  Keywords: Cellular regulation · Nobel lecture · Phosphorylation · Proteins
• Rudolph A. Marcus*
  Electron Transfer Reactions in Chemistry: Theory and Experiment (Nobel Lecture)
  Angew. Chem. 1993, 105, 1161–1172; Angew. Chem. Int. Ed. Engl. 1993, 32, 1111–1121
  Keywords: Electron transfer · Nobel lecture · Reaction mechanisms
• Pierre-Gilles de Gennes*
  Soft Matter (Nobel Lecture)
  Angew. Chem. 1992, 104, 856–859; Angew. Chem. Int. Ed. Engl. 1992, 31, 842–845
  Keywords: Fluids · Liquid crystals · Nobel lecture · Polymers · Soft matter · Surfactants
• Bert Sakmann*
  Elementary Steps in Synaptic Transmission Revealed by Currents through Single Ion Channels (Nobel Lecture)
  Angew. Chem. 1992, 104, 844–856; Angew. Chem. Int. Ed. Engl. 1992, 31, 830–841
  Keywords: Cells · Ion channels · Nobel lecture
• Erwin Neher*
  Ion Channels for Communication Between and Within Cells (Nobel Lecture)
  Angew. Chem. 1992, 104, 837–843; Angew. Chem. Int. Ed. Engl. 1992, 31, 824–829
  Keywords: Cells · Ion channels · Nobel lecture
• Richard R. Ernst*
  Nuclear Magnetic Resonance Fourier Transform Spectroscopy (Nobel Lecture)
  Angew. Chem. 1992, 104, 817–836; Angew. Chem. Int. Ed. Engl. 1992, 31, 805–823
  Keywords: NMR spectroscopy · Nobel lecture
• Elias James Corey*
  The Logic of Chemical Synthesis: Multistep Synthesis of Complex Carbogenic Molecules (Nobel Lecture)
  Angew. Chem. 1991, 103, 469–479; Angew. Chem. Int. Ed. Engl. 1991, 30, 455–465
  Keywords: Computer chemistry · Nobel lecture · Retro reactions · Synthetic methods
• Norman F. Ramsey*
  Experiments with Separated Oscillatory Fields and Hydrogen Masers (Nobel Lecture)
  Angew. Chem. 1990, 102, 790–798; Angew. Chem. Int. Ed. Engl. 1990, 29, 725–733
  Keywords: Masers · Molecular beam studies · Nobel lecture · Precision spectroscopy
• Wolfgang Paul*
  Electromagnetic Traps for Charged and Neutral Particles (Nobel Lecture)
  Angew. Chem. 1990, 102, 780–789; Angew. Chem. Int. Ed. Engl. 1990, 29, 739–748
  Keywords: Ion traps · Nobel lecture · Precision spectroscopy
• Hans Dehmelt*
  Experiments with an Isolated Subatomic Particle at Rest (Nobel Lecture)
  Angew. Chem. 1990, 102, 774–779; Angew. Chem. Int. Ed. Engl. 1990, 29, 734–738
  Keywords: Ion traps · Nobel lecture · Precision spectroscopy
• J. Michael Bishop*
  Retroviruses and Oncogenes II (Nobel Lecture)
  Angew. Chem. 1990, 102, 765–773; Angew. Chem. Int. Ed. Engl. 1990, 29, 716–724
  Keywords: Nobel lecture · Oncogenes · Retroviruses
• Harold E. Varmus*
  Retroviruses and Oncogenes I (Nobel Lecture)
  Angew. Chem. 1990, 102, 756–764; Angew. Chem. Int. Ed. Engl. 1990, 29, 707–715
  Keywords: Nobel lecture · Oncogenes · Retroviruses
• Thomas R. Cech*
  Self-splicing and Enzymatic Activity of an Intervening Sequence RNA from Tetrahymena (Nobel Lecture)
  Angew. Chem. 1990, 102, 745–755; Angew. Chem. Int. Ed. Engl. 1990, 29, 759–768
  Keywords: Enzyme activity · Nobel lecture · Nucleic acids · RNA cleavage · Self splicing
• Sidney Altman*
  Enzymatic Cleavage of RNA by RNA (Nobel Lecture)
  Angew. Chem. 1990, 102, 735–744; Angew. Chem. Int. Ed. Engl. 1990, 29, 749–758
  Keywords: Enzyme activity · Nobel lecture · Nucleic acids · RNA cleavage
• James W. Black*
  Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism (Nobel Lecture)
  Angew. Chem. 1989, 101, 910–919; Angew. Chem. Int. Ed. Engl. 1989, 28, 886–894
  Keywords: Drug research · Hormone antagonists · Nobel lecture · Syntopic antagonism
• George H. Hitchings, Jr.*
  Selective Inhibitors of Dihydrofolate Reductase (Nobel Lecture)
  Angew. Chem. 1989, 101, 903–909; Angew. Chem. Int. Ed. Engl. 1989, 28, 879–885
  Keywords: Dihydrofolate reductase · Drug research · Enzymes · Inhibitors · Nobel lecture · Reductase
• Gertrude B. Elion*
  The Purine Path to Chemotherapy (Nobel Lecture)
  Angew. Chem. 1989, 101, 893–902; Angew. Chem. Int. Ed. Engl. 1989, 28, 870–878
  Keywords: Drug research · Nobel lecture · Purine path
• Johann Deisenhofer*, Hartmut Michel*
  The Photosynthetic Reaction Center from the Purple Bacterium Rhodopseudomonas viridis (Nobel Lecture)
  Angew. Chem. 1989, 101, 872–892; Angew. Chem. Int. Ed. Engl. 1989, 28, 829–847
  Keywords: Nobel lecture · Photosynthesis · Proteins · Purple bacterium · X-ray structure analysis
• Robert Huber*
  A Structural Basis of Light Energy and Electron Transfer in Biology (Nobel Lecture)
  Angew. Chem. 1989, 101, 849–871; Angew. Chem. Int. Ed. Engl. 1989, 28, 848–869
  Keywords: Electron transfer · Light energy transfer · Nobel lecture · Photosynthesis · Phycobilisomes · Protein-cofactor complexes · Purple bacterium · X-ray structure analysis
• Susumu Tonegawa*
  Somatic Generation of Immune Diversity (Nobel Lecture)
  Angew. Chem. 1988, 100, 1060–1071; Angew. Chem. Int. Ed. Engl. 1988, 27, 1028–1039
  Keywords: Antigens · Immunochemistry · Nobel lecture
• Charles J. Pedersen*
  The Discovery of Crown Ethers (Nobel Lecture)
  Angew. Chem. 1988, 100, 1053–1059; Angew. Chem. Int. Ed. Engl. 1988, 27, 1021–1027
  Keywords: Crown compounds · Macrocycles · Nobel lecture
• Donald J. Cram*
  The Design of Molecular Hosts, Guests, and Their Complexes (Nobel Lecture)
  Angew. Chem. 1988, 100, 1041–1052; Angew. Chem. Int. Ed. Engl. 1988, 27, 1009–1020
  Keywords: Host-guest chemistry · Macrocycles · Nobel lecture · Supramolecular chemistry
• Jean-Marie Lehn*
  Supramolecular Chemistry—Scope and Perspectives—Molecules, Supermolecules, and Molecular Devices (Nobel Lecture)
  Angew. Chem. 1988, 100, 91–116; Angew. Chem. Int. Ed. Engl. 1988, 27, 89–112
  Keywords: Macrocycles · Molecular recognition · Nobel lecture · Supramolecular chemistry
• Dudley R. Herschbach*
  Molecular Dynamics of Elementary Chemical Reactions (Nobel Lecture)
  Angew. Chem. 1987, 99, 1251–1275; Angew. Chem. Int. Ed. Engl. 1987, 26, 1221–1243
  Keywords: Elementary chemical processes · Molecular dynamics · Nobel lecture · Reaction dynamics
• John C. Polanyi*
  Some Concepts in Reaction Dynamics (Nobel Lecture)
  Angew. Chem. 1987, 99, 981–1001; Angew. Chem. Int. Ed. Engl. 1987, 26, 952–971
  Keywords: Elementary chemical processes · Nobel lecture · Reaction dynamics
• Yuan Tseh Lee*
  Molecular Beam Studies of Elementary Chemical Processes (Nobel Lecture)
  Angew. Chem. 1987, 99, 967–980; Angew. Chem. Int. Ed. Engl. 1987, 26, 939–951
  Keywords: Elementary chemical processes · Molecular beam studies · Nobel lecture · Reaction dynamics
• Stanley Cohen*
  Epidermal Growth Factor (Nobel Lecture)
  Angew. Chem. 1987, 99, 738–744; Angew. Chem. Int. Ed. Engl. 1987, 26, 717–722
  Keywords: Epidermal growth factor · Growth factor · Nobel lecture · Proteins
• Rita Levi-Montalcini*
  The Nerve Growth Factor: 35 Years Later (Nobel Lecture)
  Angew. Chem. 1987, 99, 727–737; Angew. Chem. Int. Ed. Engl. 1987, 26, 707–716
  Keywords: Growth factor · Nerve growth factor · Nobel lecture · Proteins
• Gerd Binnig*, Heinrich Rohrer*
  Scanning Tunneling Microscopy—From Birth to Adolescence (Nobel Lecture)
  Angew. Chem. 1987, 99, 622–631; Angew. Chem. Int. Ed. Engl. 1987, 26, 606–614
  Keywords: Electron microscopy · Nobel lecture · Scanning probe microscopy
• Ernst Ruska*
  The Development of the Electron Microscope and of Electron Microscopy (Nobel Lecture)
  Angew. Chem. 1987, 99, 611–621; Angew. Chem. Int. Ed. Engl. 1987, 26, 595–605
  Keywords: Electron microscopy · Nobel lecture
• Jerome Karle*
  Recovering Phase Information from Intensity Data (Nobel Lecture)
  Angew. Chem. 1986, 98, 611–626; Angew. Chem. Int. Ed. Engl. 1986, 25, 614–629
  Keywords: Nobel lecture · X-ray structure analysis
• Herbert Hauptman*
  Direct Methods and Anomalous Dispersion (Nobel Lecture)
  Angew. Chem. 1986, 98, 600–610; Angew. Chem. Int. Ed. Engl. 1986, 25, 603–613
  Keywords: Nobel lecture · X-ray structure analysis
• Michael S. Brown*, Joseph L. Goldstein
  A Receptor-Mediated Pathway for Cholesterol Homeostasis (Nobel Lecture)
  Angew. Chem. 1986, 98, 579–599; Angew. Chem. Int. Ed. Engl. 1986, 25, 583–602
  Keywords: Catalysis · Cholesterol homeostasis · Nobel lecture · Receptors
• Georges Köhler*
  Derivation and Diversification of Monoclonal Antibodies (Nobel Lecture)
  Angew. Chem. 1985, 97, 829–836; Angew. Chem. Int. Ed. Engl. 1985, 24, 827–833
  Keywords: Antibodies · Monoclonal antibodies · Nobel lecture
• Cesar Milstein*
  From the Structure of Antibodies to the Diversification of the Immune Response (Nobel Lecture)
  Angew. Chem. 1985, 97, 819–828; Angew. Chem. Int. Ed. Engl. 1985, 24, 816–826
  Keywords: Antibodies · Immunochemistry · Nobel lecture
• Niels K. Jerne*
  The Generative Grammar of the Immune System (Nobel Lecture)
  Angew. Chem. 1985, 97, 813–818; Angew. Chem. Int. Ed. Engl. 1985, 24, 810–816
  Keywords: Grammar · Immunochemistry · Nobel lecture
• Robert Bruce Merrifield*
  Solid Phase Synthesis (Nobel Lecture)
  Angew. Chem. 1985, 97, 801–812; Angew. Chem. Int. Ed. Engl. 1985, 24, 799–810
  Keywords: Merrifield synthesis · Nobel lecture · Peptides · Solid-phase synthesis
• William A. Fowler*
  Experimental and Theoretical Nuclear Astrophysics; The Quest for the Origin of the Elements (Nobel Lecture)
  Angew. Chem. 1984, 96, 662–690; Angew. Chem. Int. Ed. Engl. 1984, 23, 645–671
  Keywords: Astrophysics · Elements · Nobel lecture
• Subrahmanyan Chandrasekhar*
  On Stars, Their Evolution and Their Stability (Nobel Lecture)
  Angew. Chem. 1984, 96, 651–661; Angew. Chem. Int. Ed. Engl. 1984, 23, 679–689
  Keywords: Astrophysics · Nobel lecture · Stars
• Henry Taube*
  Electron Transfer between Metal Complexes—A Retrospective View (Nobel Lecture)
  Angew. Chem. 1984, 96, 315–326; Angew. Chem. Int. Ed. Engl. 1984, 23, 329–339
  Keywords: Complexes · Electron transfer · Nobel lecture
• Sune Bergström*
  The Prostaglandins: From the Laboratory to the Clinic (Nobel Lecture)
  Angew. Chem. 1983, 95, 865–873; Angew. Chem. Int. Ed. Engl. 1983, 22, 858–866
  Keywords: Nobel lecture · Prostaglandins
• Bengt Samuelsson*
  From Studies of Biochemical Mechanism to Novel Biological Mediators: Prostaglandin Endoperoxides, Thromboxanes, and Leukotrienes (Nobel Lecture)
  Angew. Chem. 1983, 95, 854–864; Angew. Chem. Int. Ed. Engl. 1983, 22, 805–815
  Keywords: Leukotrienes · Nobel lecture · Prostaglandins · Thromboxanes
• John R. Vane*
  Adventures and Excursions in Bioassay: The Stepping Stones to Prostacyclin (Nobel Lecture)
  Angew. Chem. 1983, 95, 782–794; Angew. Chem. Int. Ed. Engl. 1983, 22, 741–752
  Keywords: Bioassay · Nobel lecture · Prostacyclins
• Aaron Klug*
  From Macromolecules to Biological Assemblies (Nobel Lecture)
  Angew. Chem. 1983, 95, 579–596; Angew. Chem. Int. Ed. Engl. 1983, 22, 565–582
  Keywords: Nobel lecture · Nucleic acids · Proteins · Tobacco mosaic virus
• Kenichi Fukui*
  The Role of Frontier Orbitals in Chemical Reactions (Nobel Lecture)
  Angew. Chem. 1982, 94, 852–861; Angew. Chem. Int. Ed. Engl. 1982, 21, 801–809
  Keywords: Frontier orbitals · Nobel lecture · Semiempirical calculations
• Roald Hoffmann*
  Building Bridges between Inorganic and Organic Chemistry (Nobel Lecture)
  Angew. Chem. 1982, 94, 725–739; Angew. Chem. Int. Ed. Engl. 1982, 21, 711–724
  Keywords: Isolobal relationship · Nobel lecture · Orbital symmetry
• Walter Gilbert*
  DNA-Sequenzierung und Gen-Struktur (Nobel Lecture)
  Angew. Chem. 1981, 93, 1037–1046
• Frederick Sanger*
  Bestimmung von Nucleotidsequenzen der DNA (Nobel Lecture)
  Angew. Chem. 1981, 93, 937–944
• Paul Berg*
  Zerlegung und Rekonstruktion von Genen und Chromosomen (Nobel Lecture)
  Angew. Chem. 1981, 93, 885–893
• Herbert C. Brown*
  Aus kleinen Eicheln wachsen große Eichen – von den Boranen zu den Organoboranen (Nobel Lecture)
  Angew. Chem. 1980, 92, 675–683
• Georg Wittig*
  Von Diylen über Ylide zu meinem Idyll (Nobel Lecture)
  Angew. Chem. 1980, 92, 671–675
• Peter D. Mitchell*
  David Keilins Konzept der Atmungskette und dessen chemiosmotische Konsequenzen (Nobel Lecture)
  Angew. Chem. 1979, 91, 718–733
• Ilya Prigogine*
  Zeit, Struktur und Fluktuationen (Nobel Lecture)
  Angew. Chem. 1978, 90, 704–715
• William N. Lipscomb*
  Die Borane und ihre Derivate (Nobel Lecture)
  Angew. Chem. 1977, 89, 685–696
• John Warcup Cornforth*
  Asymmetrie und Enzymwirkung (Nobel Lecture)
  Angew. Chem. 1976, 88, 550–555
• Paul J. Flory*
  Die Konformation linearer Makromoleküle (Nobel Lecture)
  Angew. Chem. 1975, 87, 787–797
• Geoffrey Wilkinson*
  Die lange Suche nach stabilen Alkyl-Übergangsmetall-Verbindungen (Nobel Lecture)
  Angew. Chem. 1974, 86, 664–667
• Ernst Otto Fischer*
  Auf dem Weg zu Carben- und Carbin-Komplexen (Nobel Lecture)
  Angew. Chem. 1974, 86, 651–663
• Rodney R. Porter*
  Strukturuntersuchungen an Immunglobulinen (Nobel Lecture)
  Angew. Chem. 1973, 85, 1097–1101
• Gerald M. Edelman*
  Antikörperstruktur und molekulare Immunologie (Nobel Lecture)
  Angew. Chem. 1973, 85, 1083–1096
• Stanford Moore*, William H. Stein*
  Die chemische Struktur der Pankreas-Ribonuclease und -Desoxyribonuclease (Nobel Lecture)
  Angew. Chem. 1973, 85, 1074–1083
• Christian B. Anfinsen*
  Untersuchungen über die Ursachen der Faltung von Proteinketten (Nobel Lecture)
  Angew. Chem. 1973, 85, 1065–1074
• Gerhard Herzberg*
  Spektroskopische Untersuchung von Molekülstrukturen (Nobel Lecture)
  Angew. Chem. 1972, 84, 1126–1142
• Earl W. Sutherland, Jr.*
  Untersuchungen zur Wirkungsweise der Hormone (Nobel Lecture)
  Angew. Chem. 1972, 84, 1117–1125
• Louis Néel*
  Magnetismus und lokales Molekularfeld (Nobel Lecture)
  Angew. Chem. 1971, 83, 838–848
• Julius Axelrod*
  Noradrenalin: Abbau und Regulation seiner Biosynthese (Nobel Lecture)
  Angew. Chem. 1971, 83, 827–837
• Ulf S. von Euler*
  Die Wirkungsweise des adrenergen neuronalen Überträgerstoffs (Nobel Lecture)
  Angew. Chem. 1971, 83, 822–827
• Bernard Katz*
  Über die Freisetzung des Überträgerstoffs aus den Nerven in Form von Quanten (Nobel Lecture)
  Angew. Chem. 1971, 83, 818–821
• Luis F. Leloir*
  Zwei Jahrzehnte Forschung über die Biosynthese von Sacchariden (Nobel Lecture)
  Angew. Chem. 1971, 83, 813–818
• Salvador E. Luria*
  Phagen, Colicine und makroregulatorische Phänomene (Nobel Lecture)
  Angew. Chem. 1970, 82, 947–952
• Alfred D. Hershey*
  Idiosynkrasien der DNA-Struktur (Nobel Lecture)
  Angew. Chem. 1970, 82, 943–946
• Derek H. R. Barton*
  Die Prinzipien der Konformationsanalyse (Nobel Lecture)
  Angew. Chem. 1970, 82, 827–834
• Odd Hassel*
  Strukturelle Aspekte der interatomaren Charge-transfer-Bindung (Nobel Lecture)
  Angew. Chem. 1970, 82, 821–827
• Robert W. Holley*
  Alanin-Transfer-RNA (Nobel Lecture)
  Angew. Chem. 1969, 81, 1039–1045
• Har Gobind Khorana*
  Nucleinsäure-Synthese als Werkzeug für das Studium des genetischen Codes (Nobel Lecture)
  Angew. Chem. 1969, 81, 1027–1039
• Marshall W. Nirenberg*
  Der genetische Code (Nobel Lecture)
  Angew. Chem. 1969, 81, 1017–1027
• Lars Onsager*
  Die Bewegung von Ionen: Prinzipien und Vorstellungen (Nobel Lecture)
  Angew. Chem. 1969, 81, 1009–1016
• Manfred Eigen*
  Die „unmeßbar“ schnellen Reaktionen (Nobel Lecture)
  Angew. Chem. 1968, 80, 892–906
• George Porter*
  Die Blitzlichtphotolyse und einige ihrer Anwendungen (Nobel Lecture)
  Angew. Chem. 1968, 80, 882–891
• Ronald George Wreyford Norrish*
  Untersuchungen einiger schneller Reaktionen in Gasen durch Blitzlichtphotolyse und kinetische Spektroskopie (Nobel Lecture)
  Angew. Chem. 1968, 80, 868–881
• George Wald*
  Die molekulare Basis des Sehvorgangs (Nobel Lecture)
  Angew. Chem. 1968, 80, 857–867
• Robert S. Mulliken*
  Spektroskopie, Molekül-Orbitale und chemische Bindung (Nobel Lecture)
  Angew. Chem. 1967, 79, 541–554
• François Jacob*
  Genetik der Bakterienzelle (Nobel Lecture)
  Angew. Chem. 1966, 78, 704–713
• Jacques Monod*
  Von der enzymatischen Adaptation zur allosterischen Umlagerung (Nobel Lecture)
  Angew. Chem. 1966, 78, 694–703
• André Lwoff*
  Virus, Zelle, Organismus (Nobel Lecture)
  Angew. Chem. 1966, 78, 689–694
• Robert Burns Woodward*
  Neueste Fortschritte in der Chemie der Naturstoffe (Nobel Lecture)
  Angew. Chem. 1966, 78, 557–564
• Dorothy Crowfoot-Hodgkin*
  Die Röntgenstrukturanalyse komplizierter Moleküle (Nobel Lecture)
  Angew. Chem. 1965, 77, 954–962
• Konrad Bloch*
  Die Biosynthese des Cholesterins (Nobel Lecture)
  Angew. Chem. 1965, 77, 944–954
• Feodor Lynen*
  Der Weg von der „aktivierten Essigsäure“ zu den Terpenen und Fettsäuren (Nobel Lecture)
  Angew. Chem. 1965, 77, 929–944
• Eugene P. Wigner*
  Ereignisse, Naturgesetze und Invarianzprinzipien (Nobel Lecture)
  Angew. Chem. 1964, 76, 737–742
• Maria Goeppert Mayer*
  Das Schalenmodell des Atomkerns (Nobel Lecture)
  Angew. Chem. 1964, 76, 729–737
• John Carew Eccles*
  Der Mechanismus der postsynaptischen Hemmung (Nobel Lecture)
  Angew. Chem. 1964, 76, 674–681
• Andrew Fielding Huxley*
  Die quantitative Analyse der Nervenerregung und Nervenleitung (Nobel Lecture)
  Angew. Chem. 1964, 76, 668–673
• Alan Lloyd Hodgkin*
  Ionenbewegungen als Grundlage der Nervenleitung (Nobel Lecture)
  Angew. Chem. 1964, 76, 661–668
• Giulio Natta*
  Von der stereospezifischen Polymerisation zur asymmetrischen autokatalytischen Synthese von Makromolekülen (Nobel Lecture)
  Angew. Chem. 1964, 76, 553–566
• Karl Ziegler*
  Folgen und Werdegang einer Erfindung (Nobel Lecture)
  Angew. Chem. 1964, 76, 545–553
• J. Hans D. Jensen*
  Zur Geschichte der Theorie des Atomkerns (Nobel Lecture)
  Angew. Chem. 1964, 76, 69–75
• John Cowdery Kendrew*
  Myoglobin und die Struktur der Proteine (Nobel Lecture)
  Angew. Chem. 1963, 75, 595–603
• Max Ferdinand Perutz*
  Röntgenanalyse des Hämoglobins (Nobel Lecture)
  Angew. Chem. 1963, 75, 589–595
• James Dewey Watson*
  Die Beteiligung der Ribonucleinsäure an der Proteinsynthese (Nobel Lecture)
  Angew. Chem. 1963, 75, 439–449
• Maurice Hugh Frederick Wilkins*
  Die molekulare Konfiguration der Nucleinsäure (Nobel Lecture)
  Angew. Chem. 1963, 75, 429–439
• Francis Harry Compton Crick*
  Über den genetischen Code (Nobel Lecture)
  Angew. Chem. 1963, 75, 425–429
• Melvin Calvin*
  The Path of Carbon in Photosynthesis (Nobel Lecture)
  Angew. Chem. 1962, 74, 165–186; Angew. Chem. Int. Ed. Engl. 1962, 1, 65–75
  Keywords: Nobel lecture · Photosynthesis
• Willard F. Libby
  
  Angew. Chem. 1961, 73, 225–231
• Jaroslav Heyrovský
  
  Angew. Chem. 1960, 72, 427–432
• Arthur Kornberg
  
  Angew. Chem. 1960, 72, 231–236
• Severo Ochoa
  
  Angew. Chem. 1960, 72, 225–231
• Joshua Lederberg
  
  Angew. Chem. 1959, 74, 473–480
• Alexander Todd
  
  Angew. Chem. 1958, 70, 527–531
• Nikolay N. Semenov
  
  Angew. Chem. 1957, 69, 767–777
• Cyril N. Hinshelwood
  
  Angew. Chem. 1957, 69, 445–449
• Linus Pauling
  
  Angew. Chem. 1955, 67, 241–244