Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Reviews in Angewandte Chemie, written by leading experts, summarize the important results of recent research on topical subjects in all branches of chemistry, point to unresolved problems, and discuss possible developments. Although review articles are generally written upon invitation of the editor, unsolicited manuscripts are also welcome provided they are in keeping with the character of the journal.
Prof. Dr. Ilan Marek, Dr. Ahmad Masarwa, Dr. Pierre-Olivier Delaye, Dr. Markus Leibeling
Open, sesame! The creation of new bonds has dominated the field of organic synthesis; however, selective CC cleavage (see scheme) is an important alternative for the construction of interesting molecular frameworks. This Review examines approaches to the synthesis of challenging acyclic molecular skeletons by the regio-, diastereo-, or enantioselective cleavage of carbon–carbon bonds, with a focus on the ring opening of small rings.
Prof. Dr. Yasutomo Segawa, Takehisa Maekawa, Prof. Dr. Kenichiro Itami
By no means π in the sky! The activation of aromatic CH bonds by a transition metal catalyst has received significant attention in the synthetic chemistry community. In recent years, rapid and site-selective extension of π-electron systems by C–H activation has emerged as an ideal methodology for preparing conjugated organic materials. This Review focuses on recently developments in this area directed toward new optoelectronic materials.
Dr. Nicholas H. Evans, Prof. Paul D. Beer
Since the start of this millennium, anion supramolecular chemistry has evolved substantially beyond the chemistry of anion receptors. Alongside the research that continues on the binding and sensing of anions, large strides have been made in areas which have previously been underdeveloped, such as the use of anions as templates and for membrane transportation, and importantly in chemical applications including catalysis, ion extraction, and responsive molecular systems.
Prof. Dr. Reinhard Niessner
What is soot? Soot nanoparticles produced by engines are a threat to human health. The comprehensive characterization of soot will be essential to meet future low-emission standards. This Review describes the many properties of soot nanoparticles and the possibilities to characterize them, from analysis of its morphology and biological reactivity, to its simple combustion, photoacoustic spectroscopy, and Raman scattering.
Dr. Franziska S. Hanschen, Dr. Evelyn Lamy, Prof. Dr. Monika Schreiner, Prof. Dr. Sascha Rohn
Vegetables such as broccoli contain a variety of cancer-preventing agents, among them glucosinolates. These sulfur-containing compounds are precursors to a variety of enzymatically or chemically formed breakdown products that affect the quality of food with regard to nutritional value, flavor, and beneficial health effects. This review provides an overview over the reactivity of glucosinolates and their breakdown products.
Formation of Nanoparticles and Nanostructures—An Industrial Perspective on CaCO3, Cement, and Polymers
Dr. Jens Rieger, Dr. Matthias Kellermeier, Dr. Luc Nicoleau
Intermediate nanostructures occurring during crystallization reactions play an important role in understanding and controlling the formation of particles and hybrid materials. The use of polymers allows the range of achievable properties to be broadened through their specific effects at the nanoscale—as is exemplified in this Review with calcium carbonate, zinc oxide, and cementitious systems.
Prof. James Edward Rothman
Cells contain small membrane-enclosed vesicles which transport many kinds of cargo between the compartments of the cell. The result is a choreographed program of secretory, biosynthetic and endocytic protein traffic that serves the cell’s internal physiologic needs.
The Hydrophobic Effect Revisited—Studies with Supramolecular Complexes Imply High-Energy Water as a Noncovalent Driving Force
Dr. Frank Biedermann, Prof. Dr. Werner M. Nau, Prof. Dr. Hans-Jörg Schneider
Overcoming a phobia: Hydrophobic effects are traditionally described by the association of two lipophilic molecules, which then need less water molecules for solvation than two separate solutes, thus leading to either entropy or enthalpy gain. Investigations with supramolecular complexes have shown that another mechanism based on the replacement of hydrogen-bond-deficient high-energy water molecules in cavities can play a decisive role.