Angewandte Chemie International Edition
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Cover Picture (Angew. Chem. Int. Ed. Engl. 8/1988)
The cover picture shows a schematic example of molecular self-organization. Simple double-helical complexes, so-called helicates, form spontaneously from a penta(bipyridine) ligand and Cu1 ions in solution. Whereas hydrogen bonds and stacking interactions are responsible for holding together the double helix of natural DNA, coordination interactions between Cu⊕ and bipyridine units play the key role in determining the structure of these rudimentary, double-stranded molecules. Further lengthening of the ligands should lead to self-organizing nanostructures. The field is wide open for organic, inorganic, physical, and biochemical studies: modifications of the subunit; complexation of other metal ions; investigations of binding cooperativity, of the dynamics of double helix formation and unraveling, and of the interaction with DNA; construction of self-organizing and self-amplifying devices. Further details on helicates are reported by J.-M. Lehn et al. on p. 1095 f.