Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 23

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

Cover Picture (Angew. Chem. Int. Ed. Engl. 17/1994)

33_17/1994The cover picture shows schematically a liposome with a protective polymer coating encapsulating a drug. Such sterically stabilized “Stealth liposomes” in which the polymer chains are anchored in the lipid bilayer are much more stable under biological conditions than the classical, unprotected liposomes. The extended circulation achieved is crucial for cell-specific targetting of the drug. X-ray scattering and electron microscopy have shown that the encapsulated drug is precipitated, which greatly enhances the encapsulation efficiency and stability. Danilo D. Lasic reports more about this new generation of liposomes on p. 1685ff. The picture was designed by Alenka D. Lasic.

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