Angewandte Chemie International Edition
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Cover Picture (Angew. Chem. Int. Ed. Engl. 18/1995)
The cover picture shows the palladium-catalyzed cyclization cascade of an iodotriene in the presence of CO in which “living” organopalladium species are formed as intermediates. Remarkably, this reaction succeeds with terminal alkenes that usually undergo β-dehydropalladation in the Heck reaction. E. Negishi et al. report more about this first cascade-type acylpalladation yielding polycycles with an angular mode of fusion on p. 2125 ff. In the reaction shown seven C-C bonds are formed in one step.