Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture (Angew. Chem. Int. Ed. Engl. 9/1997)
The cover picture shows a model of the binding of a protonated cyclopropane in a cation-binding site of an antibody. The larger circle gives an enlarged view of the actual binding of the organic intermediate. The aromatic and carboxylate groups are yellow, the organic intermediate silver, and the carbon atoms of the protonated cyclopropane red. The image was created with the programs Persistence of Vision and RasMol as well as proprietary software by Dr. Nicholas C. DeMello. More on the stabilization of cyclopropane intermediates is reported by J. K. Lee and K. N. Houk on pages 1003 ff.