Angewandte Chemie International Edition

Cover image for Vol. 55 Issue 27

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPlusChem, Zeitschrift für Chemie

Cover Picture (Angew. Chem. Int. Ed. 4/1999)

38_04/1999The cover picture shows a novel bone implant which is coated with highly active and selective integrin ligands. Bone-forming osteoblasts bind through αvβ3 as well as αvβ5 integrins—a class of adhesion receptors at the cell surface—to the implant coating, where they are stimulated to proliferate and form a stable interface between implant and adjoining tissue. Thus a direct contact to the tissue is established. Further details on this novel coating technique are described by Kessler et al. on pages 560–562.

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