Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Direct Catalytic Asymmetric Enolexo Aldolizations (Angew. Chem. Int. Ed. 24/2003)
A feather in the cap of the aldol reaction. The cover picture shows the amino acid (S)-proline surrounded by some new catalytic asymmetric intramolecular aldolizations, which are described by B. List et al. on page 2785 ff. Another example of the ever-increasing number of proline-catalyzed reactions are enolexo aldolizations. Despite these exciting discoveries, it is often forgotten that almost half of the 250 tonnes of proline produced each year is isolated from chicken feathers!