Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 10

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

Cover Picture: Competitive Binding Assays Made Easy with a Native Marker and Mass Spectrometric Quantification (Angew. Chem. Int. Ed. 42/2003)

42_42/2003Mass spectrometric methods are on the march in competitive binding studies. In pharmacological research these studies are widely used to characterize ligand–target interactions. However, they usually require the use of radioligands. Now, with the aid of mass spectrometry, it is possible to use native markers instead of radioligands. This method and its use in a binding study on dopamine D1-receptors are described in the Communication by G. Höfner and K. T. Wanner on page 5235 ff.

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