Angewandte Chemie International Edition

Cover image for Vol. 56 Issue 4

Editor: Peter Gölitz, Deputy Editors: Neville Compton, Haymo Ross

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

Cover Picture: Pentanuclear Platinum(ii) Macrocycles with Nucleobases (Angew. Chem. Int. Ed. 10/2004)

43_10/2004Metallocalixarenes such as the pentanuclear platinum(ii) macrocycle shown in the cover picture, are prepared from a cisplatin analogue with tertiary amine ligands and the nucleobase uracil or thymine. The platinum(ii) complex used in the synthesis of the macrocycle has a significant cytostatic activity as a result of its ability to bind to DNA. The background shows a crystal of calf thymus DNA. More details can be found in the Communication by M. J. Rauterkus and B. Krebs on page 1300 ff.

Read Full Text  | Table of Contents