Angewandte Chemie International Edition
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Chemistry and Biology of Terpene Trilactones from Ginkgo Biloba (Angew. Chem. Int. Ed. 13/2004)
Terpene trilactones from the ginkgo tree (Ginkgo biloba) are at least partly responsible for the neuromodulatory effects of G. biloba extracts. The cover picture shows a young ginkgo tree, with its characteristic fan-shaped leaves, growing out of a human brain. Superimposed are the X-ray crystal structures of bilobalide and ginkgolide B. K. Strømgaard and K. Nakanishi discuss the current status of bilobalide and ginkgolides in their Review on page 1640 ff., with a particular focus on chemical and biological studies.