Angewandte Chemie International Edition

Cover image for Vol. 57 Issue 4

Editor: Neville Compton, Deputy Editor: Frank Maass. Editor Emeritus: Peter Gölitz

Online ISSN: 1521-3773

Associated Title(s): Angewandte Chemie, Chemistry - A European Journal, Chemistry – An Asian Journal, ChemistryOpen, ChemPhotoChem, ChemPlusChem, Zeitschrift für Chemie

Cover Picture: Knotting and Threading of Molecules: Chemistry and Chirality of Molecular Knots and Their Assemblies (Angew. Chem. Int. Ed. 10/2005)

44_10/2005Fantasy structures such as the heptafoil knot interlocked with seven trefoil knots shown in the cover picture represents a distant goal for template synthesis. Established template strategies for the synthesis of molecular knots (knotanes) and higher assemblies with twisted architectures can lead to such structures. More on the synthesis, functionalization, and properties of knots can be found in the Review by F. Vögtle and O. Lukin on page 1456 ff.

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Also of Interest

Organolithium reagentsfor001

What happens in the reactions of organolithium compounds? In their Minireview on page 1448 ff., R. Gossage, J. Jastrzebski, and G. van Koten describe the formation of hetero-aggregates with remarkable structures and reactivities.

Magnetic Resonance Imagingfor002

An FeII–GdIII metallostar complex, which exhibits a remarkably high proton relaxivity and could potentially be applied in magnetic resonance imaging, is introduced by E. Tóth and co-workers in their Communication on page 1480 ff.


In their Communication on page 1504 ff., J.-L. Reymond and co-workers describe the construction of a database that contains 13.9 million organic molecules with up to 11 atoms, under constraints for chemical stability and synthetic feasibility.