Angewandte Chemie International Edition
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Pyrromethene Dialkynyl Borane Complexes for “Cascatelle” Energy Transfer and Protein Labeling (Angew. Chem. Int. Ed. 24/2005)
An energy-cascade device is created by linking ethynylpyrene fragments to boron centers. The cover picture shows such a Bodipyrene dye in which irradiation of the pyrene moiety gives a virtual Stokes shift of 10 000 cm−1. The background shows a 3D plot of a fluorescence well containing femtomolar amounts of labeled biomaterial. In their Communication on page 3694 ff., G. Ulrich, R. Ziessel, and co-workers describe how biomolecules can be labeled with these dyes, which are very promising for fluorescence imaging.
Also of Interest
Hypervalent Iodine Compounds
In his Minireview on page 3656 ff., T. Wirth describes recent advances and trends in hypervalent iodine chemistry. The stability and versatility of these compounds has opened the route to new applications in organic synthesis.
Lyases catalyze the removal of the nonacidic β protons of histidine and phenylalanine with the release of ammonia. In their Review on page 3668 ff., J. Rétey and L. Poppe summarize the latest findings that have led to revision of the long-accepted reaction mechanism.
Structural insight obtained through a combination of X-ray crystallography, NMR spectroscopy, and DFT calculations of novel oxoiron(iv) complexes with pentadentate aza ligands is discussed by L. Que, Jr., C. J. Cramer, and co-workers in their Communication on page 3690 ff.