Angewandte Chemie International Edition
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Cover Picture: Architecture and Evolution of Organic Chemistry (Angew. Chem. Int. Ed. 44/2005)
Organic synthetic reactions are treated as a connected network so that the mechanism by which organic chemistry evolved can be studied. In their Communication on page 7263 ff., B. A. Grzybowski and co-workers analyze organic syntheses reported between 1850 and 2004, thus revealing the architecture and evolution of the synthesis of molecules, and discuss the application of this technique to the chemical industry. The cover picture shows a typical “hub” in a network of organic chemistry.
Also of Interest
The increased selectivities and activities achieved in catalytic organic reactions carried out in water and by using micelle-forming amphiphilic agents is described in the Review by G. Oehme and co-workers on page 7174 ff.
Through use of the electron-localization function, N. Korber and co-workers attempt, in their Communication on page 7200 ff, to clarify the nature of the chemical bond in the P64− and As64− ions.
Stabilization of a DNA duplex containing two salicylic acid aldehyde nucleosides results from its treatment with ethylenediamine and Cu2+ or Mn2+ ions, as described by T. Carell and co-workers in their Communication on page 7204 ff.